Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Interleukin-1-beta-induced chronic inflammation promotes lung cancer metastasis

The study reveals a detailed epigenetic mechanism for how interleukin-1-beta, a common cytokine that helps fight infections during inflammation, plays a critical role in cancer metastasis.

29 Jan 2020

Researchers identify determinant protein for metastasis in alveolar rhabdomyosarcoma

Rhabdomyosarcoma is the most common childhood cancer in the soft tissues, and it is mainly originated in the muscles.

29 Jan 2020

New therapeutic strategy to fight against advanced melanoma

Scientists from the Centenary Institute have developed a new therapeutic strategy that could potentially help the fight against advanced-stage melanoma.

29 Jan 2020

Study looks into the virome of early stage, p16-positive OPSCC and neck metastasis

In this prospective study, a pan-pathogen microarray was used to determine the virome of early stage, p16-positive OPSCC and neck metastasis treated with transoral robotic surgery and neck dissection.

27 Jan 2020

Naturally produced protein suppresses breast cancer metastasis

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, predicts a better survival for breast cancer patients.

27 Jan 2020

Researchers develop new isolated limb infusion method for melanoma treatment

Worldwide, the incidence rates of skin cancer, like other types of cancer, is increasing. People in Europe and the Nordic countries are, compared to other areas of the world, at a higher risk of developing skin cancer due to their predominantly light and sun-sensitive skin type. The number of new cases of cancer in Estonia and Nordic countries has reached the same level as in sunny Australia, New Zealand and Florida. The increasing trend among Estonians to travel to southern counties is also likely to play a role in this.

27 Jan 2020

A single number aids biomedical data scientists in finding deadly cancer cells

Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could make it easier to target cancer-causing genes.

24 Jan 2020

Halting metastasis by preventing cancer cells from using fat

Healthy cells normally undergo cell division, but when a genetic mutation causes uncontrolled cell growth, they form a tumor. Cancer is one of the leading causes of death worldwide, and most deaths happen when cancer cells start to metastasize or travel from the mother tumor to other parts of the body.

23 Jan 2020

Researchers confirm safety of cancer-specific PET probe in first-in-human clinical studies

A group of researchers led by Assistant Professor WATABE Tadashi of the Graduate School of Medicine of Osaka University achieved the stable domestic production of automatic synthesis modules for positron emission tomography (PET) probe F-18 NKO-035, a LAT1-selective amino acid derivative radiolabeled with 18F, confirming its safety in first-in-human clinical studies conducted at Osaka University Hospital in November 2019.

22 Jan 2020

New melanoma test may better predict recurrence and improve patient care

Researchers at Brigham and Women's Hospital have developed a new technique that improves on the current method for assessing whether primary melanoma is likely to recur and spread, following surgical removal.

20 Jan 2020

Study shows how cancer-causing genes promote metastasis

Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing.

14 Jan 2020

NUS researchers discover new personalized tool for cancer diagnosis

A team of researchers from the National University of Singapore has discovered a new personalized tool to detect cancer, predict patient survivability and how well a cancer patient would respond to immunotherapy.

14 Jan 2020

Researchers identify new pathway as biological target for colon cancer

Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease.

13 Jan 2020

A protein found in ovarian cancer may contribute to neurodegeneration in Alzheimer's disease

Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer's disease, by combining computational methods and lab research.

13 Jan 2020

Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

To establish a molecular signature of this resistance in ovarian cancer, the authors developed preclinical tumor models of adaptive resistance to chronic anti-VEGF treatment.

8 Jan 2020

New drug compounds thwart master regulator of tumor growth, metastasis

Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes.

7 Jan 2020

Can FDA-approved flu shots be repurposed as treatments for cancer?

Changing the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and clinical studies including the most recent use of checkpoint inhibitory antibodies.

7 Jan 2020

Researchers study new immunogenic properties of already existing anti-cancer drugs

The world scientific community is waging a difficult and prolonged war on cancer. New research in the field of immunogenic cell death can extend the area of drugs application and ensure patients' protection from relapse after therapy.

3 Jan 2020

Fibroblasts involved in healing wounds play a devastating role in breast cancer development

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.

19 Dec 2019

Novel 'tooth-on-a-chip' could open door to personalized dental care

A so-called "tooth-on-a-chip" could one day enable more personalized dentistry, giving dentists the ability to identify dental filling materials that work better and last longer based on a patient's own teeth and oral microbiome.

19 Dec 2019