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Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Long DNA molecules reveal new scar types in HR-deficient cancers

DNA can be damaged by toxins, radiation, or even normal cell division, but human cells must continually fix DNA breaks to survive.

16 Aug 2023

Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

The evolutionary trends of amino acid alterations at a population scale.

16 Aug 2023

Copy number profiling provides insight as to why prostate cancer may become lethal

Researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients.

16 Aug 2023

Kidney cancer study reveals new findings about MiTF family gene mutations

A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

14 Aug 2023

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

Researchers explore the prevalence of rare genetic forms of obesity in a United Kingdom-based clinical obesity cohort.

14 Aug 2023

New gene-editing tool helps to study single-base mutations in cancer

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy.

10 Aug 2023

Experts develop clinical practice guidance for exercise assessments in people with cystic fibrosis

People living with cystic fibrosis (CF) will benefit from improved treatment as international experts produce clinical practice guidance for exercise assessments.

10 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Gene linked to Alzheimer's may also have fertility benefits

Previous research has revealed that the Apolipoprotein-ε4 (APOE-ε4) allele increases the risk for a variety of diseases in aging populations, specifically Alzheimer's and cardiovascular disease.

9 Aug 2023

Research breaks ground on new ways of treating blood disorders with gene therapy

Research from experts at Michigan Medicine, the Children's Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.

9 Aug 2023

GABA transfer between skin cells promotes melanoma initiation

The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Deep-learning technology could help scientists to develop personalized immunotherapies and vaccines

Deep-learning technology developed by a team of Johns Hopkins engineers and cancer researchers can accurately predict cancer-related protein fragments that may trigger an immune system response.

9 Aug 2023

Effect of mutations in cancer-driving genes across human cancers

Effect of mutations in cancer-driving genes across human cancers.

9 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

In a landmark moment for the Abigail Wexner Research Institute at Nationwide Children's, a 5-year-old from Bellefontaine, Ohio, received the first dose of a recently approved gene therapy for Duchenne muscular dystrophy at Nationwide Children's Hospital, where the therapy was invented and initially tested.

8 Aug 2023

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Researchers characterized the genetic architecture of IBS and investigated genetic overlap with gastrointestinal and psychiatric phenotypes.

8 Aug 2023

Unexpected link between pure mathematics and genetics discovered

An interdisciplinary team of mathematicians, engineers, physicists, and medical scientists have uncovered an unexpected link between pure mathematics and genetics, that reveals key insights into the structure of neutral mutations and the evolution of organisms.

8 Aug 2023

Mutation News and Research

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Long DNA molecules reveal new scar types in HR-deficient cancers

Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

Copy number profiling provides insight as to why prostate cancer may become lethal

Kidney cancer study reveals new findings about MiTF family gene mutations

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

New gene-editing tool helps to study single-base mutations in cancer

Experts develop clinical practice guidance for exercise assessments in people with cystic fibrosis

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

Gene linked to Alzheimer's may also have fertility benefits

Research breaks ground on new ways of treating blood disorders with gene therapy

GABA transfer between skin cells promotes melanoma initiation

Mice lacking TMCO3 gene have shortened bones

Deep-learning technology could help scientists to develop personalized immunotherapies and vaccines

Effect of mutations in cancer-driving genes across human cancers

High-level BPA exposure may affect male fertility

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Unexpected link between pure mathematics and genetics discovered

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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