Neurodegenerative Diseases News and Research

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New cloud-based data resource helps researchers to identify subtypes of ALS

A new cloud-based data resource co-developed by scientists at Cedars-Sinai provides the research community with a comprehensive set of tools to help identify new subtypes of amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

4 Feb 2022

Non-mutated ApoE protein linked to dementia

A team of researchers from the University of Kentucky's Sanders-Brown Center on Aging is working to identify new proteins that are destructive to the brain.

2 Feb 2022

Researchers develop new technique to open the blood-brain barrier in lab animals

University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

USC’s new center aims to address unmet needs in neurodegenerative diseases of the eye and brain

Could a new paradigm in digital health treat blinding disorders and possibly also be a conduit for treating other parts of the brain? A multi-disciplinary team of world-renowned researchers at USC are exploring this exciting possibility.

28 Jan 2022

Structural proteomics approaches can help in the treatment of neurodegenerative diseases

Two researchers from Skoltech and McGill University have published a review of the promising research field known as structural proteomics in the influential journal Chemical Reviews.

27 Jan 2022

Following heart-healthy lifestyle behaviors can support good brain health

The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer's disease and dementia, according to the American Heart Association's Heart Disease and Stroke Statistics - 2022 Update, published today in the Association's flagship, peer-reviewed journal Circulation.

27 Jan 2022

Nutritional components hold promise for improving the health and well-being of adults

Emerging research indicates that nutritional components that target specific mechanisms associated with age-associated cellular decline (AACD) hold promise for improving the health and well-being of adults.

25 Jan 2022

Research shows how a young healthy brain can successfully multitask while walking

New research turns the old idiom about not being able to walk and chew gum on its head. Scientists with the Del Monte Institute for Neuroscience at the University of Rochester have shown that the healthy brain is able to multitask while walking without sacrificing how either activity is accomplished.

25 Jan 2022

The long-term neurologic consequences of COVID-19

A team of researchers recently provided insights into central nervous system consequences of the coronavirus disease 2019 (COVID-19) in a perspective paper published in the Science journal.

24 Jan 2022

Scientists identify a new switch for controlling motor proteins

Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks.

21 Jan 2022

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

By mapping all the protein interactions of a dementia-linked protein in the brain called Tau, a team of Weill Cornell Medicine investigators has created a road map for identifying potential new treatment targets for Alzheimer's disease and related dementia.

21 Jan 2022

Researchers uncover new findings about the role of tau in neurodegenerative disease

Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists found that mutant tau impacts the function of mitochondria in human neurons.

20 Jan 2022

Mice study identifies ventral spinocerebellar tract neurons that control locomotion

For more than a century, scientists have known that while the commands that initiate movement come from the brain, the neurons that control locomotion once movement is underway reside within the spinal cord.

20 Jan 2022

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Eikonoklastes Therapeutics, a preclinical stage biopharmaceutical company, today announced it has completed a license with the University of California San Diego to add a novel gene therapy for the treatment of neurodegenerative diseases.

20 Jan 2022

Scientists reveal toxic astrocyte changes in ALS

Scientists at the Francis Crick Institute have revealed harmful changes in supporting cells, called astrocytes, in Amyotrophic Lateral Sclerosis (ALS) in two publications in Brain and Genome Research.

19 Jan 2022

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

New research assesses the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation in response to SARS-CoV-2 and its spike protein, and the effects of this exposure in the presence of a-synuclein protein aggregate fibrils.

17 Jan 2022

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Jianhan Chen, a University of Massachusetts Amherst chemistry and biochemistry and molecular biology professor, has received a five-year, $2 million National Institutes of Health (NIH) grant to support research in his computational biophysics lab aimed at better understanding the role of intrinsically disordered proteins (IDPs) in biology and human disease.

16 Jan 2022

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Long before the onset of dementia, there is evidence for increased activity of the brain's immune system. Researchers from DZNE and the University Hospital Bonn come to this conclusion based on a study of more than 1,000 older adults.

12 Jan 2022

Novel insights about dopamine can help find better drugs for Parkinson's patients

New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's.

12 Jan 2022

Neurodegenerative Diseases News and Research

New cloud-based data resource helps researchers to identify subtypes of ALS

Non-mutated ApoE protein linked to dementia

Researchers develop new technique to open the blood-brain barrier in lab animals

Study reveals potential mechanism for iron accumulation in the aging brain

USC’s new center aims to address unmet needs in neurodegenerative diseases of the eye and brain

Structural proteomics approaches can help in the treatment of neurodegenerative diseases

Following heart-healthy lifestyle behaviors can support good brain health

Nutritional components hold promise for improving the health and well-being of adults

Research shows how a young healthy brain can successfully multitask while walking

The long-term neurologic consequences of COVID-19

Scientists identify a new switch for controlling motor proteins

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

Researchers uncover new findings about the role of tau in neurodegenerative disease

Mice study identifies ventral spinocerebellar tract neurons that control locomotion

Eikonoklastes completes a license to add novel gene therapy for treating neurodegenerative diseases

Scientists reveal toxic astrocyte changes in ALS

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Novel insights about dopamine can help find better drugs for Parkinson's patients

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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