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New compound could alleviate neurological symptoms of CHARGE syndrome

CHARGE syndrome is a rare genetic disorder affecting about 1 in 10,000 newborns. It can lead to neurological and behavioural disorders for which no treatment is currently available.

28 Apr 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

Traumatic brain injury and Alzheimer's disease share common trajectories

Brain changes in people with Alzheimer's disease and in those with mild traumatic brain injuries (TBIs) have significant similarities, a new USC study shows, suggesting new ways to identify patients at high risk for Alzheimer's.

26 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

New miniaturized model of neuromuscular junction formation provides insight into ALS

Skeletal muscles enable voluntary movements and are controlled by a special type of neurons called motor neurons, which make direct contact with skeletal muscles through so-called neuromuscular junctions (NMJs).

22 Apr 2021

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

20 Apr 2021

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Alzheimer's disease (AD) is a form of progressive dementia interfering with daily living. It is caused by the decline in the number of brain cells resulting in the deterioration of our mental abilities.

20 Apr 2021

New implantable tool images brain activity in 3D

Tools that allow neuroscientists to record and quantify functional activity within the living brain are in great demand. Traditionally, researchers have used techniques such as functional magnetic resonance imaging, but this method cannot record neural activity with high spatial resolution or in moving subjects.

20 Apr 2021

Simple dietary supplement ameliorates schizophrenic traits in mice

A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia.

19 Apr 2021

New study sheds light on complex brain process that helps learn and form new memories

Making memories involves more than seeing friends or taking photos. The brain constantly adapts to new information and stores memories by building connections among neurons, called synapses. How neurons do this--reaching out arm-like dendrites to communicate with other neurons--requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery.

19 Apr 2021

Study sheds light on how tau aggregates promote Alzheimer’s disease

Look deep inside the brain of someone with Alzheimer's disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you'll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau.

17 Apr 2021

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Neurological disorders are the number one cause of disability in the world, leading to seven million deaths each year. Yet few treatments exist for these diseases, which progressively diminish a person's ability to move and think.

16 Apr 2021

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS).

15 Apr 2021

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

A Keele researcher will embark on a two-year study to identify affordable treatments to help children living with spinal muscular atrophy.

15 Apr 2021

Study reveals how neural systems process and store information

Research breakthrough in understanding how neural systems process and store information. A team of scientists from the University of Exeter and the University of Auckland have made a breakthrough in the quest to better understand how neural systems are able to process and store information.

15 Apr 2021

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

From optogenetics to sonogenetics to magnetognetics, scientists around the world are investigating new techniques to treat Parkinson's disease without the need for invasive surgery.

13 Apr 2021

Researchers identify new potential mechanism for age-related macular degeneration

Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration - the leading cause of blindness among older adults.

13 Apr 2021

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

This study builds upon two earlier published studies (Mold et al., 2020, Journal of Alzheimer's Disease Reports) from the same group. The new data, also published in the Journal of Alzheimer's Disease Reports, demonstrate that aluminum is co-located with phosphorylated tau protein, present as tangles within neurons in the brains of early-onset or familial Alzheimer's disease (AD).

9 Apr 2021

New cell counting method offers a robust protocol for studying animal brains

Using a surprisingly simple technique, researchers in the University of Arizona Department of Neuroscience have succeeded in approximating how many brain cells make up the brains of several species of bees, ants and wasps.

9 Apr 2021

Neuron News and Research

New compound could alleviate neurological symptoms of CHARGE syndrome

Scientists identify many genes that are important in fruit flies' neuron development

Traumatic brain injury and Alzheimer's disease share common trajectories

Experimental drug reverses key symptoms of Alzheimer's disease in mice

New miniaturized model of neuromuscular junction formation provides insight into ALS

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

New implantable tool images brain activity in 3D

Simple dietary supplement ameliorates schizophrenic traits in mice

New study sheds light on complex brain process that helps learn and form new memories

Study sheds light on how tau aggregates promote Alzheimer’s disease

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Japanese–European scientists detect novel genetic mitochondrial disorder

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

Study reveals how neural systems process and store information

Non-invasive neuromodulation approaches can prevent invasive surgery in Parkinson's patients

Researchers identify new potential mechanism for age-related macular degeneration

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

New cell counting method offers a robust protocol for studying animal brains

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