Omicron News and Research

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Natural and hybrid immunity dynamics in South African mothers

Researchers evaluated natural and hybrid immunity after four COVID-19 waves in South Africa.

24 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Researchers characterized the persistence and infectivity of SARS-CoV-2 Omicron among children.

24 Jun 2022

Mapping the trajectory of SARS-CoV-2 evolution inside the host

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States mapped the trajectory of within-host evolution of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

24 Jun 2022

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

The original SARS-CoV-2 viral strain that emerged in early 2020 was able to latch on to sugars known as sialic acids, found on the surface of human cells, an ability that later strains did not retain.

24 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

Scientists have focused on studying the mutational frequency of SARS-CoV-2 proteome based on structural characteristics.

23 Jun 2022

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

In a recent study published in the Cochrane Library, researchers searched multiple databases to identify randomized controlled trials (RCTs) that evaluated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐neutralizing monoclonal antibodies (mAbs).

23 Jun 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

First open-source program can improve detection and tracking of pathogenic DNA sequences

It's a given that certain bacteria and viruses can cause illness and disease, but the real culprits are the sequences of concern that lie within the genomes of these microbes.

21 Jun 2022

Epidemiological characteristics and transmission dynamics of the Omicron outbreak under lockdown policies in Shanghai

Researchers assessed the epidemiological characteristics of the SARS-CoV-2 Omicron variant outbreak in Shanghai, China.

21 Jun 2022

The impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant

Researchers assessed the impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant.

21 Jun 2022

Only 20% of Americans have effective protection against Omicron infection

In a recent research paper published in the Clinical Infectious Diseases journal, scientists analyzed the population immunity against pre-Omicron and Omicron severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) variants in U.S. counties and states up until December 1, 2021. Background

21 Jun 2022

An estimate of Omicron's fitness advantage

Researchers quantify the transmission advantage of the SARS-CoV-2 Omicron variant across forty countries.

21 Jun 2022

Each SARS-CoV-2 reinfection causes more severe disease

In a recent study under review at the Nature Portfolio journal and currently posted to the Research Square* preprint server, researchers at Washington University School of Medicine and VA Saint Louis Health Care System showed that acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection adds to the risks of all-cause mortality and hospitalization accrued during the first SARS-CoV-2 infection.

20 Jun 2022

Real-world study shows Paxlovid associated with lower hospitalization rates

In a recent study posted to the medRxiv* pre-print server, researchers investigated the effectiveness of nirmatrelvir plus ritonavir in preventing hospitalizations among individuals aged 50 or older and vaccinated for coronavirus disease 2019 (COVID-19).

20 Jun 2022

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

In a recent study published in the journal Nature Medicine, researchers assessed the coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE) against symptomatic infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs) by genetic mismatch/distance (GD) analysis.

20 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

Omicron News and Research

Natural and hybrid immunity dynamics in South African mothers

Associations between maternal COVID-19 vaccination and hospitalization among infants

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Mapping the trajectory of SARS-CoV-2 evolution inside the host

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

COVID-19 outcomes improved for SARDs patients through Omicron wave

First open-source program can improve detection and tracking of pathogenic DNA sequences

Epidemiological characteristics and transmission dynamics of the Omicron outbreak under lockdown policies in Shanghai

The impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant

Only 20% of Americans have effective protection against Omicron infection

An estimate of Omicron's fitness advantage

Each SARS-CoV-2 reinfection causes more severe disease

Real-world study shows Paxlovid associated with lower hospitalization rates

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

How effective are mRNA COVID-19 vaccine boosters against Omicron?

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