immunity News and Research

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Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

An article published in the journal Cell describes a study that enabled a group of researchers to discover how SARS-CoV-2 evades the cytotoxic immune response by identifying a protein called ORF6 that is a key factor in this mechanism.

16 Jul 2024

Navigating adjuvant therapy options in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies globally and is the third leading cause of cancer-related deaths.

16 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

Early antibiotic exposure can trigger long term susceptibility to asthma

Early exposure to antibiotics can trigger long term susceptibility to asthma, according to new research from Monash University.

15 Jul 2024

Study offers insights on prevalence and risk factors of persistent post-COVID-19 symptoms

Early on during the coronavirus pandemic, there were reports of cases of persistent post-infection symptoms.

14 Jul 2024

UQ study offers insights into how Haemophilus influenzae manipulates the immune system

Researchers from The University of Queensland have identified how a common bacterium is able to manipulate the human immune system during respiratory infections and cause persistent illness.

12 Jul 2024

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Chromosome 18q deletion (18q del) syndromeis a rare genetic condition disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18.

11 Jul 2024

Optimizing influenza vaccine strategies with nanoparticle immunization

To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a study by researchers in the Institute for Biomedical Sciences at Georgia State University.

11 Jul 2024

Finland is offering farmworkers bird flu shots. Some experts say the US should, too.

As bird flu spreads among dairy cattle in the U.S., veterinarians and researchers have taken note of Finland's move to vaccinate farmworkers at risk of infection. They wonder why their government doesn't do the same.

11 Jul 2024

Liver's defense mechanism hinders immunity in chronic hepatitis B, study reveals

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells blood vessels in the liver start a "sleep timer" that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies.

11 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Non-invasive saliva test could identify children missing tetanus immunity

University of Birmingham experts are developing a non-invasive saliva test that - within 15 minutes - might identify children across the Global South missing immunity to tetanus who may also have missed out on essential vaccines.

8 Jul 2024

Understanding the platelet-monocyte interaction to improve treatment of immune disorders

Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response.

8 Jul 2024

Cutting-edge tools and practices revolutionize gut microbiome research

Research explores cutting-edge tools and best practices for studying gut microbial community metabolism, aiming to enhance our understanding and manipulation of the human gut microbiome for better health outcomes.

7 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

New deadly strain of mpox found in DRC could spread exponentially among humans

Concerns are growing about an outbreak of deadly mpox caused by a novel, sexually transmitted strain of the virus in the southeast of the Democratic Republic of Congo (DRC).

5 Jul 2024

immunity News and Research

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

Navigating adjuvant therapy options in hepatocellular carcinoma

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Researchers discover key functions of IRF1 in cancer progression and treatment response

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Early antibiotic exposure can trigger long term susceptibility to asthma

Study offers insights on prevalence and risk factors of persistent post-COVID-19 symptoms

UQ study offers insights into how Haemophilus influenzae manipulates the immune system

Unveiling late-onset combined immunodeficiency in patients with 18q del syndrome

Optimizing influenza vaccine strategies with nanoparticle immunization

Finland is offering farmworkers bird flu shots. Some experts say the US should, too.

Liver's defense mechanism hinders immunity in chronic hepatitis B, study reveals

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Non-invasive saliva test could identify children missing tetanus immunity

Understanding the platelet-monocyte interaction to improve treatment of immune disorders

Cutting-edge tools and practices revolutionize gut microbiome research

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

New deadly strain of mpox found in DRC could spread exponentially among humans

Industry Focus eBook - Cell biology (5th edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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