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Breastmilk sugars may help prevent prenatal infections

Breastfeeding has long been used as a method to help keep newborns healthy and protected against a variety of diseases. But certain sugars naturally found in breastmilk could also help prevent infections before a baby arrives.

9 Aug 2023

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

In a study published in the journal Foods, researchers reviewed available literature on the potential anti-Alzheimer's disease properties of mushrooms.

9 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Spatially-resolved macrophage phenotyping in liver disease-related research

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.

8 Aug 2023

RAGE plays key role in cellular mechanisms of plasticity in aggressive triple-negative breast cancer

Published online ahead of print in the journal Oncogene , a study led by Josep Villanueva, an Investigator at the Vall d'Hebron Institute of Oncology (VHIO), shows that the receptor for advanced glycation end-product (RAGE) plays a key role in cellular mechanisms of plasticity in mesenchymal triple-negative breast cancer (TNBC) that transform epithelial cells into mesenchymal cells as potent drivers of cancer cell proliferation and tumor invasion.

8 Aug 2023

UTHSC professor receives $2.56 million to continue glioblastoma research

Lawrence Pfeffer, PhD, Professor in the Department of Pathology at the University of Tennessee Health Science Center, recently was awarded $2.56 million from the National Cancer Institute over the next five years to identify and target molecular pathways that will enhance glioblastoma's sensitivity to currently approved drug therapies.

7 Aug 2023

Bone mineralization found to dampen metastatic progression of breast cancer

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis.

7 Aug 2023

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys.

3 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

New drug targets EMT in cancer, reducing metastasis and resistance to chemotherapy

Metastases and resistance to chemotherapy are the main causes of treatment failure and mortality in cancer patients.

2 Aug 2023

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

With a survival rate in the single digits, pancreatic ductal adenocarcinoma (PDAC) is highly lethal. In fact, by the time PDAC is clinically diagnosed, it is already considered incurable via surgery or other means in up to 90% of patients.

2 Aug 2023

The influence of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal, and renal functions in mice

The toxic effects of aerosol exposure from electronic cigarettes (ECs) and cigarette smoke (CS) on mice.

2 Aug 2023

Study provides new insights into the intricate cellular processes driving heterotopic ossification

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation.

1 Aug 2023

Penn Medicine and CHOP receive $26 million NIH grant to develop treatments for three rare genetic diseases

A Penn Medicine and Children's Hospital of Philadelphia (CHOP) team will seek to develop treatments for three rare, incurable genetic diseases with the help of a $26 million grant from the National Institutes of Health (NIH).

1 Aug 2023

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

A group of researchers investigated the neurotropic potential of SARS-CoV-2 and its variants by studying their ability to invade the brain through the olfactory pathway in hamsters.

1 Aug 2023

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

1 Aug 2023

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Researchers compared the shared genetic risk and biological foundations of neurological and mental illnesses.

1 Aug 2023

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Human senescent fibroblasts trigger progressive lung fibrosis in mice."

31 Jul 2023

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Researchers investigated the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma.

31 Jul 2023

The essential role of the MPL36 protein in leptospirosis

The Leptospira membrane protein L36 (MPL36) is essential for its pathogenesis.

31 Jul 2023

in vivo News and Research

Breastmilk sugars may help prevent prenatal infections

Are mushrooms an effective early dietary intervention for Alzheimer’s Disease?

The impact of epigenetic features on breast cancer treatment and outcomes

Spatially-resolved macrophage phenotyping in liver disease-related research

RAGE plays key role in cellular mechanisms of plasticity in aggressive triple-negative breast cancer

UTHSC professor receives $2.56 million to continue glioblastoma research

Bone mineralization found to dampen metastatic progression of breast cancer

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

UCLA study finds new way to protect livers during transplantation

New drug targets EMT in cancer, reducing metastasis and resistance to chemotherapy

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

The influence of electronic cigarette aerosol and cigarette smoke on cardiovascular, gastrointestinal, and renal functions in mice

Study provides new insights into the intricate cellular processes driving heterotopic ossification

Penn Medicine and CHOP receive $26 million NIH grant to develop treatments for three rare genetic diseases

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

The essential role of the MPL36 protein in leptospirosis

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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