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SENRI Trial: NK1 antagonists may prevent emesis in patients treated with oxaliplatin-based chemotherapy

The SENRI trial has opened the window to evaluate NK1 antagonists for emesis prevention in patients taking oxaliplatin chemotherapy, antiemetics expert and ESMO spokesperson Fausto Roila said, putting into perspective the results of a Japanese study presented today at the ESMO 17th World Congress on Gastrointestinal Cancer 2015 in Barcelona.

2 Jul 2015

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

Substituting deuterium for certain hydrogen atoms in molecules has been shown to enhance the metabolic properties of a number of drugs and provides a promising approach to the discovery and development of innovative drug products.

2 Jul 2015

IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

Scientists from the Instituto de Investigación Biomédica [Institute of Biomedical Research], in Galicia (Spain), have made progress in the identification of new biomarkers for improving prevention of colorectal cancer.

1 Jul 2015

Damon Runyon creates new award to increase number of physician-scientists

Physician-scientists are crucial to moving scientific discoveries from the lab to patients, but their numbers have been dwindling just when they are needed most, particularly in cancer research, as the number of cancer cases is projected to increase by 45 percent in the next fifteen years and elevate cancer to the leading cause of death in America.

1 Jul 2015

Two migraine surgery techniques equally effective in reducing severity of migraine headaches

Two migraine surgery techniques targeting a specific "trigger site" are both highly effective in reducing the frequency and severity of migraine headaches, according to a randomized trial in the July issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

1 Jul 2015

New review may help women with stress urinary incontinence make more informed choices about treatment

A new Cochrane systematic review published today of surgery for stress urinary incontinence makes an important contribution to an ongoing debate and will help women to make more informed choices about treatment.

1 Jul 2015

Kessler Foundation receives $3 million to improve cognition and mobility of people with TBI

The New Jersey Commission on Brain Injury Research awarded $3 million in grants to Kessler Foundation, half of its total grant distribution in 2015, to improve cognition and mobility of individuals with traumatic brain injury (TBI).

1 Jul 2015

Pinaverium offers quick relief from IBS symptoms

Pinaverium offers quick and effective relief of irritable bowel syndrome (IBS) symptoms, according to clinical trial results published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

30 Jun 2015

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

Pharma Two B Ltd., a privately held company developing innovative therapeutics based on previously approved drugs, announced today the successful results of the company's Phase IIb pivotal study of P2B001 for the treatment of early stage Parkinson's Disease (PD).

30 Jun 2015

Oramed Pharmaceuticals submits study protocol to FDA for Phase IIb trial of ORMD-0801

Oramed Pharmaceuticals Inc., a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, announced today that it has submitted the study protocol for the company's Phase IIb trial of ORMD-0801, its oral insulin capsule, to the U.S. Food and Drug Administration.

30 Jun 2015

Aeterna Zentaris recruits patients for ZoptEC Phase 3 study in women with advanced endometrial cancer

Aeterna Zentaris Inc. today announced it has reached its goal of recruiting 500 patients for its pivotal Phase 3 ZoptEC (Zoptarelin Doxorubicin in Endometrial Cancer) clinical study with zoptarelin doxorubicin in women with advanced, recurrent or metastatic endometrial cancer.

30 Jun 2015

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

In a first for HIV prevention, an international team of researchers have completed follow-up of participants enrolled in a pivotal Phase III trial that tested the safety and effectiveness of a vaginal ring for preventing HIV in women.

30 Jun 2015

Axovant Sciences accepts two presentations at Alzheimer's Association International Conference 2015

Axovant Sciences Ltd., a leading clinical-stage biopharmaceutical company focused on the treatment of dementia, today announced the acceptance of two presentations at the Alzheimer's Association International Conference 2015 (AAIC) being held in Washington, D.C. from July 18-23, 2015.

30 Jun 2015

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

The amphetamine-based drug Evekeo, given once or twice daily to children 6-12 years of age, is effective in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and improving performance in a laboratory classroom setting, according to the results of a new study published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Jun 2015

Can-Fite reports further progress in continuing preclinical program of CF602 sexual dysfunction drug

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, today reported further progress in its continuing preclinical program of its CF602 drug candidate as the Company prepares to file an investigational new drug (IND) application with the U.S. Food and Drug Administration to allow the initiation of a Phase I clinical study.

29 Jun 2015

Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Since 2014, more than 16 million anti-malarial treatments derived from the Sanofi patented process for semi-synthetic artemisinin have been supplied to endemic countries in Africa.

From Sanofi 28 Jun 2015

Helen DeVos Children's Hospital uses two imaging techniques to produce hybrid 3D model of a patient's heart

Congenital heart experts from Spectrum Health Helen DeVos Children's Hospital have successfully integrated two common imaging techniques to produce a three-dimensional anatomic model of a patient's heart.

27 Jun 2015

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

The first test in a mammalian model of a potential new class of drugs to treat Parkinson's disease shows abatement of neurodegeneration in the brains of test rats and no significant toxicities, University of Alabama at Birmingham and Pfizer Inc. researchers report online in The Journal of Biological Chemistry.

26 Jun 2015

UC Santa Barbara professor develops novel therapeutic strategy for PKD

For the 12 million people worldwide who suffer from polycystic kidney disease (PKD), an inherited disorder with no known cure, a new treatment option may be on the horizon.

26 Jun 2015

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Investigators from Dartmouth's Norris Cotton Cancer Center harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer.

25 Jun 2015

Efficacy News and Research

SENRI Trial: NK1 antagonists may prevent emesis in patients treated with oxaliplatin-based chemotherapy

Concert Pharmaceuticals’ precision deuteration platform can enhance metabolic properties of drugs

IBI scientists make progress in identifying new biomarkers for preventing colorectal cancer

Damon Runyon creates new award to increase number of physician-scientists

Two migraine surgery techniques equally effective in reducing severity of migraine headaches

New review may help women with stress urinary incontinence make more informed choices about treatment

Kessler Foundation receives $3 million to improve cognition and mobility of people with TBI

Pinaverium offers quick relief from IBS symptoms

Pharma Two B reports positive results from P2B001 Phase IIb study for treatment of early stage PD

Oramed Pharmaceuticals submits study protocol to FDA for Phase IIb trial of ORMD-0801

Aeterna Zentaris recruits patients for ZoptEC Phase 3 study in women with advanced endometrial cancer

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

Axovant Sciences accepts two presentations at Alzheimer's Association International Conference 2015

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

Can-Fite reports further progress in continuing preclinical program of CF602 sexual dysfunction drug

Artemisinin and the fight against malaria: an interview with Dr. Robert Sebbag, Sanofi

Helen DeVos Children's Hospital uses two imaging techniques to produce hybrid 3D model of a patient's heart

Potential new class of drugs lessen neurodegeneration in rat model of Parkinson's disease

UC Santa Barbara professor develops novel therapeutic strategy for PKD

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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