Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Combination of PD-991 and letrozole improves survival in patients with HER2- breast cancer

Pfizer Inc. today announced randomized Phase 2 data that showed PD-0332991 (PD-991) in combination with letrozole significantly extended progression free survival (PFS) compared with letrozole alone in post-menopausal patients with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or metastatic breast cancer.

6 Dec 2012

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

Marking a major milestone in what has become a fast-growing standard of care in prostate cancer surgery, the chief of urologic oncology at The Cancer Institute of New Jersey has completed his 1,000th robotic prostatectomy at Robert Wood Johnson University Hospital (RWJUH), the Flagship Hospital of The Cancer Institute of New Jersey, which is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.

6 Dec 2012

African American women less likely to receive axillary SLN biopsy for breast cancer

African American women with early stage, invasive breast cancer were 12 percent less likely than Caucasian women with the same diagnosis to receive a minimally invasive technique, axillary sentinel lymph node (SLN) biopsy, years after the procedure had become the standard of surgical practice, according to research from The University of Texas MD Anderson Cancer Center.

6 Dec 2012

Moderna Therapeutics closes $40M in financing

Moderna Therapeutics announced today that it has closed more than $40 million in financing to date, led by Flagship Ventures and private investors, which will be used to advance multiple programs toward clinical stage development.

6 Dec 2012

Tyk2 enzyme helps regulate obesity through differentiation of brown adipose tissue

Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic illnesses. But an international team of scientists led by Virginia Commonwealth University Massey Cancer Center researcher Andrew Larner, M.D., Ph.D., has successfully reversed obesity in mice by manipulating the production of an enzyme known as tyrosine-protein kinase-2 (Tyk2).

6 Dec 2012

Old age no barrier to rectal resection

Advanced age alone should not rule out curative resection for rectal cancer, say the authors of a systematic review.

5 Dec 2012

Inserm prizes for medical research to be awarded on Dec. 3

The 2012 Inserm prizes for medical research will be awarded at a ceremony at the Coll-ge de France on Monday 3 December 2012. This year, the grand prize will be awarded to Philippe Sansonetti in the presence of Marisol Touraine, France's Minister of Social Affairs and Health, Genevi-ve Fioraso, France's Minister of Higher Education and Research, and Professor Andr- Syrota, Chairman and CEO of Inserm.

5 Dec 2012

National Radiation Oncology Registry program for quality assessment and improvement

The National Radiation Oncology Registry (NROR) pilot program will serve as the basis for the creation of a nationwide electronic registry to capture reliable, population-based information on radiation treatment delivery and health outcomes and will be supported by an innovative information technology (IT) infrastructure that will maximize efficiency through the automated collection and electronic transfer of data, according to research presented at the American Society for Clinical Oncology (ASCO) Quality Care Symposium.

5 Dec 2012

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

AstraZeneca today announced the presentation of important new data from studies of FASLODEX (fulvestrant) Injection at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium taking place from 4-8 December at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

5 Dec 2012

METACARDIS project to develop and implement personalized treatments for patients with CMDs

Thanks to the support of the European Commission, fourteen partners in six European countries will work together over a five-year period to translate the results obtained with novel CMD diagnosis and treatment methods and pave the way for personalised medicine in CMDs. Researchers and clinicians from the Institute of Cardiometabolism and Nutrition (ICAN) will also be involved in the METACARDIS project.

5 Dec 2012

Researchers investigate GPER receptor as possible new drug target for breast cancer

Five-year breast cancer survival rates have improved dramatically over the past 50 years, but tumors can recur up to ten or more years after they are detected. When tumors recur, they are even more difficult to treat.

5 Dec 2012

Natural killer cell response detrimental to glioblastoma virotherapy

For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor.

5 Dec 2012

Combination of ketogenic diet and radiation therapy effectively treats malignant gliomas

A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy.

5 Dec 2012

Cabozantinib effectively treats prostate cancer spread to bones

A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.

5 Dec 2012

The Leapfrog Group honors Northwestern Memorial and Lake Forest with 'A' Hospital Safety Score

Memorial Hospital and Northwestern Lake Forest Hospital have been selected as 2012 Top Hospitals by The Leapfrog Group, an organization that provides the only national, public comparison of hospitals across safety, quality and efficiency dimensions. Northwestern Memorial and Northwestern Lake Forest are honored among an elite group of only 92 hospitals selected out of nearly 1,200 surveyed.

4 Dec 2012

Studies explore F-18-FLT PET utility in providing prognostic information for patients with gliomas

In the management of gliomas-or tumors that originate in the brain-precise assessment of tumor grade and the proliferative activity of cells plays a major role in determining the most appropriate treatment and predicting overall survival.

4 Dec 2012

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

The addition of selumetinib to docetaxel therapy may boost the survival of patients with KRAS-mutant non-small-cell lung cancer, suggest study findings published in The Lancet Oncology.

3 Dec 2012

Single-dose radiotherapy best for painful spine metastases

Research supports the use of single-fraction radiotherapy for the treatment of painful vertebral bone metastases.

3 Dec 2012

Elderly depression at discharge related to future outcomes

The number of depressive symptoms present in elderly patients at hospital discharge is associated with their future functional and mortality outcomes, indicate study results.

3 Dec 2012

Metformin improves survival in diabetic patients with ovarian cancer

Diabetic patients with ovarian cancer who took the drug metformin for their diabetes had a better survival rate than patients who did not take it, a study headed by Mayo Clinic shows. The findings, published early online in the journal Cancer, may play an important role for researchers as they study the use of existing medications to treat different or new diseases.

3 Dec 2012

Oncology News and Research

Further Reading

Combination of PD-991 and letrozole improves survival in patients with HER2- breast cancer

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

African American women less likely to receive axillary SLN biopsy for breast cancer

Moderna Therapeutics closes $40M in financing

Tyk2 enzyme helps regulate obesity through differentiation of brown adipose tissue

Old age no barrier to rectal resection

Inserm prizes for medical research to be awarded on Dec. 3

National Radiation Oncology Registry program for quality assessment and improvement

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

METACARDIS project to develop and implement personalized treatments for patients with CMDs

Researchers investigate GPER receptor as possible new drug target for breast cancer

Natural killer cell response detrimental to glioblastoma virotherapy

Combination of ketogenic diet and radiation therapy effectively treats malignant gliomas

Cabozantinib effectively treats prostate cancer spread to bones

The Leapfrog Group honors Northwestern Memorial and Lake Forest with 'A' Hospital Safety Score

Studies explore F-18-FLT PET utility in providing prognostic information for patients with gliomas

Selumetinib plus docetaxel shows KRAS-mutant NSCLC potential

Single-dose radiotherapy best for painful spine metastases

Elderly depression at discharge related to future outcomes

Metformin improves survival in diabetic patients with ovarian cancer

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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