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Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).

2 May 2022

New insights on the mechanisms of transmission of bacterial pathogen that causes listeriosis

Listeriosis is a zoonotic disease of food origin that can cause, both in the human species and in animals, symptoms of gastroenteritis, meningitis, bacteremia and miscarriages.

2 May 2022

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

Researchers at the Case Western Reserve University School Medicine have found that combining two cancer drugs can be effective in treating a specific type of colorectal cancer, according to a new study published in Nature Communications.

2 May 2022

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Researchers evaluated the importance of the P681 residue within the furin cleavage site of SARS-CoV-2 spike protein in determining the fusogenicity and syncytia formation ability of SARS-CoV-2 strains.

2 May 2022

Longitudinal and proteome-wide analysis of antibodies in COVID-19 patients using a SARS-CoV-2 proteome microarray

The first longitudinal proteome-wide analysis of antibodies in COVID-19 patients has been performed by researchers from the Beijing Institute of Microbiology and Epidemiology and published in the Journal of Advanced Research.

2 May 2022

The generation of SARS-CoV-2 virus-like particles in insect cells

Researchers have reported the development of a promising COVID-19 vaccine candidate which is based on SARS-CoV-2 VLPs, derived from the co-expression of the spike, membrane, and envelope structural proteins in the baculovirus expression system.

2 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

SARS-CoV-2-specific T cells are broader after vaccination than after infection

In a recent study published in the Nature Microbiology journal, researchers investigated the characteristics of coronavirus disease 2019 (COVID-19) infection in convalescent and vaccinated individuals.

1 May 2022

How diet and nutrition impacts lifespan

In a recent study published in the journal Cell, researchers analyzed the association between human longevity to growth and metabolic pathways.

1 May 2022

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

In a recent study published in the Nature Microbiology journal, researchers assessed the longitudinal viral dynamics in asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

1 May 2022

$Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?$

Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?

A recent research paper posted to the Research Square* preprint server assessed the dose fractionation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

1 May 2022

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

A recent research paper posted to the bioRxiv* preprint server demonstrated that a cocktail of two synergetic antibodies extensively neutralized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including Omicron BA.1 and BA.2.

1 May 2022

Roswell Park's nursing teams share research at 47th Annual Congress of the Oncology Nursing Society

Several nursing teams from Roswell Park Comprehensive Cancer Center were invited to share their research at the 47th Annual Congress of the Oncology Nursing Society, which is underway in Anaheim, California, and continues through May 1, 2022.

29 Apr 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Study reveals new approach for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds.

29 Apr 2022

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

A recent article published in the Med journal reported that the SARS-CoV-2 booster vaccinations enhance the SARS-CoV-2 Omicron sublineage neutralizations.

29 Apr 2022

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Researchers discussed the validity of the equation derived by Khoury et al. and reported by Muena et al. regarding the immunological correlate of protection to predict the efficacy of new coronavirus vaccines in a real-world setting.

29 Apr 2022

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

B Cell News and Research

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

New insights on the mechanisms of transmission of bacterial pathogen that causes listeriosis

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Longitudinal and proteome-wide analysis of antibodies in COVID-19 patients using a SARS-CoV-2 proteome microarray

The generation of SARS-CoV-2 virus-like particles in insect cells

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

SARS-CoV-2-specific T cells are broader after vaccination than after infection

How diet and nutrition impacts lifespan

SARS-CoV-2 viral shedding varies widely in asymptomatic and mildly ill patients

Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

Roswell Park's nursing teams share research at 47th Annual Congress of the Oncology Nursing Society

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Probenecid shows activity against respiratory syncytial virus

Study reveals new approach for engineering stable articular cartilage

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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