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New DNA technology to study cystic fibrosis 'superbug' during infection

The bacterium, called Pseudomonas aeruginosa, is the most common cause of persistent and fatal lung infections in cystic fibrosis patients. Scientists at Liverpool identified a particularly virulent strain of the bacteria that is transmissible between patients. The Liverpool Epidemic Strain (LES), referred to as a cystic fibrosis 'superbug', can cause aggressive infection and results in progressive lung decline.

23 Feb 2011

Mechanism of cancer treatment related to infertility in women

Chemotherapeutic agents, used in cancer treatment, destroy not only cancer cells but also healthy cells, thus affecting germ cells as well. Consequently, after surviving cancer many female patients are confronted with the diagnosis: infertility. For a long time a relationship between infertility and chemotherapeutic agents has been assumed, but until now, the exact mechanism was not known.

23 Feb 2011

Researchers to explore genomes of childhood cancers

In a project supported by Genome BC, a Vancouver pediatric pathologist at the BC Cancer Agency/University of British Columbia is leading the team that will explore the genomes of four of the most challenging childhood cancers known.

23 Feb 2011

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

A group of researchers led by scientists from the Virginia Bioinformatics Institute at Virginia Tech have developed a new technology that detects distinct genetic changes differentiating cancer patients from healthy individuals and could serve as a future cancer predisposition test.

23 Feb 2011

NanoString launches fixed-panel assay product for human molecular karyotyping

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the first fixed-panel assay product to be developed on its Copy Number Variation detection platform - the nCounter Human Karyotype Panel.

From NanoString Technologies 22 Feb 2011

Macrogen announces formation of Axeq Technologies in the US, Europe and Asia

Macrogen, Inc announces the formation of Axeq Technologies, a US-based division with operations and offices in the US, Europe and Asia. "Axeq" is a premium brand representing a whole new experience and industry-leading standards in DNA sequencing service.

22 Feb 2011

New technique allows early identification of metastasis in women with breast cancer

A quarter of all women who suffer from breast cancer are at risk of metastasis - a recurrence of the cancer. In recent years, researchers at Lund University, Sweden, have developed a technique that can identify in advance which patients belong to this risk group.

22 Feb 2011

Scientists decode DNA of parasitic worm that causes trichinosis

Scientists have decoded the DNA of the parasitic worm that causes trichinosis, a disease linked to eating raw or undercooked pork or carnivorous wild game animals, such as bear and walrus.

20 Feb 2011

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Life Technologies Corporation, today announced Dr. Angel Carracedo and Dr. Mark Pallen as the winners of the European Ion Torrent Personal Genome Machine (PGM™) Sequencer Grants Program.

19 Feb 2011

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Cyclacel Pharmaceuticals, Inc., today announced the publication of preclinical data in the Proceedings of the National Academy of Sciences (PNAS), demonstrating that cyclin E plays a major role in making Human Epidermal growth factor Receptor 2 positive (HER2+) breast cancer resistant to trastuzumab (Herceptin®), a widely used medicine for breast cancer patients who test positive for HER2.

18 Feb 2011

DiaGenic fourth quarter operating revenue increases to NOK 1,078 thousand

DiaGenic has significantly altered its business strategy during 2010 to leverage more effectively its commercial potential, and strengths in Intellectual Property (IP). The Company has made significant progress in its business activities towards big pharma since implementation of the new strategy. DiaGenic is well positioned as a multimodal partner with large pharma and imaging companies.

18 Feb 2011

Two researchers receive Brupbacher Prize for Cancer Research 2011

Today, the Charles Rodolphe Brupbacher Prize for Cancer Research 2011 goes to two researchers who have contributed to better understanding of the genetics underlying the growth of tumors.

17 Feb 2011

Deactivation of CRTC1 protein increases lifespan

Substantial evidence suggests that lifespan is increased if an organism restricts its daily calorie intake, a spartan regime that some say works by just making life seem longer. A team of scientists from the Salk Institute of Biological Studies has discovered a molecular switch flipped by hunger that could not only make longevity more appetizing but identify drug targets for patients with aging-related diseases such as type II diabetes or cancer.

17 Feb 2011

Loss of 'twenty-four' gene makes it harder to wake up

Northwestern University scientists have discovered a new mechanism in the core gears of the circadian clock. They found the loss of a certain gene, dubbed "twenty-four," messes up the rhythm of the common fruit fly's sleep-wake cycle, making it harder for the flies to awaken.

17 Feb 2011

Research: Whole genome sequencing on tumors can treat pancreatic cancer

Whole genome sequencing - spelling out a person's entire DNA genetic code - has moved one step closer to being a medical option for direct patient care.

16 Feb 2011

Researcher discovers mechanism how p53 human genome gets inactivated in cancerous cells

One of the most important genes in the human genome is called p53 and its function is to suppress tumours, according to Roger Leng, a researcher in the Faculty of Medicine & Dentistry. Leng has discovered the mechanism by which p53 is inactivated in cancerous cells, allowing tumours to grow.

15 Feb 2011

Affymetrix introduces NG Class Detergents to advance study of integral membrane proteins

Affymetrix, Inc. today launched its Anatrace® brand Neopentyl Glycol (NG) Class™ Detergents, the next generation of detergents to significantly advance the study of integral membrane proteins (IMPs), the most important proteins found in the human genome.

14 Feb 2011

NHGRI's new strategic plan to identify genetic bases of most single-gene disorders

A new strategic plan from an arm of the National Institutes of Health envisions scientists being able to identify genetic bases of most single-gene disorders and gaining new insights into multi-gene disorders in the next decade. This should lead to more accurate diagnoses, new drug targets and the development of practical treatments for many who today lack therapeutic options, according to the plan from the National Human Genome Research Institute (NHGRI).

14 Feb 2011

Sequencing of whole prostate cancer genomes - an historic development

Today's announcement regarding the sequencing of whole prostate cancer genomes is an historic development in the fight against prostate cancer. The ability to sequence whole genomes will spare some patients from unnecessary treatments and side effects while eliminating an estimated $1.5 billion that is spent each year on overtreatment. The complete research findings will be published in the February 10 issue of Nature.

14 Feb 2011

New study establishes link between coronary artery disease and genetic susceptibility

A new study involving researchers at the Scripps Translational Science Institute and Scripps Health patients reveals major scientific progress in understanding the mechanism of heart disease at the molecular and genomic levels. STSI is an initiative of Scripps Health in collaboration with The Scripps Research Institute.

14 Feb 2011

Genome News and Research

New DNA technology to study cystic fibrosis 'superbug' during infection

Mechanism of cancer treatment related to infertility in women

Researchers to explore genomes of childhood cancers

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

NanoString launches fixed-panel assay product for human molecular karyotyping

Macrogen announces formation of Axeq Technologies in the US, Europe and Asia

New technique allows early identification of metastasis in women with breast cancer

Scientists decode DNA of parasitic worm that causes trichinosis

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

DiaGenic fourth quarter operating revenue increases to NOK 1,078 thousand

Two researchers receive Brupbacher Prize for Cancer Research 2011

Deactivation of CRTC1 protein increases lifespan

Loss of 'twenty-four' gene makes it harder to wake up

Research: Whole genome sequencing on tumors can treat pancreatic cancer

Researcher discovers mechanism how p53 human genome gets inactivated in cancerous cells

Affymetrix introduces NG Class Detergents to advance study of integral membrane proteins

NHGRI's new strategic plan to identify genetic bases of most single-gene disorders

Sequencing of whole prostate cancer genomes - an historic development

New study establishes link between coronary artery disease and genetic susceptibility

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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