Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

Studies show possibility of improving healthcare by tackling problem in standardized way

Given the right equipment, training and skill, an individual surgeon can expect to provide the best possible care on a consistent basis.

1 Dec 2012

CINJ experts available to comment on importance and uses of blood donations

Every two seconds, someone in the United States is in need of blood. According to the American Red Cross, more than 44,000 blood donations are needed each day. With just one donation of a pint of blood, up to three lives can be saved. Nationally, less than 38 percent of the population is eligible to give blood. In New Jersey, according to the state Department of Health fewer than four percent of eligible residents donate regularly, resulting in the critical need for blood donations.

30 Nov 2012

Delaying treatment affects mortality rates among women with breast cancer

Results from a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) show women who wait more than 60 days to begin treatment for advanced breast cancer face significantly higher risks of dying than women who start therapy shortly after diagnosis.

30 Nov 2012

Tdap well tolerated in over-65s

Off-label use of tetanus–diptheria–acellular pertussis vaccine in senior patients results in no more adverse events than the tetanus and diphtheria vaccine, a US study shows.

30 Nov 2012

Lewy pathology out of favor as Parkinson’s culprit

Neurodegeneration and cellular dysfunction may precede the appearance of Lewy bodies in the substantia nigra, shows research that challenges the role of Lewy pathology in Parkinson’s disease.

30 Nov 2012

Diabetes education critical for uncontrolled high blood sugar people with cancer

When people with Type 2 diabetes are diagnosed with cancer -- a disease for which they are at higher risk -- they ignore their diabetes care to focus on cancer treatment, according to new Northwestern Medicine- research. But uncontrolled high blood sugar is more likely to kill them and impairs their immune system's ability to fight cancer.

30 Nov 2012

Combination of chemotherapy and selumetinib shows promise against NSCLC

A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

30 Nov 2012

Eisai announces FDA acceptance of AcipHex NDA for priority review

Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted for priority review Eisai's New Drug Application (NDA) for AcipHex Delayed-Release Sprinkle Capsules 5mg and 10mg for the proposed indication of healing of Gastroesophageal Reflux Disease (GERD), maintenance of healing of GERD and improvement of symptoms of GERD in children 1 to 11 years of age.

30 Nov 2012

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Novartis will highlight more than 140 presentations on key data from its extensive oncology portfolio at the leading year-end scientific meetings devoted to hematology and breast cancer, demonstrating continued innovation in research and development efforts to advance the care of patients with cancer and rare diseases.

30 Nov 2012

Fn14 gene plays a role in growth and spread of non-small cell lung cancer tumors

Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options.

30 Nov 2012

Boehringer Ingelheim announces new data from volasertib Phase I/II leukemia study

Boehringer Ingelheim today announced that new data evaluating volasertib, an investigational polo-like kinase (Plk) inhibitor, will be presented at the 54th American Society of Hematology (ASH) annual meeting taking place December 8-11 in Atlanta, Ga.

30 Nov 2012

DARA BioSciences submits KRN5500 Orphan Drug Application with FDA

DARA BioSciences, Inc., a specialty pharmaceutical company focused on oncology and oncology supportive care products, announced today it has submitted an Orphan Drug Application to the U.S. Food and Drug Administration (FDA) for KRN5500, a compound in development to treat a painful form of chronic chemotherapy-induced peripheral neuropathy (CCIPN).

30 Nov 2012

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

Varian Medical Systems has received regulatory clearance from the Indian Atomic Energy Regulatory Board for the use of its unique TrueBeam High Intensity Mode for advanced radiosurgical treatments.

29 Nov 2012

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).

29 Nov 2012

Combination of blood test and whole-genome sequencing technology could screen cancers

Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.

29 Nov 2012

Blood test and gene sequencing combined to detect cancer

29 Nov 2012

Vermillion’s OVA1 diagnostic test effectively identifies early-stage ovarian cancer

Gynecologic Oncology, the prestigious medical journal of the Society for Gynecologic Oncology, has published the second prospective clinical study of OVA1 which demonstrated the positive performance of the multi-biomarker test in the triage of early-stage ovarian cancer.

29 Nov 2012

Contralateral prophylactic mastectomy does not reduce breast cancer recurrence

About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds.

28 Nov 2012

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Bayer's BAY 86-6150 is being investigated in a Phase II/III study called TRUST (TReatment with Unique recombinant rFVIIa STudy), and the recruitment of the first cohort is now complete.

28 Nov 2012

Oncology News and Research

Further Reading

Children with changes in bully genes have poor survival

Studies show possibility of improving healthcare by tackling problem in standardized way

CINJ experts available to comment on importance and uses of blood donations

Delaying treatment affects mortality rates among women with breast cancer

Tdap well tolerated in over-65s

Lewy pathology out of favor as Parkinson’s culprit

Diabetes education critical for uncontrolled high blood sugar people with cancer

Combination of chemotherapy and selumetinib shows promise against NSCLC

Eisai announces FDA acceptance of AcipHex NDA for priority review

Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting

Fn14 gene plays a role in growth and spread of non-small cell lung cancer tumors

Boehringer Ingelheim announces new data from volasertib Phase I/II leukemia study

DARA BioSciences submits KRN5500 Orphan Drug Application with FDA

Varian's TrueBeam receives Indian AERB clearance for use in advanced radiosurgical treatments

AstraZeneca receives FDA approval for Cometriq to treat medullary thyroid cancer

Combination of blood test and whole-genome sequencing technology could screen cancers

Blood test and gene sequencing combined to detect cancer

Vermillion’s OVA1 diagnostic test effectively identifies early-stage ovarian cancer

Contralateral prophylactic mastectomy does not reduce breast cancer recurrence

Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia

Event guide: 10th CAR-TCR Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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