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Researchers find cause of severe allergic reaction to cetuximab

Clinicians have been perplexed by the fact that some patients given the drug cetuximab - an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer - have a severe and rapid adverse reaction to the drug.

13 Mar 2008

Home test kit confirms men's post-vasectomy sterility

Technology developed at the University of Virginia could soon have a dramatic impact on male contraception practices throughout the U.S. Earlier this year, the U.S. Food and Drug Administration approved SpermCheck Vasectomy, a home test that confirms men's post-vasectomy sterility and is based on discoveries made at U.Va.

12 Mar 2008

Turning off rogue macrophages

University of Pennsylvania scientists studying macrophages, the biological cells that spring from white blood cells to eat and destroy foreign or dying cells, have discovered how these "policemen" differentiate between friend and foe.

12 Mar 2008

Cervarix shows long-term protection from cervical cancer

New data demonstrate that GlaxoSmithKline's cervical cancer candidate vaccine, CERVARIX provides significant protection for women against the four most common cancer- causing human papillomavirus types for nearly six and a half years, the longest duration of protection reported to date.

12 Mar 2008

Anadis licenses antibody technologies from ImmuCell

Anadis Limited, an Australian-based biotechnology company focused on milk derived polyclonal antibodies and other milk-derived bioactives, announced today that it had signed a final agreement with ImmuCell Corporation, a biotechnology company headquartered in Portland, Maine, USA.

11 Mar 2008

Japanese find way to make flu vaccine effective for multiple strains

Japanese scientists say they are well on the way to developing influenza vaccines which are effective for multiple strains of the disease, including strains of the bird flu virus.

11 Mar 2008

Clearer understanding on how allergy symptoms are triggered

A team of Penn State University researchers is the first to demonstrate that lipid molecules in cell membranes participate in mammals' reactions to allergens in a living cell.

10 Mar 2008

Arsenic aids tumor imaging when joined to cancer-homing drug

Arsenic linked to a drug that binds to the blood vessels of cancerous tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancer's response to therapy, researchers at UT Southwestern Medical Center have found.

6 Mar 2008

FDA approves Aloxi injection for prevention of postoperative nausea and vomiting

Eisai Corporation of North America, its U.S. subsidiary, MGI PHARMA, INC., and Helsinn Healthcare SA today announced that the U.S. Food and Drug Administration (FDA) has approved Aloxi (palonosetron hydrochloride) injection for the prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery.

4 Mar 2008

New inexpensive test for malaria detection

ETH Zurich professor Peter Seeberger has been working on a sugar-based malaria vaccine for years.

4 Mar 2008

Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells

Early detection of tumors is one of the Holy Grails of cancer research, an achievement that would greatly improve cancer therapy and prognosis. Two new reports describe different but promising approaches to solving this problem.

3 Mar 2008

Arsenic used to label antibodies for the detection of tumors

3 Mar 2008

New global study of targeted therapies for breast cancer

Two targeted medications designed to treat an aggressive form of breast cancer are being tested in a new study involving 8,000 participants in 50 countries across six continents -- a clinical trial that investigators hope will provide a new model for global cancer research.

1 Mar 2008

Gene expression differences between Europeans and Africans affect response to drugs, infections

Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.

28 Feb 2008

Rresearch may lead to a better flu vaccine

New research from a scientist at the University of Tennessee, Knoxville, has uncovered information that may someday lead to a better flu vaccine.

28 Feb 2008

Scientists devise approach that stops HIV at earliest stage of infection

Their study, which appears this week in the online Early Edition of the Proceedings of the National Academy of Sciences (PNAS), may re-energize attempts to create a preventive/therapeutic vaccine against HIV, say the authors.

28 Feb 2008

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.

28 Feb 2008

Does artificial intelligence help clinicians to recognize atrophic gastritis with thyroid disease?

The association of ABG with thyroid disorders (TD) was first described about 40 years ago.

28 Feb 2008

Nanoemulsion vaccines show increasing promise

A novel technique for vaccinating against a variety of infectious diseases - using an oil-based emulsion placed in the nose, rather than needles - has proved able to produce a strong immune response against smallpox and HIV in two new studies.

27 Feb 2008

Mother's immune system may play role in chilld's autism

The mothers of some autistic children may have made antibodies against their fetuses' brain tissue during pregnancy that crossed the placenta and caused changes that led to autism, suggests research led by Johns Hopkins Children's Center investigators and published in the February issue of the Journal of Neuroimmunology.

26 Feb 2008