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New study on mosquito genome sequences to identify 'transposable elements'

A team of scientists at the University of California, Riverside has begun working on a mosquito research project that, if successful, will provide valuable genetic resources capable of transforming the way mosquito research is conducted around the world.

14 Feb 2011

First evidence of human DNA fragment in bacterial genome

If a human cell and a bacterial cell met at a speed-dating event, they would never be expected to exchange phone numbers, much less genetic material. In more scientific terms, a direct transfer of DNA has never been recorded from humans to bacteria.

14 Feb 2011

People from northern and southern Sweden differ from each other genetically

People from northern and southern Sweden differ from each other genetically, according to the largest genetic study of the Swedish population yet. Swedes also have genetically more in common with Germans and British than with Finns. The study, performed jointly at Karolinska Institutet in Sweden and University of Helsinki, has been published in PLoS ONE.

14 Feb 2011

Genetic map for prostate cancer

Researchers have managed to uncover the whole genetic sequence in prostate cancer. This complete map, hope researchers, will eventually lead to the development of more targeted drugs and a better understanding of which prostate cancers are likely to spread, one of the biggest challenges for physicians and patients.

13 Feb 2011

Genes for prostate cancer mapped for the first time

A genetic blue print that uncovers many of the mutations and genetic damage that drives prostate cancer and could lead to new treatments and better diagnosis has been found. This would mean earlier detection and new breeds of drugs to reverse the damage. Also each patient could have his own “cancer chart” made so that his treatment is personalized. The study, conducted by researchers from the Broad Institute, Dana-Farber Cancer Institute and Weill Cornell Medical College, appears in the Feb. 10 issue of Nature.

13 Feb 2011

Dyadic issued seventh U.S. patent

Dyadic International, Inc., a global biotechnology company focused on the discovery, development, manufacture and sale of enzyme and protein products and solutions for the bioenergy, industrial enzyme and biopharmaceutical industries, announced today that it has been issued U.S. Patent No. 7,883,872 entitled, Construction of Highly Efficient Cellulase Compositions for Enzymatic Hydrolysis of Cellulose, by the United States Patent and Trademark Office ("USPTO").

11 Feb 2011

NIH awards Geospiza phase II SBIR grant to develop new DNA variant application for GeneSifter platform

Geospiza, Inc. the market leading developer of the GeneSifter® software platform for genetic analysis, today announced that the National Human Genome Research Institute of the National Institutes of Health has awarded the company a phase II SBIR grant to collaborate with researchers at Weil Cornell Medical College, Mayo Clinic to develop a new application that quickly identifies and visualizes DNA sequence variations found when comparing normal and cancer tissues using Geospiza's GeneSifter cloud computing platform.

11 Feb 2011

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

The Massachusetts General Hospital research team that first discovered tumor-associated RNA in tiny membrane-enclosed sacs released into the bloodstream by cancer cells has now found that these microvesicles also contain segments of tumor DNA, including retrotransposons - also called "jumping genes" - that copy and insert themselves into other areas of the genome.

10 Feb 2011

Full genetic blueprint of multiple prostate tumors laid bare

For the first time, researchers have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease. The study, made possible by key advances in whole genome sequencing and analysis, points to several new prostate cancer genes and a critical category of genomic changes as important drivers of prostate cancer growth.

10 Feb 2011

Scientists develop novel approach to detect long-distance chromosomal interactions for CAD

The discovery that a "gene desert" on chromosome 9 was a hotspot for coronary artery disease (CAD) risk was among the highlights of findings produced recently by genome-wide association studies, which compare the genomes of many people for genetic variations and have been broadly used in the past few years to study hundreds of diseases and complex traits. Gene deserts are large genomic segments devoid of genes.

10 Feb 2011

Human-worm connection research provides insight into brain development, diseases

"Man is but a worm" was the title of a famous caricature of Darwin's ideas in Victorian England. Now, 120 years later, a molecular analysis of mysterious marine creatures unexpectedly reveals our cousins as worms, indeed.

10 Feb 2011

Johns Hopkins funds 12 research groups to launch new BSi program on cognitive disorders

The Johns Hopkins Brain Sciences Institute has funded a total of $5 million to 12 different research groups at Hopkins to launch the new Synapses, Circuits and Cognitive Disorders Program. The new BSi program aims to understand the fundamentals of brain function by focusing on the synapse — the point of contact between two nerve cells — to better understand cognitive disorders.

9 Feb 2011

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

Unprecedented single molecule imaging movies of living cell membranes, taken by a research team based at Kyoto University and the University of New Mexico, have clarified a decades-old enigma surrounding receptor molecule behaviors. The results, appearing in the latest issue of the Journal of Cell Biology, promise to open the door to new possibilities for drug development.

9 Feb 2011

SwitchGear Genomics, BioCat enter distribution agreement for LightSwitch Luciferase Assay System in Europe

SwitchGear Genomics Inc., a leading provider of products for studying the regulatory elements in the human genome, today announced that the company signed an agreement for BioCat GmbH to distribute the innovative LightSwitch Luciferase Assay System™ in Europe.

9 Feb 2011

Munich research team provides promising alternative to DNA-based procedures

Defects in the genome are the cause of many diseases. Gene therapy - direct replacement of mutant genes by intact DNA copies - offers a means of correcting such defects. Now a research team based at the Medical Center of the University of Munich, and led by Privatdozent Dr. Carsten Rudolph, has taken a new approach that avoids DNA delivery.

8 Feb 2011

The Lancet journal publishes BENLYSTA BLISS-52 study against SLE

Human Genome Sciences, Inc. and GlaxoSmithKline PLC today announced publication of the BLISS-52 study of BENLYSTA in autoantibody-positive patients with active systemic lupus erythematosus in The Lancet.

7 Feb 2011

Genomic study identifies link between Native American ancestry, relapse in young leukemia patients

The first genome-wide study to demonstrate an inherited genetic basis for racial and ethnic disparities in cancer survival linked Native American ancestry with an increased risk of relapse in young leukemia patients. The work was done by investigators at St. Jude Children's Research Hospital and the Children's Oncology Group.

6 Feb 2011

Researchers discover molecular mechanism implicated in geographic atrophy

A team of researchers, led by University of Kentucky ophthalmologist Dr. Jayakrishna Ambati, has discovered a molecular mechanism implicated in geographic atrophy, the major cause of untreatable blindness in the industrialized world.

6 Feb 2011

Researchers describe the complete genome of Daphnia

From an environmental perspective, Daphnia pulex -- the waterflea - is the best-studied organism on the planet. Scientists know how this species responds to pollution, predators, day and night, making it an important model for ecological and evolutionary research. Its genome, however, remained elusive, limiting understanding of how the environment and genes interact.

5 Feb 2011

Researchers find RIPs remain active, continue to produce new insertions in human genome

An ambitious hunt by Johns Hopkins scientists for actively "jumping genes" in humans has yielded compelling new evidence that the genome, anything but static, contains numerous pesky mobile elements that may help to explain why people have such a variety of physical traits and disease risks.

5 Feb 2011

Genome News and Research

New study on mosquito genome sequences to identify 'transposable elements'

First evidence of human DNA fragment in bacterial genome

People from northern and southern Sweden differ from each other genetically

Genetic map for prostate cancer

Genes for prostate cancer mapped for the first time

Dyadic issued seventh U.S. patent

NIH awards Geospiza phase II SBIR grant to develop new DNA variant application for GeneSifter platform

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

Full genetic blueprint of multiple prostate tumors laid bare

Scientists develop novel approach to detect long-distance chromosomal interactions for CAD

Human-worm connection research provides insight into brain development, diseases

Johns Hopkins funds 12 research groups to launch new BSi program on cognitive disorders

Single molecule imaging movies of living cell membranes clarify enigma surrounding receptor molecule behaviors

SwitchGear Genomics, BioCat enter distribution agreement for LightSwitch Luciferase Assay System in Europe

Munich research team provides promising alternative to DNA-based procedures

The Lancet journal publishes BENLYSTA BLISS-52 study against SLE

Genomic study identifies link between Native American ancestry, relapse in young leukemia patients

Researchers discover molecular mechanism implicated in geographic atrophy

Researchers describe the complete genome of Daphnia

Researchers find RIPs remain active, continue to produce new insertions in human genome

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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