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New study may help improve walking capacity in people with multiple sclerosis

Significant gaps in how walking capacity and performance is assessed for people with Multiple Sclerosis (MS) could be harming therapy and treatment development according to McGill University researchers.

3 Nov 2020

Scientists identify neutralizing human monoclonal antibodies against SARS-CoV-2

University of Pittsburgh School of Medicine scientists have discovered the fastest way to identify potent, neutralizing human monoclonal antibodies against SARS-CoV-2, the virus that causes COVID-19.

3 Nov 2020

Researchers reveal mechanisms that help C. difficile pathogen to survive in low oxygen levels

Researchers from ITQB NOVA, in collaboration with the Institut Pasteur in Paris, have shed light on the mechanisms that allow Clostridioides difficile, a pathogen that can only grow in oxygen-free environments, to be able to survive low oxygen levels.

3 Nov 2020

Global collaboration provides a COVID-19 disease map

A collaboration of researchers from 120 different institutes across 30 countries including France, Germany, Australia, Japan, USA, India, Turkey, Brazil, and Canada initiated an effort to develop a COVID-19 Disease Map - a collection of computational models and diagrams of molecular mechanisms implicated in COVID-19.

2 Nov 2020

Drug combo for Type 2 diabetes continues to stay effective after two years of treatment

Patients with Type 2 diabetes often take metformin as first-line therapy to help stabilize their blood glucose.

2 Nov 2020

Two studies find age as a primary factor in melanoma treatment resistance

Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.

2 Nov 2020

Channel 7 grants fund new projects focusing on care for homeless children

Nurse practitioners working with social service agencies is one way to help the estimated 22% of Australian children living in temporary or precarious conditions, with families hit hard by unemployment and other problems created by the pandemic.

2 Nov 2020

People who experience high blood pressure while sleeping have increased risk of heart attacks, strokes

People who experience high blood pressure while sleeping are more likely to experience future cardiovascular disease especially heart failure, even when their daytime blood pressure is within normal ranges, according to new research published today in the American Heart Association's flagship journal Circulation.

2 Nov 2020

Researchers develop a unique method of identifying early signs of acute kidney injury

Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI).

2 Nov 2020

5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro

Researchers tested 5-amino levulinic acid in vitro in human-derived cells and found it prevents severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Because it is safe and ubiquitous in plants and animals, it could be a potential drug against SARS-CoV-2.

1 Nov 2020

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

The same biochemical triggers that spur a "fight or flight" response when we encounter threats may help tumor cells to thrive.

30 Oct 2020

SARS-CoV-2 virus may target red marrow and prevent the formation of new erythrocytes

Specialists from the Department of Fundamental Medicine of Far Eastern Federal University (FEFU) with Russian and Japanese colleagues have probed into mechanisms of COVID-19 inside-the-body distribution linked to erythrocytes damaging.

30 Oct 2020

Researchers report a novel approach to generate T-cells faster

Adoptively transferred T-cells can prolong survival and sometimes cure patients with advanced solid tumors. While promising, it can take months to generate the necessary T-cells to help these patients. Such slow speed makes this therapy impractical for most patients who need immediate treatment.

30 Oct 2020

Study identifies new cause of inflammation in people living with HIV

While current antiretroviral treatments for HIV are highly effective, data has shown that people living with HIV appear to experience accelerated aging and have shorter lifespans - by up to five to 10 years - compared to people without HIV.

30 Oct 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin Group 30 Oct 2020

Research projects receive BTCA grants to develop novel drugs for various diseases

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

30 Oct 2020

Massey Cancer Center and VCUarts win Hamilton International Arts in Health Award

Last year, 12 patients in the Supportive Care Clinic at VCU Massey Cancer Center stepped inside a conference room, donned motion sensors and engaged in a facilitated life review, acting out various parts of their lives through a virtual avatar displayed on a projection screen.

30 Oct 2020

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

Now, a team of researchers at the University of Florida report that the SARS-CoV-2 viroporin triggers the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome, which is responsible for the inflammatory pathology in severely ill COVID-19 patients.

30 Oct 2020

MD65 IgG-YTE shows powerful post-exposure neutralization of SARS-CoV-2

A recent study published in the preprint server bioRxiv in October 2020 describes a reliable animal model to demonstrate the powerful capacity of human neutralizing mAbs directed against SARS-CoV-2 to prevent viral binding the host cell receptor and thus block infection. This indicates the lifesaving value of mAbs in severe COVID-19.

29 Oct 2020

Therapy News and Research

New study may help improve walking capacity in people with multiple sclerosis

Scientists identify neutralizing human monoclonal antibodies against SARS-CoV-2

Researchers reveal mechanisms that help C. difficile pathogen to survive in low oxygen levels

Global collaboration provides a COVID-19 disease map

Drug combo for Type 2 diabetes continues to stay effective after two years of treatment

Two studies find age as a primary factor in melanoma treatment resistance

Channel 7 grants fund new projects focusing on care for homeless children

People who experience high blood pressure while sleeping have increased risk of heart attacks, strokes

Researchers develop a unique method of identifying early signs of acute kidney injury

5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

SARS-CoV-2 virus may target red marrow and prevent the formation of new erythrocytes

Researchers report a novel approach to generate T-cells faster

Study identifies new cause of inflammation in people living with HIV

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Research projects receive BTCA grants to develop novel drugs for various diseases

Massey Cancer Center and VCUarts win Hamilton International Arts in Health Award

SARS-CoV-2 viroporin triggers NLRP3 inflammasome causing a severe inflammatory response

MD65 IgG-YTE shows powerful post-exposure neutralization of SARS-CoV-2

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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