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Study shows why young, female patients have low response rates to cancer immunotherapy

Cancer immunotherapy -- empowering a patient's own immune system to clear away tumors on its own -- holds great promise for some patients. But for other patients, immunotherapy just doesn't work.

18 Aug 2020

Non-sustained research on emerging infectious diseases endangers pandemic responses

Lack of Continuing Research Into Infectious Disease Epidemics Endangers Pandemic Responses, According to Ben-Gurion University Researchers

18 Aug 2020

Other forms of treatments are as effective as opioids for acute musculoskeletal injuries

Two new evidence reviews related to acute musculoskeletal injuries like strains and sprains suggest other forms of treatments are as effective as opioids and have less risk of harms to patients.

18 Aug 2020

A wearable sensor printed on natural polymer for monitoring body fluids present in sweat

A wearable sensor printed on microbial nanocellulose, a natural polymer, has been created in Brazil by researchers at the University of São Paulo in São Carlos in collaboration with colleagues at São Paulo State University in Araraquara, the University of Araraquara, the University of Campinas, and the Brazilian National Nanotechnology Laboratory.

17 Aug 2020

Researchers may have discovered the key to treating inflammatory diseases

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

17 Aug 2020

Novel receptor protein may hold promise for treating COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

17 Aug 2020

New insights into how the brain's internal states influence decision-making

Biomedical Engineering's Matthew Smith and Byron Yu, along with former Ph.D. student Ben Cowley (School of Computer Science '18), have studied the neural basis through which internal states in the brain affect decision-making over an extended period of time.

17 Aug 2020

Hydroxychloroquine is not a possible defense against COVID-19, study shows

Researchers at Case Western Reserve University have added to the growing body of understanding about how hydroxychloroquine (HCQ) is not a possible defense against COVID-19.

17 Aug 2020

Study reveals bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

17 Aug 2020

FDA approves drug for treatment of neuromyelitis optica spectrum disorder

The U.S. Food and Drug Administration has approved Enspryng (satralizumab-mwge) for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adults with a particular antibody - patients who are anti-aquaporin-4 or AQP4 antibody-positive.

17 Aug 2020

Deciphering the largest CRISPR system

Professor Guillermo Montoya spoke to News-Medical on his research that involved visualizing the largest and most complex CRISPR system.

17 Aug 2020

Back-pain patients taking opioid painkillers produce anti-opioid antibodies

University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies.

17 Aug 2020

New test provides information on immune response to Sars-Cov-2 in transplant patients

Even patients with suppressed immune systems can achieve a strong immune response to Sars-Cov-2. A test helps to adapt therapy following an infection.

17 Aug 2020

Potency-enhancing drugs show ability to improve prognosis in patients with colorectal cancer

A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer.

17 Aug 2020

New type of immunotherapy extends survival of mice with triple negative breast tumors

Immunotherapies for cancer - treatments that prime the immune system to attack tumors - are valuable weapons in the anti-cancer arsenal. But some cancers are more difficult to target with this strategy than others.

17 Aug 2020

Startling report suggests COVID-19 may have first appeared in 2012

Now, a report on the website Independent Science News by researchers Jonathan Latham, and Allison Wilson suggests that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), may not have originated at a Wuhan wet market in 2019, but 1,000 miles away in 2012, in a Chinese mineshaft where workers fell ill with a mysterious, pneumonia-like illness after being exposed to bats.

17 Aug 2020

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause disease and death in many countries even today. At present, there is no effective treatment. A recent study published on the preprint server bioRxiv in August 2020 reports the potential of a new class of drugs called CAR NK cells, which could be used off-the-shelf to treat this disease.

17 Aug 2020

Potential inhibitors of SARS-CoV-2 identified

Now, a new study published on the preprint server bioRxiv in August 2020 reports the discovery of two inhibitors of the helicase enzyme, which is essential for viral replication and the most highly conserved non-structural coronavirus (CoV) protein.

16 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

Multiphase program provides valuable lessons for advancing the fight against malaria

The intensive implementation of currently available tools to fight malaria can achieve a drastic reduction in disease burden, but is not enough to interrupt its transmission.

15 Aug 2020

Drugs News and Research

Study shows why young, female patients have low response rates to cancer immunotherapy

Non-sustained research on emerging infectious diseases endangers pandemic responses

Other forms of treatments are as effective as opioids for acute musculoskeletal injuries

A wearable sensor printed on natural polymer for monitoring body fluids present in sweat

Researchers may have discovered the key to treating inflammatory diseases

Novel receptor protein may hold promise for treating COVID-19

New insights into how the brain's internal states influence decision-making

Hydroxychloroquine is not a possible defense against COVID-19, study shows

Study reveals bacteria's secret weapon to evade immune responses

FDA approves drug for treatment of neuromyelitis optica spectrum disorder

Deciphering the largest CRISPR system

Back-pain patients taking opioid painkillers produce anti-opioid antibodies

New test provides information on immune response to Sars-Cov-2 in transplant patients

Potency-enhancing drugs show ability to improve prognosis in patients with colorectal cancer

New type of immunotherapy extends survival of mice with triple negative breast tumors

Startling report suggests COVID-19 may have first appeared in 2012

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

Potential inhibitors of SARS-CoV-2 identified

ARDS may not be the primary lung iInjury in COVID-19

Multiphase program provides valuable lessons for advancing the fight against malaria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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