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H3 Biomedicine introduces cancer research and development operations in Cambridge

H3 Biomedicine today announced that it has launched research and development operations in Cambridge, Massachusetts. H3 Biomedicine will undertake a comprehensive approach to breakthrough oncology treatments based on two primary principles: 1) the genetics of patients' cancers can reveal drug targets tailored to their cancers and 2) the advances in modern chemistry enable the discovery of new classes of safe and effective drugs against these targets.

27 Jan 2011

NuGEN, Caliper enter co-marketing agreement in next generation sequencing sample preparation methods

NuGEN Technologies, Inc. and Caliper Life Sciences, Inc. today announced a co-marketing agreement for the development of automated methods for next generation sequencing sample preparation on Caliper's Sciclone® NGS Workstation.

27 Jan 2011

NuGEN expands NGS utility for microbial transcriptome analysis with Ovation Prokaryotic RNA-Seq System

NuGEN Technologies, a leader in genomics sample preparation, expands the utility of next-generation sequencing for the analysis of microbial species and microbiome samples with its Ovation Prokaryotic RNA-Seq System.

27 Jan 2011

Next generation sequencing on the European growth path: Report

Next Generation Sequencers have found their way into service providing labs and the global biomedical research community. 2010 has seen a serious uptake of Next Generation Sequencing technology, and today it is perceived as an indispensable tool.

26 Jan 2011

Realignment with participants' interest important for future of genomic research

Obtaining consent for genetic studies can be an opportunity for researchers to foster respectful engagement with participants, not merely to mitigate legal risk. This shift is proposed in a policy forum appearing tomorrow, Jan. 21, in Science, the journal of the American Academy for the Advancement of Science.

25 Jan 2011

Tufts University calls for strategic approach to teach genomic testing in medical school

Genetics in Medicine, the official journal of the American College of Medical Genetics, published this month a paper by Tufts University faculty calling for a moderate, strategic approach to teaching personalized genomic testing in medical school curricula.

25 Jan 2011

Cellectis to launch gene specific TAL nucleases

Cellectis bioresearch, a specialist in genome customization and a subsidiary of Cellectis, has today announced that it will launch gene specific TAL nucleases on February 28, 2011.

25 Jan 2011

University of California study may shed light on human ability to adapt hypoxia

In an important study that may shed light on human ability to adapt to hypoxia, or inadequate levels of oxygen, researchers at the University of California, San Diego School of Medicine have proven that the genome of flies exposed to long-term hypoxia are changed to permanently affect gene expression.

24 Jan 2011

Functional tests are necessary to understand human disease despite genetic sequencing

Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand the biological relevance of the results of sequencing studies as they relate to disease, using a suite of diseases known as the ciliopathies which can cause patients to have many different traits.

24 Jan 2011

Major breakthrough: Genome-based medicine for treatment of alcoholism

For the first time in alcohol addiction research, UVA investigators have successfully treated alcohol-dependent individuals with medication that is tailored specifically to match their genetic profile.

21 Jan 2011

Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

Fat appears to associate with some distinctive chemical changes in the DNA - a finding that may help explain why obesity can increase the risk for chronic problems such as cardiovascular disease and diabetes, researchers report.

21 Jan 2011

Researchers take systematic approach to catalog factors that control blood cell development

A small pool of stem cells replenishes the human body with about 200 billion new blood cells daily. But the elaborate circuitry that determines if a cell will develop into a T cell, red blood cell, or one of the nine or more other blood cell types remains largely unknown. A research team led by scientists from the Broad Institute and Brigham and Women's Hospital has taken a systematic approach to help decipher this circuitry, compiling a comprehensive catalog of the factors that determine a blood cell's fate.

21 Jan 2011

Researchers believe driver mutations promote development, growth of prostate cancer

Prostate cancer is known to occur typically in older men. Yet some patients are younger than 50 years at the time of diagnosis. Scientists assume that these cases might be the key to understanding the biology of this disease. Early prostate cancer might be a subtype which is characterized by a relatively small number of genetic modifications.

21 Jan 2011

Scientists decipher genetic code for a pancreatic cancer type

Scientists at Johns Hopkins have deciphered the genetic code for a type of pancreatic cancer, called neuroendocrine or islet cell tumors. The work, described online in the Jan. 20 issue of Science Express, shows that patients whose tumors have certain coding "mistakes" live twice as long as those without them.

21 Jan 2011

Genetic expression can be modified with natural substances to prevent chronic illness

Research findings demonstrating how genetic expression can be modified with natural substances to prevent chronic illness was the topic of an address by Jeffrey Bland, Ph.D., FACN, FACB, at the 8th Annual Scripps Center for Integrative Medicine 2011 conference in San Diego, California, January 13 - 16.

20 Jan 2011

OSC and RINCH offer support to speed discovery techniques of childhood diseases

Worried about her high fever and severe abdominal pain, a young couple rushed their baby daughter to the emergency department of Nationwide Children's Hospital. Physicians there found a lump in her belly, and, after examining X-rays and blood work, confirmed the parents' worst fear: their 18-month-old little girl had neuroblastoma, a rare pediatric cancer that involves the adrenal glands.

20 Jan 2011

Koronis' KP-1461 drug causes extra mutations to occur in HIV genome in HIV-infected patients

Recently published Phase 2a clinical trial results show that the frequency of specific, drug-induced mutations in the HIV genome can be significantly increased by administering KP-1461, a drug being developed by Koronis Pharmaceuticals based on its novel Viral Decay Acceleration (VDA) drug mechanism.

20 Jan 2011

University of Minnesota grants Cellectis rights related to TAL effector-mediated DNA recognition and cleavage

Cellectis, the French genome engineering specialist, has announced today that it has signed an exclusive license agreement with the University of Minnesota that grants Cellectis the worldwide right to use inventions related to TAL effector-mediated DNA recognition and cleavage. This revolutionary approach for the targeted modification of genomes was developed by the University of Minnesota and Iowa State University.

20 Jan 2011

Scarab Genomics, WIST enter research agreement to produce isoprene from paper, pulp mill waste streams

Scarab Genomics, a leader in the development of production E. coli strains based on reduced genome technology and the Wisconsin Institute for Sustainable Technology at the University of Wisconsin-Stevens Point have entered into a research agreement to produce isoprene from paper and pulp mill waste streams.

20 Jan 2011

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

In a collaborative project involving scientists from three continents, researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer.

20 Jan 2011

Genome News and Research

H3 Biomedicine introduces cancer research and development operations in Cambridge

NuGEN, Caliper enter co-marketing agreement in next generation sequencing sample preparation methods

NuGEN expands NGS utility for microbial transcriptome analysis with Ovation Prokaryotic RNA-Seq System

Next generation sequencing on the European growth path: Report

Realignment with participants' interest important for future of genomic research

Tufts University calls for strategic approach to teach genomic testing in medical school

Cellectis to launch gene specific TAL nucleases

University of California study may shed light on human ability to adapt hypoxia

Functional tests are necessary to understand human disease despite genetic sequencing

Major breakthrough: Genome-based medicine for treatment of alcoholism

Fat linked with DNA chemical changes may help identify risk of cardiovascular disease, diabetes

Researchers take systematic approach to catalog factors that control blood cell development

Researchers believe driver mutations promote development, growth of prostate cancer

Scientists decipher genetic code for a pancreatic cancer type

Genetic expression can be modified with natural substances to prevent chronic illness

OSC and RINCH offer support to speed discovery techniques of childhood diseases

Koronis' KP-1461 drug causes extra mutations to occur in HIV genome in HIV-infected patients

University of Minnesota grants Cellectis rights related to TAL effector-mediated DNA recognition and cleavage

Scarab Genomics, WIST enter research agreement to produce isoprene from paper, pulp mill waste streams

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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