Immune System News and Research

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IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Plasma cells play a key role in our immune system. Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function.

20 Jan 2016

Animal antibodies help identify diseased cells during immunohistology procedures

We all know it from biology lessons at school: Antibodies help us to ward off disease and are essential components of our immune system. What many people do not know is that physicians and scientists use animal antibodies to identify diseased or mutated cells.

20 Jan 2016

New technique may accelerate development of novel vaccines

An interdisciplinary team of Oxford University researchers has devised a new technique to speed up the development of novel vaccines.

20 Jan 2016

PD-L1 inhibition well-tolerated, active in metastatic RCC

The programmed death-ligand 1 inhibitor atezolizumab has a favourable toxicity profile and shows anti-tumour activity in previously treated patients with metastatic renal cell carcinoma, according to phase Ia trial findings.

19 Jan 2016

TG4010 vaccine promising in advanced NSCLC

Addition of the TG4010 vaccine to first-line chemotherapy improves outcomes in patients with advanced non-small-cell lung cancer, show the results of a placebo controlled trial.

19 Jan 2016

First patients treated in Phase 1b trial of pembrolizumab with REOLYSIN in advanced pancreatic adenocarcinoma

Oncolytics Biotech Inc. today announced that the first patients have been treated in a Phase 1b study of pembrolizumab (KEYTRUDA) in combination with REOLYSIN (pelareorep) and chemotherapy in patients with advanced pancreatic adenocarcinoma (REO 024).

19 Jan 2016

New clinical imaging method may enable doctors to tackle lung infections

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

19 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

Innovative OPW program offers wellness services to improve work lives of HCMC providers

For many professions, finding the right balance between work schedules and home life can be challenging. Health care providers are not immune to this issue. In fact, stress and burnout are prevalent in the medical field and if left unaddressed, can affect both providers and patients.

19 Jan 2016

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

We've all seen the headlines. "Man found to be shedding virulent strain of polio"; "Virulent flu strain in Europe hits the economy"; "Most virulent strain of E. coli ever seen contains DNA sequences from plague bacteria."

19 Jan 2016

Scientists develop wireless brain sensors

A team of neurosurgeons and engineers has developed wireless brain sensors that monitor intracranial pressure and temperature and then are absorbed by the body, negating the need for surgery to remove the devices.

18 Jan 2016

UConn-led researchers identify specific gene linked to Hajdu-Cheney syndrome

Fragile bones are usually an old person's affliction, but sometimes children are born with them. Now, a team of researchers led by UConn professor Ernesto Canalis has shown in mice that a specific gene can cause the disease, called Hajdu-Cheney syndrome. Overabundant bone-absorbing cells may be causing the disorder's characteristic bone loss, and the researchers hope to find a potential treatment.

18 Jan 2016

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Health Canada recently approved, for the first time in Canada, a clinical project for a Phase I study aimed at treating lymphomas associated with the Epstein-Barr virus (EBV) through adoptive cellular immunotherapy that is specific to EBV.

18 Jan 2016

Study explores new approaches to prevent fall asthma exacerbations in pediatric patients

Experts from Children's Hospital Colorado (Children's Colorado) co-led a team of researchers in studying new approaches to reducing fall asthma exacerbations in pediatric patients.

18 Jan 2016

Quad partners with University of Massachusetts to evaluate performance of novel cell separation solution

The rapid growth of cell-based immunotherapy research has led to an increase in demand for methods to isolate specific immune cell populations from heterogeneous samples with high viability, purity and recovery efficiency. Quad Technologies ("Quad"), is meeting this need with its MagCloudz™ Streptavidin Cell Separation Kits and has partnered with The University of Massachusetts Medical School to evaluate the performance of its novel cell separation solution for the enrichment and purification of CD3+ T-cells from human umbilical cord blood.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

Researchers identify origins of aggressive childhood lymphoma

The origins of a type of aggressive childhood lymphoma have been found, giving hope that new drugs could be designed to prevent the disease coming back after treatment.

18 Jan 2016

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

The cancer drug paclitaxel just got more effective. For the first time, researchers from the University of North Carolina at Chapel Hill have packaged it in containers derived from a patient's own immune system, protecting the drug from being destroyed by the body's own defenses and bringing the entire payload to the tumor.

18 Jan 2016

MUSC starts enrolling participants in clinical trial to evaluate two drugs for non-small cell lung cancer

In an international first, people with lung cancer will find out if a new combination of drugs can kick-start their bodies' ability to fight back against the disease. They'll be part of a clinical trial now enrolling participants at the Medical University of South Carolina.

18 Jan 2016

Scientists identify origins of anaplastic large cell lymphoma

Anaplastic large cell lymphoma (ALCL) is a very aggressive cancer of the blood, which usually occurs as a tumour in lymph nodes, the skin, the lungs, the liver, and in soft tissue, and mainly affects children and young adults.

18 Jan 2016

Immune System News and Research

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Animal antibodies help identify diseased cells during immunohistology procedures

New technique may accelerate development of novel vaccines

PD-L1 inhibition well-tolerated, active in metastatic RCC

TG4010 vaccine promising in advanced NSCLC

First patients treated in Phase 1b trial of pembrolizumab with REOLYSIN in advanced pancreatic adenocarcinoma

New clinical imaging method may enable doctors to tackle lung infections

Researchers identify protein structure linked to pain and heat perception

Innovative OPW program offers wellness services to improve work lives of HCMC providers

Antivirulence antibiotics could evade resistance longer than traditional antibiotics

Scientists develop wireless brain sensors

UConn-led researchers identify specific gene linked to Hajdu-Cheney syndrome

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Study explores new approaches to prevent fall asthma exacerbations in pediatric patients

Quad partners with University of Massachusetts to evaluate performance of novel cell separation solution

Scientists find new way to re-engineer body’s immune system to target cancer

Researchers identify origins of aggressive childhood lymphoma

Anti-cancer drug uses 50 times less chemo to effectively destroy drug-resistant lung cancer

MUSC starts enrolling participants in clinical trial to evaluate two drugs for non-small cell lung cancer

Scientists identify origins of anaplastic large cell lymphoma

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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