Immune System News and Research

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New drug screening method may predict treatment options for patients with multiple myeloma

A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer. The process, developed by scientists at Washington University School of Medicine in St. Louis, also may aid patients with leukemia or lymphoma.

21 Nov 2015

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Ninlaro (ixazomib) in combination with two other therapies to treat people with multiple myeloma who have received at least one prior therapy.

21 Nov 2015

Roundworm infection increases fertility among women in the Amazon

Parasitic worms can live inside humans gaining nourishment from the food we ingest (roundworms) or from our blood (hook worms), whilst being safe from predators. Although roundworm infections are generally symptomless they are not something any of us would choose to have. However, it has recently been found that infection with roundworm increases a woman's fertility.

20 Nov 2015

Health experts urge lawmakers, regulators to close loopholes in Orphan Drug Act

Health experts at Johns Hopkins Medicine are calling on lawmakers and regulators to close loopholes in the Orphan Drug Act they claim give drug companies millions of dollars in unintended and misplaced subsidies and tax breaks and fuel skyrocketing medication costs.

20 Nov 2015

Interaction between two brain proteins has substantial effect on memory formation

In a new study that could have implications for future drug discovery efforts for a number of neurodegenerative diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that the interaction between a pair of brain proteins has a substantial and previously unrecognized effect on memory formation.

20 Nov 2015

New injectable 'biogel' may become new weapon against cancer

A new injectable "biogel" is effective in delivering anti-cancer agents directly into cancerous tumours and killing them. This technology, developed by researchers at the University of Montreal Hospital Research Centre, has already been successfully tested in the laboratory. If it works in patients, the therapy could one day revolutionize treatment for many forms of cancer.

20 Nov 2015

Loyola professor receives prestigious 2015 Marion Spencer Fay Award

Loyola University Chicago Professor Katherine L. Knight, PhD, one of the nation's leading immune system researchers, has received the prestigious 2015 Marion Spencer Fay Award.

20 Nov 2015

TSRI researchers awarded $1.6 million grant to advance preclinical studies of potential heroin vaccine

Now researchers at The Scripps Research Institute have been awarded a prestigious Translational Avant-Garde Award, which supports the development of medications for substance abuse disorders, from the National Institutes of Health National Institute on Drug Abuse.

20 Nov 2015

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

It's a fairly common genetic condition that can surface as a series of dark skin spots and result in a host of maladies from tumors to premature cardiovascular disease. Medical College of Georgia researchers hope their studies of how neurofibromatosis 1, or NF1, can dangerously thicken or thin blood vessel walls will one day help physicians better identify and treat these young patients at cardiovascular risk.

20 Nov 2015

Simple blood test may predict speed of recovery from postoperative pain and dysfunction

A simple blood test taken before surgery may predict how quickly patients recover from their procedure, suggests a new study in the December issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists.

20 Nov 2015

Research findings may lead to potential therapeutic target for treating inflammatory bowel diseases

UT Southwestern Medical Center researchers have shown that a pathogen-sensing molecule plays a vital role in keeping gastrointestinal (GI) systems healthy.

20 Nov 2015

BUSM researchers identify new fingerprint of inflammation in obesity-associated type 2 diabetes

There is strong evidence that inflammation promotes obesity-associated type 2 diabetes and diabetes complications. However, clinical trials with anti-inflammatory drugs have only been modestly effective for treating Type 2 diabetes. A new fingerprint of inflammation that may be able to predict which patients with obesity may also develop type 2 diabetes has been identified by Boston University School of Medicine researchers.

19 Nov 2015

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC).

19 Nov 2015

INP achieves 80% survival rate in acute lymphoblastic leukemia patients

The National Institute of Pediatrics in Mexico, has achieved 80 percent survival rate in patients with acute lymphoblastic leukemia, a major oncological illness that affects children.

19 Nov 2015

Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

Men are twice as likely as women to develop Parkinson's disease, a nervous system disorder characterized by tremors and difficulty moving. New research to be presented at Cardiovascular, Renal and Metabolic Diseases: Physiology and Gender suggests that the difference in risk may be due to the presence of the male sex hormone testosterone.

19 Nov 2015

New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, West Africa and in the US, according to a study published in the latest issue of the journal Lancet Infectious Disease.

19 Nov 2015

Gamma interferon may have potential to prevent Ebola infection

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

18 Nov 2015

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer.

18 Nov 2015

Novel immunotherapeutic approach could improve outcomes for patients with advanced bladder cancer

Noguchi explained that immunotherapy has emerged recently as a viable and attractive strategy for the treatment of advanced cancer.

18 Nov 2015

Immune System News and Research

New drug screening method may predict treatment options for patients with multiple myeloma

Ninlaro (ixazomib) approved to treat people with multiple myeloma

Roundworm infection increases fertility among women in the Amazon

Health experts urge lawmakers, regulators to close loopholes in Orphan Drug Act

Interaction between two brain proteins has substantial effect on memory formation

New injectable 'biogel' may become new weapon against cancer

Loyola professor receives prestigious 2015 Marion Spencer Fay Award

TSRI researchers awarded $1.6 million grant to advance preclinical studies of potential heroin vaccine

MCG researchers explore how neurofibromatosis puts young patients at risk for cardiovascular disease

Simple blood test may predict speed of recovery from postoperative pain and dysfunction

Research findings may lead to potential therapeutic target for treating inflammatory bowel diseases

BUSM researchers identify new fingerprint of inflammation in obesity-associated type 2 diabetes

Lilly, Merck expand oncology clinical trial collaboration

INP achieves 80% survival rate in acute lymphoblastic leukemia patients

Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

New technique improves accuracy of CRISPR/Cas9 gene editing system

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

Gamma interferon may have potential to prevent Ebola infection

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Novel immunotherapeutic approach could improve outcomes for patients with advanced bladder cancer

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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