Immune System News and Research

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Low vitamin D levels may limit effectiveness of HIV treatment

A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults.

18 Nov 2015

UCLA researchers find new way to reduce ascites with minimal side effects

Women who have ovarian cancer often develop a condition called ascites, which is a buildup of fluids in the abdomen. The most common treatment for ascites is puncturing the abdomen and manually draining the fluid, which is painful and risky and must be repeated every few weeks.

18 Nov 2015

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

TSRI researchers have new weapons to combat HIV

Scientists at The Scripps Research Institute have new weapons in the fight against HIV. Their new study, published November 17, 2015 as the cover article of the journal Immunity, describes four prototype antibodies that target a specific weak spot on the virus. Guided by these antibodies, the researchers then mimicked the molecular structure of a protein on HIV when designing their own potential HIV vaccine candidate.

18 Nov 2015

NSU collaborates with Karolinska Institutet to conduct cell-based biomedical research

Nova Southeastern University is now at the forefront of conducting pioneering cell-based biomedical research with the launch of the new NSU Cell Therapy Institute, an international collaboration with prominent medical research scientists from Sweden's world-renowned Karolinska Institutet (KI).

17 Nov 2015

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Immune Pharmaceuticals Inc. announced today that the first patient has been enrolled into the Phase 2 clinical trial evaluating the safety and efficacy of its first in class fully human monoclonal antibody, bertilimumab in Ulcerative Colitis (UC).

17 Nov 2015

Study shows how parasitic worm infection increases susceptibility to TB

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

TTUHSC nephrologists to help find new treatment for lupus nephritis

Nephrologists at Texas Tech University Health Science Center El Paso have been invited to participate in a national consortium that's investigating the key causes of lupus nephritis -- an autoimmune disease that can cause kidney failure.

17 Nov 2015

Scientists show how absence of microbiota has remarkable effect against obesity

In the past few years, research on gut microbiota (that is, all microorganisms, mainly bacteria, inhabiting our gut) has started to unravel its tremendous role in our body, and how it symbiotically affects the functioning of our organs. In particular, microbiota has also an impact on the way calories are absorbed and how fat cells develop.

17 Nov 2015

Researchers identify new target for novel immune-oncology treatments

By studying a type of immune cells, a team of researchers at the IRCM led by André Veillette, MD, identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery is published today in the print edition of the scientific journal the Journal of Experimental Medicine.

17 Nov 2015

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

Diabetes prevention begins in the womb

60 million people worldwide are living with diabetes mellitus, and one in ten people over the age of 25 will develop the condition (type 2) at some stage in their lives. Globally, around 3.4 million people die from diabetes and its consequences every year. "Every six seconds, somebody somewhere in the world dies from diabetes", says Alexandra Kautzky-Willer from the Department of Endocrinology and Metabolism at the MedUni Vienna's University Department of Internal Medicine III.

13 Nov 2015

Analyzing potential TB vaccine

When results from a landmark tuberculosis vaccine trial in Cape Town, South Africa were published in The Lancet in February 2013, the headlines were grim, despite hopes that the trial would point toward a successful way to thwart one of the globe's biggest public health threats.

13 Nov 2015

Drug combination produces long-term responses in patients with mantle cell lymphoma

New research from Moffitt Cancer Center and its collaborators find that the drug combination rituximab plus lenalidomide was effective and produced long-term responses in patients with mantle cell lymphoma.

13 Nov 2015

Intake of gluten increases risk of celiac disease in children

Intake of gluten up until two years of age increases risk of celiac disease at least two-fold in children with genetic risk factors for this disease, according a study published in Clinical Gastroenterology and Hepatology the official clinical practice journal of the American Gastroenterological Association.

13 Nov 2015

Some antibiotics may make MRSA more harmful

Treating MRSA with certain first-line antibiotics can actually make MRSA skin infections worse, according to a study published in Cell Host & Microbe.

12 Nov 2015

New research uncovers antibiotic prescription trends across England

New research by Antibiotic Research UK, the world’s first charity created to develop new antibiotics in the fight against superbugs, and high-performance analytic database company EXASOL has discovered that while the number of antibiotic prescriptions is coming down across England, GP practices in the most deprived parts of the country are prescribing 20% more and, worryingly, antibiotic prescriptions are on the increase in these deprived areas.

12 Nov 2015

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Promising new approaches to treating cancer were reported during a recent meeting of researchers from Loyola University Chicago and the University of Notre Dame.

12 Nov 2015

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Learning if a lung cancer patient has genetic mutations can help oncologists determine the best approach to treatment. There are four gene mutations (KRAS, TP53, STK11, and EGFR) that most commonly occur in lung cancer; however, there are limited effective therapies to target these mutations. With this in mind, Moffitt Cancer Center performed an extensive genetic analysis of lung cancer specimens to unravel how mutations in the two of those genes (TP53 and STK11) contribute to the biology of lung cancer and patient outcomes.

12 Nov 2015

Immune System News and Research

Low vitamin D levels may limit effectiveness of HIV treatment

UCLA researchers find new way to reduce ascites with minimal side effects

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

TSRI researchers have new weapons to combat HIV

NSU collaborates with Karolinska Institutet to conduct cell-based biomedical research

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Study shows how parasitic worm infection increases susceptibility to TB

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

TTUHSC nephrologists to help find new treatment for lupus nephritis

Scientists show how absence of microbiota has remarkable effect against obesity

Researchers identify new target for novel immune-oncology treatments

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Diabetes prevention begins in the womb

Analyzing potential TB vaccine

Drug combination produces long-term responses in patients with mantle cell lymphoma

Intake of gluten increases risk of celiac disease in children

Some antibiotics may make MRSA more harmful

New research uncovers antibiotic prescription trends across England

Loyola and Notre Dame researchers report promising new approaches to treating cancer

Moffitt Cancer Center study finds link between common gene mutations and tumor immune surveillance

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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