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Researchers identify cold-sensing protein in mammals

University of Michigan researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

11 Mar 2024

Why covid patients who could most benefit from paxlovid still aren’t getting it

Evangelical minister Eddie Hyatt believes in the healing power of prayer but "also the medical approach." So on a February evening a week before scheduled prostate surgery, he had his sore throat checked out at an emergency room near his home in Grapevine, Texas.

11 Mar 2024

Predicting health futures: Innovative study reveals critical events in disease trajectories

Life-spanning trajectories and critical events that influence hospitalization and death.

11 Mar 2024

Nutrition's crucial role in Alzheimer's progression revealed

Study highlights the strong association between nutrition, particularly malnutrition, and the risk and progression of Alzheimer's disease, emphasizing early dietary interventions as key to reducing AD's global burden.

10 Mar 2024

New research identifies potential drug target to prevent kidney failure

A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a crucial role in limiting the damaging effects of kidney injury that often lead to kidney failure.

9 Mar 2024

Novel genetic link uncovered in generalized pustular psoriasis

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.

9 Mar 2024

mRNA vaccines train T cells in waves, study shows

mRNA vaccines developed against the spike glycoprotein of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2), displayed remarkable efficiency in combating coronavirus 19 (COVID-19).

9 Mar 2024

Scientists transform skin cells into functional eggs in mice

New research from Oregon Health & Science University describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos.

9 Mar 2024

Researchers develop precise drugs to target HIV's Nef protein

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

9 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Study reveals blood markers to predict healthspan and aging trajectories

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age - how fast a person's cells and organs age regardless of their birthdate.

8 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

Zika virus live-attenuated vaccine strains show promise in brain cancer treatment

Scientists from Duke-NUS Medical School (Duke-NUS) have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumor growth, while sparing healthy cells.

8 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Eight voices of progress: AZoNetwork #InspireInclusion for International Women's Day 2024

Each year on March 8th, International Women's Day (IWD) shines a spotlight on the monumental achievements of women around the globe. For 2024, the theme #InspireInclusion invites us to embrace diversity and champion the inclusion of women in all spheres of life.

8 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

More steps a day keep the doctor away

A study in the British Journal of Sports Medicine reveals a clear dose-response relationship between daily step count and reduced risk of mortality and cardiovascular disease, underscoring the importance of walking more, especially for sedentary individuals, with 9,000 to 10,500 steps per day as the optimal range for health benefits.

7 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024