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Chronic interferon exposure drives immunosuppression in tumors

Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most people recognize this progress in breakthroughs like immunotherapy-a treatment strategy first deployed in 2011 that leverages the body's own immune cells to fight cancer and revolutionized the treatment landscape.

10 Sep 2026

Refined starch activates immune pathways after low-carb weight loss

After substantial weight loss on a very-low-carbohydrate diet, participants who switched to a diet rich in refined starch showed greater activation of circulating immune and metabolic pathways than those who continued the low-carbohydrate diet or consumed a high-carbohydrate diet rich in added sugar. Mouse experiments suggested that activation of the complement immune pathway may help explain the inflammatory response associated with starch intake.

10 Sep 2026

Brain interference explains why multitasking becomes difficult

Multitasking feels like a required skill in modern life, but as anyone who has tried keeping track of multiple chat windows, an email inbox, and a stream of phone notifications during a video call can tell you, figuring out which messages are important comes at a cost.

10 Sep 2026

Rituximab alters T-cell metabolism in patients with nephrotic syndrome

Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.

10 Sep 2026

Study reveals structure of color-sensing cone cells in primates

For over 60 years, scientists have debated a basic structural question about cone photoreceptors, the cells that let vertebrates see color: are their light-sensing disk membranes closed off inside the cell, or are they open to the extracellular space? In non-mammalian species, the answer is clear - cone disk membranes typically stay continuous with the surrounding plasma membrane and are therefore open.

10 Sep 2026

Review highlights solute carriers as targets for central nervous system disorders

Solute carriers (SLCs) are specialized transport proteins that control the movement of nutrients, ions and neurotransmitters across cell membranes and are essential for brain metabolism and neuronal communication.

10 Sep 2026

New treatment approach preserves organs, improves survival in head and neck cancer patients

Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.

10 Sep 2026

New funding supports LMU research on pediatric inflammatory bowel disease

The non-profit Boehringer Ingelheim Stiftung supports LMU clinician-scientist Daniel Kotlarz through its Rise up! program.

10 Sep 2026

Evaluating new approaches for rare disease research

Marcel Nelen discusses his team’s early evaluation of a new workflow for rare disease genomics.

From Illumina, Inc. 10 Sep 2026

Spleen imaging features may reveal coronary artery disease risk

A new study led by investigators from Mass General Brigham reveals that certain features in the spleen hidden within imaging scans may signal a person's risk of coronary artery disease (CAD), suggesting targets for prevention and treatment.

9 Sep 2026

Chaotic tumor environments may trigger cancer cell invasion

In 2024, malignant tumors caused more than 21,300 deaths in Austria, 4.7% more than in 2014. Faced with a similarly pressing global challenge, scientists are striving to better understand what drives cancer cells to grow, spread, and invade healthy tissue.

9 Sep 2026

C. diff uses dual-threat sensing system to survive gut stress

The pathogen Clostridioides difficile (C. diff) - a leading cause of hospital-acquired infections - must contend with a variety of threats inside the harsh environment of the gut to survive and grow.

9 Sep 2026

Study reveals processes driving DNA damage in prostate cancer

Cancer begins with errors in the DNA inside our cells, and those errors are often more complicated than a handful of mutated genes.

9 Sep 2026

Early B-cell therapy linked to better MS disease control

For people recently diagnosed with multiple sclerosis (MS), early treatment choices were associated with only slight differences after two years, based on the first treatment they used, according to a study published September 9, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

9 Sep 2026

Technological roadmap proposed for lifetime brain-wide neural recordings

Understanding the brain requires tools that can follow neural activity across many scales: from millisecond electrical spikes in individual neurons to brain-wide circuit dynamics that change over months, years, and even a lifetime.

9 Sep 2026

Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

In mice, intestinal infections reshaped dural CD4+ T-cell populations and seeded the brain’s outer meningeal border with antigen-specific memory cells that persisted for months and mounted rapid recall responses to bloodborne antigens. Oral priming was associated with reduced Salmonella spread to the brain and modest cross-protection in an engineered shared-antigen Candida model, although the researchers could not definitively prove that dural CD4+ T cells alone caused the protection.

9 Sep 2026

New base editing techniques accurately modify genes in human embryos

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

9 Sep 2026

Caloric restriction reduces genetic mutations across the mouse genome

Mutations are changes in the molecular "letters" that make up DNA, the genetic blueprint for cells. Mutations build up with age in every cell when DNA is damaged or when cells make mistakes in fixing or copying it.

9 Sep 2026

Laser-carved microvalves prevent hazardous backflow in medical microcatheters

A single cough, deep breath, or shift in posture can turn life-saving medical microcatheters into hazardous two-way streets.

9 Sep 2026

Single-cell atlas reveals key macrophage subtypes in myocardial infarction

Announcing a new article publication for BIO Integration. Myocardial infarction (MI) is characterized by extensive immune activation and dynamic remodeling of the cardiac microenvironment, in which myeloid cells play critical roles in regulating inflammation and tissue repair.

9 Sep 2026