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CN Bio appoints Dr. Tomasz Kostrzewski as Chief Scientific Officer

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Tomasz Kostrzewski as Chief Scientific Officer.

From CN Bio 30 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

New insights into how dendritic cells arm T cells to fight disease

As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus.

11 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Historically, scientists have studied how cells develop and give rise to specialized cells, such as heart, liver, or skin cells, by examining specific proteins.

8 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Study introduces a new method for efficient delivery of particles into stem cells

A recent study has introduced a new method for delivering particles into stem cells, which are notoriously difficult to penetrate.

8 May 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

Scientists identify a distinct role of retinoic acid during immune response of the gut

A team of scientists from the Renaissance School of Medicine at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

28 Mar 2023

New encoding strategy for single-cell tomograms streamlines data handling and storage

Single-cell analysis is a powerful biomedical technique used in various fields of biology and medicine to identify rare cell populations, track cell development and differentiation, understand disease mechanisms and develop personalized therapies, but it generates large amounts of data that can be difficult to manage.

22 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types - say, heart, liver, blood, and sperm cells - possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

Understanding neural crest cell development will help to better comprehend craniofacial birth defects

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations.

16 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022