Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

New Florida initiative supports healthier lives for cancer survivors statewide

University of West Florida Assistant Professor of Public Health Dr. Karishma Chhabria Unrue has been awarded a nearly $825,000 grant through the Florida Cancer Innovation Fund to lead a statewide initiative focused on improving the health and well-being of breast and prostate cancer survivors.

27 Jun 2026

Recognizing perinatal heart failure early reduces life-threatening risks

Early detection and timely treatment of heart failure in pregnant or postpartum women are crucial to prevent serious complications, such as irregular heartbeat, stroke and death, according to a new American Heart Association scientific statement, "Heart Failure Occurring in the Perinatal Period."

25 Jun 2026

Gene linked to lower BMI points researchers toward a new obesity target

A review in Cardiology in Review highlights GPR75, a receptor for 20-HETE, as a promising therapeutic target for obesity and metabolic syndrome. Evidence from genetic studies, cell experiments, and mouse models suggests that blocking this pathway could influence weight gain, insulin resistance, hypertension, inflammation, and vascular dysfunction.

25 Jun 2026

Plant-based Mediterranean-style diet cuts heart disease risk by 26%

A 20-year study links plant-based Mediterranean diets to lower heart disease risk, highlighting the importance of sustainable eating for cardiovascular health.

24 Jun 2026

Sugar-coated nanoparticles extend survival in aggressive glioblastoma mouse model

Researchers at Oregon State University have potentially found a new way to treat the most aggressive form of brain cancer, glioblastoma, whose two-year survival rate is less than 30%.

23 Jun 2026

AI image-based risk scores enable dynamic breast cancer assessment

Using artificial intelligence (AI), researchers found that image-based risk scores for breast cancer derived from screening mammograms evolve over time and differ between women who develop cancer and those who do not, opening the door to a new era of dynamic breast cancer risk assessment.

23 Jun 2026

Elite athletes with higher vitamin D show healthier lipid profiles

Higher serum 25-hydroxyvitamin D levels were independently associated with lower LDL-C, triglycerides, and lipoprotein(a) in 773 male professional athletes. The cross-sectional study cannot establish causality, but it suggests that vitamin D status may be linked to cardiovascular risk-related lipid markers, even in elite athletic populations.

23 Jun 2026

Statins may trigger muscle side effects by activating inflammatory danger signals

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, reduced protein synthesis, and weakened muscle function.

22 Jun 2026

Mount Sinai study connects social determinants of health to disease risks

A new study from the Icahn School of Medicine at Mount Sinai shows that social determinants of health-including environmental conditions, health behaviors, access to resources, and social well-being-can play an equally important or even greater role than genetics in predicting a person's risk of developing common diseases.

22 Jun 2026

Poll reveals gaps in brain health awareness among older adults

Nearly all Michiganders age 50 and over say it's very important to keep their brains healthy as they grow older, a new poll finds.

18 Jun 2026

Epigenetic drugs improve blood vessel health in obesity and diabetes

People with obesity and type 2 diabetes are at high risk of blood vessel damage. This risk depends not only on the genes a person carries, but also on how they are "read".

18 Jun 2026

Microplastics worsen liver damage under high-fat dietary conditions

Microplastics – minuscule pieces of plastic broken down from larger plastic waste – are a growing concern for human health, especially for the liver.

17 Jun 2026

Resistance training reduces major heart disease risk for active women

Women who lift weights may have a lower risk of major heart disease, especially when combined with aerobic exercise, according to a new study published today in JACC, the flagship journal of the American College of Cardiology.

17 Jun 2026

Semaglutide, omega-3s and diet shift epigenetic aging clocks in human studies

A systematic review identified 41 human studies evaluating interventions targeting next-generation DNA methylation-based aging clocks. Pharmaceutical, lifestyle, supplement, clinical, and psychosocial interventions shifted some clock outputs, but these biomarkers remain investigational rather than proven clinical surrogates.

16 Jun 2026

Study identifies top predictors for weight loss using tirzepatide

One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

16 Jun 2026

GLP-1s may improve testosterone levels and sperm quality in men with obesity

GLP‑1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2026

Researchers map rare DHDDS disease mechanism using lab-grown mini brains

Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early childhood. This Parkinson's-like condition is extremely rare, and until recently, parents were told that there was nothing that could be done to slow down its progression.

15 Jun 2026