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Etomidate proves safer than ketamine for emergency intubations

Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published Dec. 9 in the New England Journal of Medicine.

12 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Fear strongly influences pain perception in inflammatory bowel disease patients

Pain perception in affected individuals is more strongly influenced by learned fear than in healthy individuals. Changes along the gut-brain axis related to chronic inflammation may explain this.

12 Dec 2025

Landmark RSI trial reshapes sedative selection for emergency airway management

9 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

First new fibromyalgia drug in 15 years, Tonmya (cyclobenzaprine HCl) gains FDA approval and hits pharmacy shelves

In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel sublingual therapy Tonmya has received approval from the U.S. Food and Drug Administration (FDA) - marking the first new drug for Fibromyalgia in more than 15 years.

From Hanson Wade Group - Non-Opioid Pain Therapeutics Summit 5 Dec 2025

Medical cannabis evidence falls short for most conditions

Medical cannabis lacks adequate scientific backing for most of the conditions it is commonly used to treat, including chronic pain, anxiety and insomnia, according to a comprehensive review led by UCLA Health.

3 Dec 2025

How anger and injustice shape the course of chronic pain

We all know stress can worsen pain, but new research shows that anger and a sense of injustice may be even more powerful triggers. In a study of more than 700 people living with chronic pain, researchers uncovered four distinct "anger profiles" that help explain why some patients hurt more, and longer, than others.

3 Dec 2025

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

Chronic muscle tension is a common underlying factor in many pain disorders, causing reduced arterial blood flow, tissue hypoxia, and the release of inflammatory mediators.

28 Nov 2025

Genetic factors behind impulsive choices tied to metabolic and mental health

Researchers from University of California San Diego have identified 11 genetic regions linked to delay discounting - the tendency to prefer smaller, immediate rewards over larger, delayed ones - shedding new light on how impulsive decision-making relates to both mental and physical health.

24 Nov 2025

Can diet calm early memory problems? Anti-inflammatory Mediterranean eating shows promise

Older women who follow a strongly anti-inflammatory Mediterranean diet report far fewer subjective memory complaints than those who do not. The AnMED pattern outperforms both traditional Mediterranean and MIND diets, showing a clear advantage for protecting early cognitive symptoms.

24 Nov 2025

Most Medicaid patients do not receive life-saving drugs for opioid use disorder

A US study of more than a million Medicaid enrollees, newly diagnosed with opioid use disorder (OUD), finds most – nearly seven in 10 – are not receiving access to potentially life-saving drugs within six months.

24 Nov 2025

Does coffee truly boost memory and focus or is it all hype?

Coffee’s bioactive compounds, especially caffeine, show potential cognitive, neuroprotective, and neuroplasticity benefits across animal and human studies. However, most findings are observational, mechanisms remain uncertain, and optimal intake is still unclear.

23 Nov 2025

Masturbation could improve mood and sleep during menopause

This study found that about one in five perimenopausal and postmenopausal women experienced measurable symptom relief from masturbation, particularly for sleep and mood. Nearly half said they would consider using it for symptom relief if their doctor recommended it, although many had never discussed it with a clinician.

23 Nov 2025

Chronic pain in adults linked to increased risk of developing high blood pressure

Chronic pain in adults may increase their risk of high blood pressure, and the location and extent of pain and if they also had depression were contributing factors, according to new research published today in Hypertension, an American Heart Association journal.

17 Nov 2025

Digital biomarkers revolutionize early diagnosis of endometriosis and pelvic conditions

For years, conversations around hormonal and pelvic health have been overshadowed by stigma, silence, and misunderstanding. Millions of women have endured pain without answers, suffering in silence. But change is coming

7 Nov 2025

Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system.

7 Nov 2025

Intensive mind-body retreat rapidly alters brain function and blood biology

Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques, including meditation and healing practices, produced rapid and wide-ranging changes in brain function and blood biology.

6 Nov 2025

Researchers develop new checklist to prevent fraud in online clinical trials

The rise in virtual research since the COVID-19 pandemic has created opportunities for researchers to expand and diversify clinical trials, but it has also opened up avenues for fraudulent participation in these studies.

6 Nov 2025