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Major trial seeks to test semaglutide on adults with alcohol and opioid use disorder

The Center for Addiction Science, Policy and Research (CASPR) and the Allegheny County Department of Human Services are preparing to launch a major $13.3 million randomized controlled trial to test whether weekly semaglutide, as an additional support to existing care, can reduce alcohol and opioid use and reduce criminal-justice involvement while improving employment, health, and housing outcomes among people at elevated risk of criminal-justice involvement.

13 Oct 2026

FDA approves new Parkinson’s drug pioneered by UVA scientists

The federal Food and Drug Administration has approved a new Parkinson's disease drug that was based on research by UVA Health scientists.

13 Oct 2026

Medical cannabis benefits for insomnia remain uncertain, Cochrane review finds

A new Cochrane review finds that existing evidence is too uncertain to determine whether medical cannabis improves sleep or daytime functioning in people with insomnia.

12 Oct 2026

Long-term anabolic steroid use linked to lasting heart damage

Long-term use of anabolic-androgenic steroids (AAS) has serious consequences for the heart, according to a new study that has been following weightlifters for nearly 10 years.

12 Oct 2026

Review highlights EP4 receptor as target for inflammatory diseases

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases.

12 Oct 2026

Buck Institute and Georgetown lead effort mapping harmful protein changes before disease begins

A research "super team" co-led by theBuck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments.

12 Oct 2026

Magnetically guided millirobots deliver targeted drugs to beating hearts

Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

12 Oct 2026

Systemic failures protect medical professionals who commit serious crimes

Institutional fear of litigation, reputation damage and career consequences can create a protective shield around the small minority of doctors who commit serious crimes against patients, experts warn.

12 Oct 2026

Intensive breathwork reduces brain blood flow and alters neural communication

Intensive breathing exercises can reduce blood flow to the brain by up to 45% and alter communication between brain networks, according to a new brain-imaging study.

11 Oct 2026

Stopping GLP-1 drugs often brings weight back. A small trial suggests ways to slow it

In a randomized pilot trial of 39 adults, researchers found that participants receiving medically tailored meals or Noom regained about 3.6% of their body weight over four months after stopping GLP-1 therapy, compared with about 11% under usual care. These exploratory findings suggest structured support may slow early weight regain, but the small sample and short follow-up leave lasting benefits uncertain.

11 Oct 2026

Cyberbullying acts as an extension of in-person school violence

A new study of 4,200 adolescents revealed that cyberbullying rarely occurs in isolation; it almost always functions as an extension of physical and verbal aggression already present in the school environment.

9 Oct 2026

Marketing tactics used by pharma companies influence physician prescribing habits

A new Cochrane review led by a team of international researchers including from U of T, has found that marketing strategies used by pharmaceutical companies such as payments for consulting and advisory board membership and free meals offered to physicians, can negatively influence prescribing habits.

9 Oct 2026

Oncopeptides confirms blood-brain-barrier penetration based on data from first patients in glioblastoma Window-of-Opportunity (WoO) study

Oncopeptides AB (publ), a biotech company specializing in difficult-to-treat cancers, today announces data from the first patients in its ongoing clinical Window-of-Opportunity (WoO) study, OP-701 (INSULA), evaluating its proprietary Peptide Drug Conjugate (PDC) platform in glioblastoma.

9 Oct 2026

$13.1 million grant backs bacterial therapies for resistant breast cancer

A scientist at Weill Cornell Medicine is working with colleagues at the University of Massachusetts Amherst on new, complementary research efforts engineering therapeutic Salmonella to target critical gaps in treatment for drug-resistant triple-negative breast cancers.

9 Oct 2026

Rare dendritic cells may promote immune tolerance in metastatic cancer

This study was co-led by Steven Blum, MD. Gary Reynolds, MD, PhD, Samuel Klempner, MD, and Alexandra-Chloé Villani, PhD, jointly supervised the work at the Krantz Family Center for Cancer Research within the Mass General Brigham Cancer Institute and the Mass General Brigham Center for Immunology & Inflammatory Diseases (CIID).

8 Oct 2026

New long-acting HIV treatment offers hope for drug-resistant infections

A new long-acting HIV treatment could expand options for people who have trouble taking daily pills and whose virus is resistant to some commonly used HIV drugs, according to a new UC San Francisco study.

8 Oct 2026

Disrupted circadian rhythms may influence tumor immunity and cancer spread

Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal cancer.

8 Oct 2026

A New Approach to Preventing Bladder Cancer Recurrence

Innovative techniques using electrical energy to treat bladder cancer may lower recurrence rates and minimize the need for radical surgical interventions.

8 Oct 2026

New modeling reveals high societal value of early Alzheimer's care

New treatments that can slow the progression of Alzheimer's disease could provide significant lifetime benefits to patients and society, with even greater benefits when initiated earlier, according to new research from the USC Schaeffer Center for Health Policy & Economics.

7 Oct 2026

Long-term opioid use does not improve chronic back pain outcomes

Taking opioids for years does not seem to improve pain and functioning in people with chronic back pain, according to a new Northwestern University study that compared 70 long-term opioid users to 70 similar patients not taking opioids.

6 Oct 2026