Genomic Sequencing News and Research

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The hidden factors of resistance: how pathogen diversity drives antibiotic response

Researchers aimed to understand the role of within-host microbial diversity on antimicrobial resistance.

14 Jul 2023

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

11 Jul 2023

Researchers identify Paenibacillus bacteria as responsible for postinfectious hydrocephalus in Uganda

In 2007, Yale pediatric neurosurgeon Steven Schiff, MD, visited his friend, Benjamin Warf, MD, at the CURE Children's Hospital of Uganda.

20 Jun 2023

From COVID-19 to future threats: building a global genomic surveillance network

Researchers present a modular framework for global sustainable networks of viral genomic surveillance.

16 Jun 2023

Newborn genome sequencing project identifies unanticipated disease risks

Genomic sequencing of newborns reveals unanticipated genetic risks, prompting actionable medical interventions and potential life-saving care for infants and their families. This study highlights the value of comprehensive sequencing in newborns for early detection and management of genetic conditions.

7 Jun 2023

Large-scale comprehensive sequencing helps downstream medical care in newborns

Researchers who lead the world's first comprehensive sequencing program for newborn infants have published the next chapter in the ongoing study of the BabySeq Project, with new findings on infants and families who have been followed for 3-5 years.

6 Jun 2023

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Researchers from Children's Hospital of Philadelphia (CHOP) recently discovered that extremely thorough "deep sequencing" of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods.

1 Jun 2023

WHO chief: World must prepare for deadlier outbreak than COVID-19

The world should be prepared to respond to a disease outbreak of "even deadlier potential" than COVID-19, the head of the WHO said after the UN agency launched a global network to monitor disease threats.

23 May 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

The African Personalized Medicine Agenda

In this interview, Rizwana Mia, the Senior Program Manager at South African Medical Research Council, talks to News Medical about the African personalized medicine agenda.

From MGI 4 May 2023

Wildlife in Britain found free of SARS-CoV-2, but novel virus discovered in stoats

Scientists in the United Kingdom have conducted a large-scale screening for sarbecoviruses and pan-coronaviruses in British Wildlife to investigate the occurrence of widespread spillover events. They have identified a novel minacovirus in stoats recently introduced to the Orkney Islands.

3 May 2023

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Researchers discuss major healthcare-associated pathogens, as well as current and future public health priorities related to these microorganisms.

2 May 2023

Tracking SARS-CoV-2 Omicron variant XBB1.16

The World Health Organization recently named the SARS-CoV-2 Omicron variant XBB1.16 a variant of interest to encourage tracking of this genetic variant of the pandemic coronavirus.

28 Apr 2023

Heterogeneity of autism makes clinical trials difficult, says CHLA expert

Each year in the U.S. the incidence of autism spectrum disorder increases, yet the number of medications to treat the core features of autism remains stuck at zero.

28 Apr 2023

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Researchers explored the possible transmission of SARS-CoV-2 to zoo employees from an African lion.

19 Apr 2023

Understanding human mycobiome commensalism and pathogenesis

Researchers explored commensalism and pathogenesis relationships in the human mycobiome.

18 Apr 2023

New AI tool accurately predicts aggressiveness of colorectal cancer

A new artificial intelligence model designed by researchers at Harvard Medical School and National Cheng Kung University in Taiwan could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer, the second deadliest cancer worldwide.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view.

27 Mar 2023