GlaxoSmithKline News and Research

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R21/Matrix-M booster maintains high efficacy against first and multiple episodes of clinical malaria

The phase 1/2b clinical trial on R21/Matrix-M malaria vaccine has recently reported the safety and efficacy of booster vaccination at 12 months.

15 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Novel tests detect common cancer signals across over 50 types of cancer

Cancer doctors, care providers and payers need to get ready for a major shift in early cancer detection that will affect almost every stage of cancer diagnosis and treatment. New data supporting the accuracy of multi-cancer early detection (MCED) blood testing (1), presented at the ESMO Congress 2022, have major implications for future cancer care provision, said Fabrice André, ESMO 2022 Scientific Co-Chair.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Newly discovered protein could help to improve fertility treatments

Scientists have discovered a new protein which helps sperm fuse to an egg and is fundamental for human fertilization.

8 Sep 2022

Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

8 Sep 2022

Study: Number of babies born with cytomegalovirus decreased during the COVID-19 pandemic

Published in JAMA, University of Minnesota Medical School researchers discovered the number of babies born in Minnesota with cytomegalovirus (CMV) decreased significantly during the COVID-19 pandemic.

6 Sep 2022

Scientists begin phase 2 clinical trials of lupus pill

Lupus is an autoimmune disease that attacks organs and can be fatal. There's no cure, so current treatments aim to limit damage and ameliorate symptoms.

22 Aug 2022

E-cigarette use may help people decrease their dependence on combustible cigarettes

Electronic cigarettes have attracted media and consumer attention for claims of their addictive nature, variety of flavors and increased use among teens, sparking regulatory oversight and policies.

15 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

What does the future look like for TB care?

In this interview, we speak to Charles Wells from Gates MRI about their current research into tuberculosis (TB) as well as the recent updated guidelines for TB care.

5 Aug 2022

Booster dose of SARS-CoV-2 vaccine benefits lupus patients

People with systemic lupus erythematosus, or SLE, who received a "booster" dose of SARS-CoV-2 vaccine after full vaccination are roughly half as likely to have a subsequent "breakthrough" COVID-19 infection, a new study shows.

13 Jul 2022

New discovery could lead to more effective treatments for asthma sufferers

New research led by Edith Cowan University has made an important discovery that could lead to more effective treatments for the world's 262 million asthma sufferers.

4 Jul 2022

Androgen receptor signaling affects response to targeted therapy in people with melanoma

Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers from The University of Texas MD Anderson Cancer Center showed in a study published today in Nature.

15 Jun 2022

Prenatal exposure to antiseizure drugs associated with risk of autism and intellectual disability

Women with epilepsy often need medication to prevent seizures during pregnancy. Previous studies have found an association between exposure to the antiseizure medication valproate during pregnancy and risk of autism and low IQ in the offspring.

2 Jun 2022

World's first malaria vaccine may be available soon across Sub-Saharan Africa

The world's first malaria vaccine will soon be available across Sub-Saharan Africa, according to PATH, partners of the vaccine developers, as positive results from the pioneering jab pile up.

5 May 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

Dentures may negatively impact a person's overall nutrition, research suggests

Dentures may have a potentially negative impact on a person's overall nutrition, according to new research from Regenstrief Institute and Indiana University School of Dentistry.

21 Apr 2022

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria.

7 Apr 2022

Why Black and Hispanic seniors are left with a less powerful flu vaccine

At Whitman-Walker Health, Dr. David Fessler and his staff administer high-dose influenza vaccine to all HIV-positive and senior patients.

6 Apr 2022

GlaxoSmithKline News and Research

R21/Matrix-M booster maintains high efficacy against first and multiple episodes of clinical malaria

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Novel tests detect common cancer signals across over 50 types of cancer

Pollutant particles in the air trigger lung cancer in non-smokers

Newly discovered protein could help to improve fertility treatments

Triplet therapy slows progression of advanced kidney cancer

Study: Number of babies born with cytomegalovirus decreased during the COVID-19 pandemic

Scientists begin phase 2 clinical trials of lupus pill

E-cigarette use may help people decrease their dependence on combustible cigarettes

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

What does the future look like for TB care?

Booster dose of SARS-CoV-2 vaccine benefits lupus patients

New discovery could lead to more effective treatments for asthma sufferers

Androgen receptor signaling affects response to targeted therapy in people with melanoma

Prenatal exposure to antiseizure drugs associated with risk of autism and intellectual disability

World's first malaria vaccine may be available soon across Sub-Saharan Africa

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

Dentures may negatively impact a person's overall nutrition, research suggests

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

Why Black and Hispanic seniors are left with a less powerful flu vaccine

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