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Comprehensive research identifies most effective ADHD treatments

The most comprehensive review to date of ADHD treatments has found that medication for children and adults, and cognitive behavioral therapy for adults, remain the most effective approaches, backed by the strongest short-term trial evidence.

26 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Scientists reverse aging in blood stem cells by restoring lysosome function

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

24 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

Alzheimer’s drugs improve key cognitive skills in children with autism and low IQ

The review synthesizes evidence on whether Alzheimer’s disease medications can improve neurocognitive outcomes in children and adolescents with autism and low IQ. Across 12 studies, preliminary findings show promising gains in language, executive function, learning and memory, and general cognitive ability, particularly in younger children.

18 Nov 2025

Maternal obesity raises childhood epilepsy and disability risks, new study shows

Higher maternal BMI before pregnancy is linked to increased risks of epilepsy and intellectual disability in young children, even after extensive adjustment for maternal and neonatal factors. Associations with autism spectrum disorder and ADHD disappear after full adjustment, highlighting the potential mediating role of perinatal complications.

17 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

ADHD symptoms linked to earlier substance use in young sexual minority men

Young sexual minority men – a term used to describe gay, bisexual, and other men who have sex with men – with attention-deficit/hyperactivity disorder (ADHD) symptoms are more likely to begin using substances such as cigarettes, alcohol, cannabis, stimulants and illicit drugs at an earlier age, according to Rutgers Health researchers.

13 Nov 2025

Study: Biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries

A new study published in Molecular Psychiatry reveals that the biological underpinnings of autism and ADHD may transcend traditional diagnostic boundaries.

12 Nov 2025

No, taking paracetamol while pregnant doesn’t cause autism or ADHD, major review finds

Researchers reviewed nine systematic reviews on paracetamol use during pregnancy and found that while some studies suggested links to ADHD or autism, the evidence was of low quality and confounded by shared familial factors. Sibling-controlled analyses showed no causal relationship between prenatal paracetamol exposure and neurodevelopmental disorders in children.

11 Nov 2025

Maternal paracetamol use during pregnancy not linked to autism or ADHD in children

Existing evidence does not clearly link paracetamol (acetaminophen) use during pregnancy with autism or ADHD in children, finds an in-depth evidence review published by The BMJ today, in direct response to recent announcements around the safety of using paracetamol in pregnancy.

10 Nov 2025

Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little is actually known about the impact that CBD has on the nervous system.

7 Nov 2025

While politicos dispense blame, these doctors aim to take shame out of medicine

The distress that Will Bynum later recognized as shame settled over him nearly immediately.

5 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder

In a peer-reviewed article published today in Brain Medicine, a European research team presents a focused review of emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder (OCD).

28 Oct 2025

New computer model lets researchers simulate how brain circuits make decisions

Every day, your brain makes thousands of decisions under uncertainty. Most of the time, you guess right. When you don't, you learn. But when the brain's ability to judge context or assign meaning falters, thoughts and behavior can go astray.

22 Oct 2025

Study links child behavior stress and lower self-regulation in parents

Any parent will tell you that raising a child isn't easy. While the experience can be filled with joy and love and fulfilment, emotional, financial and marital stress will present challenges to any family.