Immunoassay News and Research

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Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

Techniques used for SARS-CoV-2 detection in body fluids

In a recent review published in the journal Trends in Analytical Chemistry, researchers provided a comprehensive overview of the current techniques used for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in bodily fluids.

7 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences 5 Sep 2022

SARS-CoV-2 nucleocapsid antigen levels and patient outcomes

In a new study, researchers assessed the correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) antigen levels and hospitalized patient outcomes.

31 Aug 2022

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Spear Bio, Inc.announced that the Institute's DNA nanotechnology-driven ultrasensitive SPEAR protein-detection technology has been licensed to the newly formed Boston-based startup.

23 Aug 2022

Human antibody responses to SARS-CoV-2 infection after two years

Scientists describe a protocol to evaluate antibody response dynamics up to two years following SARS-CoV-2 infection.

21 Aug 2022

Study warns of a potential Sindbis virus epidemic in 2022

Researchers seek to raise awareness of a potentially impending Sindbis virus epidemic.

11 Aug 2022

Nanoparticle-based lateral flow immunoassay for the detection of anti-SARS-CoV-2 neutralizing antibodies

In a recent Biomaterials study, researchers developed AIEgen-embedded polystyrene (PS) nanoparticles-based LFIA that can accurately detect anti-SARS-CoV-2 NAb in serum samples of vaccinated individuals.

11 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Accurate rapid-testing device displays antibody levels in an easily readable way

Vaccines have become the most important weapon in the fight against the COVID-19 pandemic, but antibody levels after vaccination decay quickly over time.

28 Jul 2022

The kinetics of SARS-CoV-2 nucleocapsid antibodies up to 21 months after infection

Researchers found significant seroreversion of total anti-nucleocapsid immunoglobulin.

28 Jul 2022

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

In a new study, researchers reported that Pfizer’s BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 does not affect the honeymoon phase of type 1 diabetes (T1D).

13 Jul 2022

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

Researchers compared the immunogenicity and safety of the protein-based heterodimer vaccine (PHH-1V) and BNT162b2 COVID-19 vaccines.

8 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Despite significant and stunning advances in vaccine technology, the COVID-19 global pandemic is not over. A key challenge in limiting the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is identifying infected individuals.

1 Jul 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

A cancer patient who had SARS-CoV-2 for over eight months

In a recent study posted to the medRxiv* pre-print server, researchers in Israel described the case of a severely immunocompromised cancer patient who developed a chronic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

28 Jun 2022

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

Researchers presented the PREVENT-19 phase 3 trial findings on the effectiveness of the NVX-CoV2373 adjuvanted, recombinant S nanoparticle vaccine.

27 Jun 2022

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

Natural serological evidence of SARS-CoV-2 infection in lactating cows

Researchers observed SARS-CoV-2 seroconversion in lactating cows.

7 Jun 2022