Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.

29 Jul 2022

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized how molecules came together to spark this transition.

28 Jul 2022

New method for organoid production could help advance research studies

As the idea of growing tiny human organs in lab dishes has moved in recent years from futuristic science fiction to actual bioscientific reality, the usefulness of organoids as a research tool for studying the digestive system swiftly encountered a bottleneck - these valuable tissues are quite difficult to make.

28 Jul 2022

Novel targeted therapy may be an effective treatment option for neuroblastoma

New research from VCU Massey Cancer Center - published Thursday in Cell Reports - demonstrated that a novel targeted therapy could be an effective treatment option for a deadly pediatric cancer known as neuroblastoma.

28 Jul 2022

A pair of analyses reveals early epicenter of the COVID-19 pandemic

The COVID-19-causing coronavirus, SARS-CoV-2, likely first spread to humans from animals in two separate transmission events in a Wuhan market in late November 2019, according to a pair of analyses by international teams co-led by Scripps Research scientists.

26 Jul 2022

Stopping 'budding' viruses in their tracks

Paramyxoviruses have the potential to trigger a devastating pandemic. This family of viruses includes measles, Nipah virus, mumps, Newcastle disease and canine distemper.

20 Jul 2022

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

State-of-the-art laboratories significantly expand project capacity to meet increasing market demand for Organ-on-a-Chip research services.

From CN Bio 19 Jul 2022

Scientists develop an improved pharmaceutical drug for the treatment of atrial fibrillation

Scientists from the National University of Singapore Department of Pharmacy have developed an improved pharmaceutical drug for the treatment of the most common heart rhythm disturbance – atrial fibrillation (AF).

18 Jul 2022

Texas Biomed professor to join $577 million effort for developing antivirals against COVID-19 and other viruses

As the coronavirus waves keep coming and cases are on the rise once again, the National Institutes of Health (NIH) recently launched a $577 million effort to develop antivirals against COVID-19 and other viruses with high pandemic potential.

15 Jul 2022

The Mark Foundation for Cancer Research announces latest ASPIRE awards for eight outstanding projects

The Mark Foundation for Cancer Research announced eight outstanding research projects to receive its latest class of ASPIRE awards.

14 Jul 2022

Novel technique could offer an improved route to drug discovery and development

A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.

14 Jul 2022

Hitting rewind on the spread of pancreatic cancer

News-Medical speaks to Linxiang Lan, a staff scientist at The Institute of Cancer Research, about a fundamental discovery that could pave way for new pancreatic cancer treatments.

14 Jul 2022

Diversifying STEM; the Importance of Representation, Equity, and Inclusion

As part of our SLAS Europe 2022 coverage, we speak to Paula Petrone, Associate Research Professor at ISGlobal, about the importance of representation, inclusion, and equity in the STEM fields.

From Society for Laboratory Automation and Screening (SLAS) 13 Jul 2022

Scientists uncover how the innate immune system detects and fights HIV-1

Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system.

8 Jul 2022

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Researchers assessed the different mutations of concern in the SARS-CoV-2 receptor-binding domain.

6 Jul 2022

BICO; Combining Life Sciences Solutions to Further Human Health

As part of our SLAS Europe 2022 coverage, we speak to Héctor Martínez, CTO of BICO, about the technology and services they offer within life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 5 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

The Wake Forest Institute for Regenerative Medicine researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells.

28 Jun 2022

Sanford Burnham Prebys scientist receives NIH grant to continue research on cellular signaling in cancer

Brooke Emerling from Sanford Burnham Prebys has been awarded a new grant from the National Institutes of Health to continue her work on cellular signaling in cancer.

27 Jun 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Drug Discovery News and Research

Further Reading

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

New method for organoid production could help advance research studies

Novel targeted therapy may be an effective treatment option for neuroblastoma

A pair of analyses reveals early epicenter of the COVID-19 pandemic

Stopping 'budding' viruses in their tracks

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

Scientists develop an improved pharmaceutical drug for the treatment of atrial fibrillation

Texas Biomed professor to join $577 million effort for developing antivirals against COVID-19 and other viruses

The Mark Foundation for Cancer Research announces latest ASPIRE awards for eight outstanding projects

Novel technique could offer an improved route to drug discovery and development

Hitting rewind on the spread of pancreatic cancer

Diversifying STEM; the Importance of Representation, Equity, and Inclusion

Scientists uncover how the innate immune system detects and fights HIV-1

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

BICO; Combining Life Sciences Solutions to Further Human Health

Combining AI and Zebrafish to Accelerate Drug Discovery

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

Sanford Burnham Prebys scientist receives NIH grant to continue research on cellular signaling in cancer

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Event guide: The 5th ALS Drug Development Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Expanding access to NMR with the Fourier 80 Duo