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Blood test provides tool essential to trials of therapies for Huntington's disease

An assay designed to measure normal and abnormal forms of the huntingtin protein - the mutated form of which causes Huntington's disease - was successful in detecting levels of the mutant protein in a large multicenter study of individuals at risk for the devastating neurological disorder.

30 Aug 2013

Results from Phase II START study published in The Lancet Diabetes & Endocrinology

Results from the START clinical study (Study of Thymoglobulin to Arrest Newly Diagnosed Type 1 Diabetes), led by Dr. Steve Gitelman (University of California, San Francisco) and sponsored by the Immune Tolerance Network, are published today in The Lancet Diabetes & Endocrinology.

28 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

New radiation treatment can reduce bone pain, extend lives of prostate cancer patients

Prostate cancer that has spread to the bones can cause pain and fractures. Loyola University Medical Center is among the first hospitals in Chicago to offer a new targeted radiation treatment that can reduce bone pain and the incidence of fractures - and also extend patients' lives.

23 Aug 2013

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

Takeda Pharmaceutical Company Limited today announced that results from two Phase 3 studies evaluating vedolizumab, an investigational humanized monoclonal antibody, for the treatment of adults with moderately to severely active ulcerative colitis and Crohn’s disease, were published in the August 22, 2013 issue of the New England Journal of Medicine.

22 Aug 2013

Research suggests restricting calories may improve success of cancer treatment

New research suggests that restricting calories for a defined period of time may improve the success of cancer treatment, offering valuable new data on how caloric intake may play a role in programmed cancer cell death and efficacy of targeted cancer therapies. Study results were published online today in Blood, the Journal of the American Society of Hematology (ASH).

22 Aug 2013

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

mmunetics, Inc., a leading clinical test provider, has received U.S. Food and Drug Administration (FDA) clearance for its BacTx® rapid test for bacteria in apheresis platelets. The BacTx system is a colorimetric assay that can detect aerobic, anaerobic, gram-negative and gram-positive bacteria in a single test.

20 Aug 2013

Illumina announces availability of its newest reagent kits for MiSeq benchtop sequencer

Illumina, Inc. today announced the availability of its newest reagent kits for the MiSeq, the industry's most accurate and easiest-to-use benchtop sequencer. The improved chemistry doubles sequencing output to 15 gigabases (Gb) by increasing the number of sequencing reads (up to 25 million reads) and overall read length (up to 2x300 base pairs). These innovations enable researchers to perform new applications including exome sequencing on the MiSeq.

From Illumina, Inc. 19 Aug 2013

Study: Gene that controls ageing process linked to cancer

A gene that helps control the ageing process by acting as a cell's internal clock has been linked to cancer by a major new study.

19 Aug 2013

Study reports high survival rates for children with rare subtype of leukaemia

A pioneering genetic study means that children with a rare subtype of leukaemia have 75% less chance of their leukaemia recurring.

13 Aug 2013

Study identifies individuals who benefit from vitamin D supplementation

Studying the expression of genes that are dependent on vitamin D makes it possible to identify individuals who will benefit from vitamin D supplementation, shows a University of Eastern Finland study published recently in PLoS One.

13 Aug 2013

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes.

12 Aug 2013

New microfluidic chip can capture live CTCs from patient's blood

Tumor cells circulating within a patient's bloodstream can carry cancer from a primary tumor site to distant sites of the body, spreading the disease.

9 Aug 2013

Eisai's investigational compound receives orphan drug designation for cutaneous t-cell lymphoma

Eisai Inc. announced today that the U.S. Food and Drug Administration has granted orphan drug designation to its investigational compound (E7777) for cutaneous t-cell lymphoma. E7777 is designed to have an improved purity profile and manufacturing process.

9 Aug 2013

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

PerFix-Expose1 and PerFix-nc1, innovative new reagent kits for intracellular staining from Beckman Coulter Life Sciences, minimize sample manipulation for a streamlined workflow that delivers high quality results. Developed for use on Beckman Coulter’s Gallios1 and Navios2 series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes, the kits enable a clear focus on the cytoplasmic and nuclear compartments of the cell.

8 Aug 2013

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Roche announced today the global launch of a new software update that significantly extends the range of amplicon lengths available for targeted next-generation sequencing studies on the 454 GS FLX+ System.

7 Aug 2013

Immune function restored in spinal injured mice

In a new study, researchers at The Center for Brain and Spinal Cord Repair at The Ohio State University Wexner Medical Center show that is possible to restore immune function in spinal injured mice.

7 Aug 2013

Community-based pharmacies can be effective locations for offering rapid HIV testing, find researchers

Researchers at Albert Einstein College of Medicine of Yeshiva University have found that community-based pharmacies can be effective locations for offering rapid HIV testing, diagnosing HIV, and connecting those who test positive with medical care quickly. The study is in the August issue of the journal AIDS Patient Care and STDs.

7 Aug 2013

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Patients with celiac disease who had persistent intestine damage (identified with repeat biopsy) had a higher risk of lymphoma than patients whose intestines healed, according to findings published in the August 6, 2013, issue of Annals of Internal Medicine.

6 Aug 2013

Researchers reveal process by which pancreatic inflammation morphs into pancreatic cancer

Researchers at Mayo Clinic in Florida have revealed the process by which chronic inflammation of the pancreas, pancreatitis, morphs into pancreatic cancer. They say their findings point to ways to identify pancreatitis patients at risk of pancreatic cancer and to potential drug therapies that might reverse the process.

6 Aug 2013

Leukocyte News and Research

Blood test provides tool essential to trials of therapies for Huntington's disease

Results from Phase II START study published in The Lancet Diabetes & Endocrinology

Study shows ABL kinases have enhanced expression and activity in CML

New radiation treatment can reduce bone pain, extend lives of prostate cancer patients

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

Research suggests restricting calories may improve success of cancer treatment

Immunetics receives FDA clearance for BacTx rapid test for bacteria in apheresis platelets

Illumina announces availability of its newest reagent kits for MiSeq benchtop sequencer

Study: Gene that controls ageing process linked to cancer

Study reports high survival rates for children with rare subtype of leukaemia

Study identifies individuals who benefit from vitamin D supplementation

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

New microfluidic chip can capture live CTCs from patient's blood

Eisai's investigational compound receives orphan drug designation for cutaneous t-cell lymphoma

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Immune function restored in spinal injured mice

Community-based pharmacies can be effective locations for offering rapid HIV testing, find researchers

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Researchers reveal process by which pancreatic inflammation morphs into pancreatic cancer

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