Next generation sequencing NGS News and Research

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EdgeBio introduces Science as a Service concept built on top of CLC Genomics Server

Today at the inaugural Beyond Sequencing conference in San Francisco, EdgeBio introduced their Science as a Service concept built on top of CLC bio's enterprise platform, CLC Genomics Server. EdgeBio's end-to-end service concept leads each scientist and project from conception and project design through bioinformatics and analysis.

23 Jun 2010

AMP raises ethical, laboratory practice concerns in whole genome sequencing at SACHGS meeting

Today, the Association for Molecular Pathology (AMP) presented public comments to the Secretary's Advisory Committee on Genetics, Health and Society (SACHGS) meeting focused on whole genome sequencing. In anticipation of advances in sequencing and its incorporation into clinical practice, AMP raised ethical and laboratory practice concerns for the Committee's consideration.

17 Jun 2010

Research studies may lead to future development of cell transplant therapy for ALS

The University of California, San Diego, The Salk Institute for Biological Studies and Life Technologies Corporation today announced the initiation of studies which may lead to the future development of cell transplant therapy for amyotrophic lateral sclerosis, also known as Lou Gehrig's disease. Currently, there is only one FDA-approved pharmaceutical addressing this lethal disease, which affects approximately 30,000 people in the United States.

17 Jun 2010

NuGEN launches Encore NGS Library/Multiplex Systems and Ovation 3'-DGE System

NuGEN®, the provider of innovative RNA and DNA amplification and sample preparation technologies for breakthrough genomic analysis, today announced the introduction of its Encore NGS Library/Multiplex Systems and the Ovation 3'-DGE System. Together with the Ovation RNA-Seq System, launched in 2009, NuGEN is continuing to provide life sciences researchers with innovative and versatile sample preparation reagents that enable a broad range of Next Generation Sequencing (NGS) applications through fast, simple and scalable workflows.

11 Jun 2010

Takara Bio to distribute NuGEN's solutions in Japan, South Korea, China

NuGEN, the provider of innovative RNA and DNA sample preparation technologies that enable breakthrough genomic analysis, today announced it has signed a non-exclusive agreement with Takara Bio to distribute the full spectrum of NuGEN's next-generation sequencing, microarray and q-PCR nucleic acid amplification and sample preparation products in Japan, South Korea and China. In addition, Takara is authorized to offer services using NuGEN products in the same territory.

9 Jun 2010

Mount Sinai School of Medicine deploys Isilon scale-out NAS for DNA sequencing and analysis workflow

Isilon® Systems today announced that Mount Sinai School of Medicine's Genomics Institute and Department of Genetics and Genomic Sciences has deployed Isilon scale-out NAS as the primary repository for its next-generation DNA sequencing and analysis workflow.

27 May 2010

Caliper to sell RapidTrace solid phase extraction and TurboVap evaporation product lines to Biotage for $16.5M

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today announced that it reached an agreement to sell its RapidTrace® solid phase extraction and TurboVap® evaporation product lines to Biotage AB for $16.5 million in cash.

18 May 2010

LifeCodexx AG develops test using Next Generation Sequencing technologies for prenatal diagnostics

LifeCodexx AG has started operational research and development work on clinically validated diagnostic tests by using Next Generation Sequencing technologies. The work currently focuses on the field of prenatal diagnostics.

12 May 2010

Iowa State University researcher works on faster method to detect salmonella from contaminated foods

Using technology available through a local company, an Iowa State University researcher is working on a faster method to detect and genetically identify salmonella from contaminated foods.

5 May 2010

Caliper Life Sciences' first-quarter 2010 GAAP revenues increase 1% to $28.7M

Caliper Life Sciences, Inc., today reported its first quarter 2010 results.

29 Apr 2010

Life Technologies first-quarter non-GAAP 2010 revenue increases 13% to $887 million

Life Technologies Corporation today announced results for its first quarter ending March 31, 2010. Non-GAAP revenue for the first quarter was $887 million, an increase of 13 percent over the $785 million reported for the first quarter of 2009. Excluding the impact of currency and completed acquisitions and divestitures, organic revenue for the quarter grew 10 percent over the same period in the previous year.

28 Apr 2010

Illumina announces shipment of HiScanSQ system for research needs

Illumina, Inc. today announced shipment of HiScanSQ, the first instrument to integrate microarray analysis and next-generation sequencing in a modular design that can evolve with changing research needs.

From Illumina, Inc. 27 Apr 2010

Fluidigm releases protocol for Access Array System for sequencing amplicon libraries

Fluidigm Corporation today announced the release of a protocol for the Access Array™ System that enables sequencing of amplicon libraries using GS FLX Titanium Series reagents on the 454 GS FLX sequencing system. The Access Array integrated fluidic circuit (IFC) automatically generates emPCR-ready libraries by simultaneously combining 48 samples and 48 primer sets to produce 48 uniquely-barcoded samples per chip for approximately $7 (U.S.) per sample.

27 Apr 2010

MMRC Multiple Myeloma Genomics Initiative presented at AACR 2010

An analysis of 38 myeloma tumor genomes surveyed through extensive next-generation sequencing by the Broad Institute has revealed intriguing recurrent mutations that point to important cellular pathways which contribute to multiple myeloma. These data were revealed during an oral presentation entitled "First Impressions of the Multiple Myeloma Genome" by Todd R. Golub, MD, Director of the Cancer Program at the Eli and Edythe L. Broad Institute.

21 Apr 2010

Ghent University signs agreement to use Roche's LightCycler 1536 Instrument for cancer research

Roche and Ghent University (Belgium) have signed an agreement for the use of Roche's LightCycler® 1536 Instrument in various cancer research projects in Ghent. Studies include multigene expression signature profiling on cancer research samples and, digital PCR for sensitive detection of mutant cancer cells in a background of normal cells.

21 Apr 2010

New web-based service for analyzing, visualizing and managing DNA sequencing data

DNAnexus, Inc. today announced the commercial launch of its web-based service for analyzing, visualizing, and managing next-generation DNA sequencing data. Andreas Sundquist, Ph.D., co-founder and CEO, will introduce the solution publicly for the first time today at the annual Bio-IT World Conference and Expo in Boston, Massachusetts.

20 Apr 2010

NextBio announces new Sequence-Centric module for mining high throughput array and sequencing data

NextBio today announced the latest evolution of its innovative life science research platform, adding new capabilities for the integration and mining of high-throughput array and next-generation sequencing data. The new NextBio Sequence-Centric module enables researchers to effectively explore and utilize massive amounts of public and internally generated sequencing data, while allowing organizations to create corporate-wide genomic data platforms to serve the needs of their global research teams.

20 Apr 2010

Radiolabeled hedgehog can differentiate stem-like cancer cells, identify aggressive tumors

At the American Association for Cancer Research 101st Annual Meeting 2010, scientists and clinicians will present more than 6,300 abstracts dealing with innovative aspects of biology, technology and emerging therapies.

19 Apr 2010

Amgen announces results from pivotal Phase 3 "408" trial of Vectibix

Amgen today announced detailed results from a new biomarker analysis of the pivotal Phase 3 "408" trial of Vectibix® (panitumumab) plus best supportive care compared to BSC alone. The analysis used massively parallel, next-generation sequencing technology to investigate whether mutations in nine genes known to be mutated in colorectal cancer, including the previously unanalyzed exon 3 mutation of the KRAS gene, are predictive of response to Vectibix in metastatic colorectal cancer.