RNA Sequencing News and Research

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Researchers develop comprehensive framework to classify small-cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have developed the first comprehensive framework to classify small-cell lung cancer (SCLC) into four unique subtypes, based on gene expression, and have identified potential therapeutic targets for each type in a study published today in Cancer Cell.

22 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

NK and T cell subsets show distinctive lung-homing receptor profiles in COVID-19 patients

A new study reveals in detail the changes that occur in peripheral blood natural killer (NK) and T cells in COVID-19.

18 Jan 2021

FAU researchers develop simplified, rapid SARS-CoV-2 detection protocol

To properly monitor and help curb the spread of COVID-19, several millions of diagnostic tests are required daily in just the United States alone.

13 Jan 2021

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

Bruker Corporation and Evosep today announced major progress in high-sensitivity, quantitative true single-cell proteomics, using a modified timsTOF Pro mass spectrometer connected to an Evosep One low-flow chromatography system.

From Bruker Daltonics 8 Jan 2021

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Researchers at the Icahn School of Medicine at Mount Sinai have identified three major molecular subtypes of Alzheimer's disease (AD) using data from RNA sequencing.

7 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Scientists develop a new method to study the molecular characteristics of T cells

UT Southwestern scientists have developed a new method to study the molecular characteristics of T cells, critical immune cells that recognize and attack invaders in the body such as viruses, bacteria, and cancer.

6 Jan 2021

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.

4 Jan 2021

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Stem cells in the brain divide over months to create new nerve cells

For the first time, scientists at the University of Zurich have been able to observe stem cells in the adult mouse brain that divide over the course of several months to create new nerve cells. The study shows that brain stem cells are active over a long period, and thus provides new insights for stem cell research.

21 Dec 2020

Cell atlas helps better understand the biology of tropical disease parasite

The first cell atlas of an important life stage of Schistosoma mansoni, a parasitic worm that poses a risk to hundreds of millions of people each year, has been developed by researchers at the Wellcome Sanger Institute and their collaborators.

18 Dec 2020

Mogrify solidifies IP position surrounding core technology and expands platform algorithm to enhance cell conversion

Mogrify today announced it had secured the assignment of the foundational intellectual property underpinning its core direct cell conversion technology.

17 Dec 2020

Researchers identify neurons that regulate nausea-like responses in mice

At some point, everyone experiences nausea. Whether it occurs after unwisely eating a week-old slice of pizza or as an accompaniment to a serious infection, that queasy, unsettling sensation centered around the stomach is a signal that something is amiss within the body and typically portends a bout of vomiting.

17 Dec 2020

RNA Sequencing News and Research

Researchers develop comprehensive framework to classify small-cell lung cancer

New computational technique accurately differentiates between data from tumor cells and normal cells

NK and T cell subsets show distinctive lung-homing receptor profiles in COVID-19 patients

FAU researchers develop simplified, rapid SARS-CoV-2 detection protocol

Bruker and Evosep announce major progress in unbiased, quantitative true single-cell proteomics

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Common gene expression changes at target tissues of four autoimmune diseases found

Scientists develop a new method to study the molecular characteristics of T cells

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Tissue healing after brain injury could spur tumor growth

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Stem cells in the brain divide over months to create new nerve cells

Cell atlas helps better understand the biology of tropical disease parasite

Mogrify solidifies IP position surrounding core technology and expands platform algorithm to enhance cell conversion

Researchers identify neurons that regulate nausea-like responses in mice

Researchers explain the role of enzyme that facilitates appropriate development of mouse embryo

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

Study offers new clues to the pathogenesis of glaucoma

Research breakthrough dispels concerns that human stem cells contain cancer-causing mutations

Networks of genes involved in congenital heart disease revealed

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