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UCLA study finds cost variation across entire care process for low-risk prostate cancer

Now, for the first time, UCLA researchers have described cost across an entire care process for low-risk prostate cancer - from the time a patient checks in for his first appointment to his post-treatment follow-up testing - using time-driven activity-based costing. And they found a wide variation in costs for the various available treatments that remained consistent over a 12-year period, indicating a better method to monitor costs could save valuable healthcare dollars, said study first author Dr. Aaron Laviana, a fifth year urology resident.

3 Nov 2015

TSRI scientists awarded NIH grant to investigate molecular machinery involved in cancer metastasis

Cancer metastasis occurs when tumor cells escape from a primary tumor, via the blood stream, and establish tumors in secondary locations. When the metastases are found in distant tissues and organs, doctors call this stage IV cancer, and the survival rate is low.

3 Nov 2015

Secret tunnels used by cancer cells can be exploited to deliver drug therapies, suggests new study

A new discovery published in the Nov. 2015 issue of The FASEB Journal shows that cancer cells use previously unknown channels to communicate with one another and with adjacent non-cancerous cells.

3 Nov 2015

Findings suggest potential metabolic pathway against cancer

When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don't have the weapons to kill the cancer.

3 Nov 2015

Common heart drug may halt progression of angiosarcoma

A common heart drug may stop the progression of angiosarcoma, a cancer of the inner lining of blood vessels, according to a study by researchers at Texas Tech University Health Sciences Center El Paso.

3 Nov 2015

Salk scientists uncover enzyme responsible for suppressing deadly lung cancer

Scientists at the Salk Institute have uncovered a molecule whose mutation leads to the aggressive growth of a common and deadly type of lung cancer in humans.

3 Nov 2015

Researchers identify tumor suppressor genes that drive subset of melanomas

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that appeared today in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas - one that is still seeing a rise in new cases. This gene is a newly identified member of a group of genes called tumor suppressor genes.

3 Nov 2015

Cancer DNA in patient's bloodstream could help deliver personalized treatment for liver cancer

Fragments of cancer DNA circulating in a patient's bloodstream could help doctors deliver more personalized treatment for liver cancer, Japanese researchers report.

2 Nov 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.

31 Oct 2015

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Analysis of tumor RNA carried in platelets - blood components best known for their role in clotting - may prove to be more useful than other "liquid biopsy" technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Women with elevated breast cancer risk can benefit from regular physical activity

Regular physical activity could play a role in helping women at high-risk of breast cancer delay the need for drastic preventive measures such as prophylactic mastectomy, according to new research led by the Perelman School of Medicine at the University of Pennsylvania.

30 Oct 2015

New clinical trial on breast cancer may help treat and control disease

A new clinical trial at Sanford Health is exploring how genetic changes that occur during breast cancer might help health care providers better identify, treat and control the disease.

30 Oct 2015

Halozyme Therapeutics announces initiation of rivipansel Phase 1 clinical trial

Halozyme Therapeutics, Inc. today announced that the first healthy subject has been dosed in a Phase 1 clinical trial evaluating the safety, tolerability and pharmacokinetics of a subcutaneous formulation of rivipansel, a compound discovered by GlycoMimetics, Inc. and being developed by Pfizer Inc., using Halozyme's ENHANZE formulation.

30 Oct 2015

Scientists explore biodegradable nanomedicine to destroy ovarian cancer cells left behind after surgery

Scientists are investigating a biodegradable nanomedicine that can selectively destroy ovarian cancer cells left behind after surgery. These findings are a step forward in the development of targeted therapies for hard-to-treat cancers. This work is being presented Oct. 29 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

29 Oct 2015

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

A new study from scientists at The Scripps Research Institute helps explain why cancer metastasis is so hard to stop.

29 Oct 2015

Tumor News and Research

UCLA study finds cost variation across entire care process for low-risk prostate cancer

TSRI scientists awarded NIH grant to investigate molecular machinery involved in cancer metastasis

Secret tunnels used by cancer cells can be exploited to deliver drug therapies, suggests new study

Findings suggest potential metabolic pathway against cancer

Common heart drug may halt progression of angiosarcoma

Salk scientists uncover enzyme responsible for suppressing deadly lung cancer

Researchers identify tumor suppressor genes that drive subset of melanomas

Cancer DNA in patient's bloodstream could help deliver personalized treatment for liver cancer

Key protein controls stem cell properties that could make them useful in regenerative medicine

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Prkci gene maintains balance in stem cell production

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Specialized type of immunotherapy can boost survival from pancreatic cancer

Women with elevated breast cancer risk can benefit from regular physical activity

New clinical trial on breast cancer may help treat and control disease

Halozyme Therapeutics announces initiation of rivipansel Phase 1 clinical trial

Scientists explore biodegradable nanomedicine to destroy ovarian cancer cells left behind after surgery

New TSRI study highlights urgent need for new treatments to fight growing cancer metastases

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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