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Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Researchers identify potential drug combination to treat uveal melanoma

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) have identified a potential drug combination to treat uveal melanoma, a type of eye cancer.

7 Dec 2020

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial.

6 Dec 2020

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

An analysis of lung tissues from patients with different types of pulmonary fibrosis - including cases triggered by COVID-19 - has revealed a promising molecular target to ameliorate the chronic and irreversible disease.

5 Dec 2020

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

Researchers from the Department of Biochemistry of RUDN University developed a wound-healing gel based on a substance that is produced by Trichoderma fungi.

5 Dec 2020

Matrix-induced autologous chondrocyte implantation shows comparable benefit to therapy alternatives

Autologous chondrocyte implantation (ACI) has been used in adults with deep cartilage defects for over 30 years and has been further developed and modified over time.

5 Dec 2020

Secukinumab for treatment of plaque psoriasis in children: Added benefit not proven

The monoclonal antibody secukinumab is approved for the treatment of moderate to severe plaque psoriasis in children and adolescents from the age of six years who are candidates for systemic therapy.

5 Dec 2020

Findings about primary cilia may be relevant for transplantation therapies in diabetes

A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets.

5 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Using gene therapy to achieve the positive health effects of physical exercise

Gene therapy is the most effective method to be able to provide health benefits you normally gain through physical exercise.

5 Dec 2020

Missing link between stress and infertility found

Otago researchers have found the "missing link between stress and infertility".

5 Dec 2020

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Affecting almost 600,000 people worldwide every year, and with only a 50% survival rate, oral squamous cell carcinoma (OSCC) is one of the more common and deadly forms of cancer.

4 Dec 2020

Exhaled breath can aid in the diagnosis of cancer

The air we exhale contains information that can assist with the diagnosis of disease. Researchers at the Fraunhofer Project Hub for Microelectronic and Optical Systems for Biomedicine MEOS are now developing solutions designed to enable the analysis of breath gas for this purpose. Although their research focuses on the early detection of cancer, the same principle could also be applied to distinguish between COVID-19 and other respiratory diseases.

4 Dec 2020

FRADE project offers effective help with fall prevention for the elderly

Senior citizens who are a little weaker or frail are often prone to falling. The FRADE concept of the Fraunhofer Center AICOS in Porto offers effective help with prevention. Sensor-based analysis of movements serves as a basis for a tailored training program. If the person actually falls, the system alerts the caregiver via text message. FRADE thus closes a major gap in health care.

4 Dec 2020

Low testosterone can increase risk of severe COVID-19 in males

Researchers from the USA and Saudi Arabia describe the direct correlation between testosterone levels, inflammatory cytokines, disease progression, and worse outcomes in male COVID-19 patients.

4 Dec 2020

A new potential therapy for Alzheimer's disease

A new potential therapeutic target for Alzheimer’s disease has been discovered by US researchers based at Case Western Reserve University.

4 Dec 2020

Study offers hope to parents and kids who face real danger from peanut exposure

It's a peanut-filled world--or at least it can feel that way for kids with peanut allergies. But a new study by researchers at the University of British Columbia and BC Children's Hospital gives hope to parents and kids who face real danger from exposure to peanuts.

3 Dec 2020

Study provides reassurance that patients and providers can use pharmacogenetic testing

A person's genetic make-up can influence whether they might experience side effects from certain medications.

3 Dec 2020

Therapy News and Research

Researchers identify new target that may lead to novel treatment for Alzheimer’s disease

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Researchers identify potential drug combination to treat uveal melanoma

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

Matrix-induced autologous chondrocyte implantation shows comparable benefit to therapy alternatives

Secukinumab for treatment of plaque psoriasis in children: Added benefit not proven

Findings about primary cilia may be relevant for transplantation therapies in diabetes

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

Using gene therapy to achieve the positive health effects of physical exercise

Missing link between stress and infertility found

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

Exhaled breath can aid in the diagnosis of cancer

FRADE project offers effective help with fall prevention for the elderly

Low testosterone can increase risk of severe COVID-19 in males

A new potential therapy for Alzheimer's disease

Study offers hope to parents and kids who face real danger from peanut exposure

Study provides reassurance that patients and providers can use pharmacogenetic testing

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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