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"Reparative" cardiac fibroblasts play key role in maintaining the mechanics of the heart

The researcher of the Faculty of Science of the UMA Adrián Ruiz-Villalba, who is also member of the Andalusian Center for Nanomedicine and Biotechnology (BIONAND) and the Biomedical Research Institute of Malaga (IBIMA), is the first author of an international study that has identified the heart cells in charge of repairing the damage caused to this organ after infarction.

13 Oct 2020

New study details how Michigan nursing homes limited the spread of coronavirus

Seven months ago, the nation first heard of a surge of COVID-19 deaths in a Washington nursing home – an early warning sign of how the coronavirus could rip through such facilities.

13 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

A new study published on the preprint server bioRxiv in October 2020 shows that a combination of a new compound GNS561 and remdesivir act synergistically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This suggests that autophagy inhibitors could be an alternative strategy for SARS-CoV-2 infection.

12 Oct 2020

Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

12 Oct 2020

Computational biology algorithm could help optimize culture conditions required for cell therapy

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders.

12 Oct 2020

HIV self-tests improve "door-to-door" testing campaigns

Despite significant progress in prevention and therapy, millions of people still get infected with HIV every year.

12 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Study highlights need for culturally relevant programs to educate Black communities on hepatitis B

Hepatitis B disproportionately impacts U.S. Blacks, including African American and Haitian Blacks. Both communities suffer from widespread misinformation and access to care issues that might avert disease detection and prevention, according to a study published in Cancer Causes & Control by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

12 Oct 2020

New study may lead to more effective, personalized cancer immunotherapies

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

12 Oct 2020

WVU receives $1.2 million to bring telehealth capabilities to rural emergency departments

Rural emergency departments often lack the medical specialists who staff larger, urban hospitals. Yet rural patients have the same conditions--and need the same prompt care--that people in cities do.

9 Oct 2020

New initiative identifies key parameters underlying effective anti-tumor immunity

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

9 Oct 2020

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

9 Oct 2020

Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

In June, two studies in Science reported an antibody cocktail against SARS-CoV-2 developed from studies in humanized mice and recovering patients. The two antibody cocktail was designed to bind the virus to reduce the risk of a drug-resistant form emerging.

9 Oct 2020

Researchers develop international policy index for HIV prevention among drug users

Peter Meylakhs, from HSE University - St. Petersburg, together with colleagues from Georgia State University (USA) and Tarbiat Modares University (Tehran), have developed the HIV-PWID Policy Index (HPPI)--an international policy index for HIV prevention among people who inject drugs.

9 Oct 2020

Study examines ways to improve prone positioning for severe ARDS during COVID-19 pandemic

A new study published online in the Annals of the American Thoracic Society examines ways to increase the use of prone positioning for patients with severe acute respiratory distress syndrome (ARDS), and develops specific implementation strategies that can assist in clinicians' response to the COVID-19 pandemic.

9 Oct 2020

Research investigates post-traumatic stress in partners following miscarriage

One in 12 partners experience post-traumatic stress after miscarriage, suggests a new study.The research, led by Imperial College London, surveyed over 100 couples who had experienced early stage pregnancy loss (miscarriage or ectopic pregnancy before 12 weeks).

9 Oct 2020

Novel radioimmunotherapy proven effective in reversing resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

8 Oct 2020

FDA awards six clinical trial research grants to enhance development of therapies for rare diseases

Today, the U.S. Food and Drug Administration announced that it has awarded six new clinical trial research grants to principal investigators from academia and industry totaling over $16 million over the next four years.

8 Oct 2020

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible are reviewed in the peer-reviewed journal Human Gene Therapy.

8 Oct 2020

Therapy News and Research

"Reparative" cardiac fibroblasts play key role in maintaining the mechanics of the heart

New study details how Michigan nursing homes limited the spread of coronavirus

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

Computational biology algorithm could help optimize culture conditions required for cell therapy

HIV self-tests improve "door-to-door" testing campaigns

A new therapeutic approach for Epstein-Barr virus-associated tumors

Study highlights need for culturally relevant programs to educate Black communities on hepatitis B

New study may lead to more effective, personalized cancer immunotherapies

WVU receives $1.2 million to bring telehealth capabilities to rural emergency departments

New initiative identifies key parameters underlying effective anti-tumor immunity

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

Antibody cocktail may offer clinical benefit in both prevention and treatment of COVID-19

Researchers develop international policy index for HIV prevention among drug users

Study examines ways to improve prone positioning for severe ARDS during COVID-19 pandemic

Research investigates post-traumatic stress in partners following miscarriage

Novel radioimmunotherapy proven effective in reversing resistance to lymphoma therapy

FDA awards six clinical trial research grants to enhance development of therapies for rare diseases

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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