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New approach to vaccine development is 97 per cent efficacious and could eliminate shingles

A new vaccine has proven almost completely effective in preventing shingles (disease medical name: herpes zoster), an extremely painful nerve infection which affects a third of Australians; most over the age of 50.

1 May 2015

Pembrolizumab effective, well-tolerated in advanced melanoma patients

Compared with ipilimumab, treatment with pembrolizumab not only significantly improves outcomes, but also results in fewer high-grade adverse events in patients with advanced melanoma, a phase III trial shows.

30 Apr 2015

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists at Texas Biomedical Research Institute have begun work on a nearly $3.4 million study funded by the National Institutes of Health over the next four years to create an attenuated, or weakened, virus that is a hybrid of the papilloma virus and the human immunodeficiency virus, with the potential to jumpstart a body's immune response to develop antibodies against both viruses.

30 Apr 2015

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

Eleven IFPMA member companies are involved in the development of new antibiotics. There are currently 34 antibacterial compounds in development (19 molecules and 15 vaccines). Eight compounds are undergoing the final stages of demonstrating their efficacy, quality, and safety (phase 3 clinical trials)...

30 Apr 2015

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

30 Apr 2015

MR Solutions demonstrates preclinical multi-modality imaging systems in Toronto

UK-based MR Solutions will be demonstrating its latest commercially available cryogen-free multi-modality preclinical MRI imaging systems at the 23rd Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)...

From MR Solutions 30 Apr 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter ended March 31, 2015. For the first quarter of 2015, the Company reported a net loss of $1.2 million, or $0.01 loss per share, compared to a net loss of $11.8 million, or $0.17 loss per share, for the same period in 2014.

30 Apr 2015

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

OncoGenex Pharmaceuticals, Inc. announced today it has filed an amendment with the U.S. Food and Drug Administration, as well as initiated filing with regulatory agencies in other countries, to amend the statistical design and analysis plan of its pivotal, international Phase 3 ENSPIRIT trial evaluating custirsen in the treatment of non-small cell lung cancer (NSCLC).

30 Apr 2015

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

Researchers at The University of Texas Health Science Center at Houston are helping to make precision medicine a reality by sequencing entire exomes of people to assess chronic disease risk and drug efficacy. The results of a study on this topic were published in Nature Genetics on Monday.

30 Apr 2015

Lung volume reduction surgery could improve lung function in emphysema patients

Emphysema is a chronic, progressive, obstructive lung disease in which the small sacs of the lung (alveoli) are destroyed, leading to air pockets and severe breathing difficulties. In 2011, 4.7 million Americans reported being diagnosed with emphysema, and in 2013 more than 8200 patients died from emphysema.

30 Apr 2015

Researchers examine alternative antimicrobials to lower bacterial contamination in fresh produce

Nearly half of foodborne illnesses in the U.S. from 1998 through 2008 have been attributed to contaminated fresh produce. Prevention and control of bacterial contamination on fresh produce is critical to ensure food safety. The current strategy remains industrial washing of the product in water containing chlorine. However, due to sanitizer ineffectiveness there is an urgent need to identify alternative antimicrobials, particularly those of natural origin, for the produce industry.

30 Apr 2015

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer.

30 Apr 2015

Oncologists need to screen tumor patients for depression

Because depression in brain cancer patients is a common but often overlooked condition, oncologists should regularly screen tumor patients for depression, according to an article in the current issue of CNS Oncology. The journal is published by Future Medicine, an imprint of Future Science Group.

30 Apr 2015

Montefiore and Einstein researchers to present data on obesity, asthma and autism at PAS 2015

Researchers from the Children's Hospital at Montefiore and Albert Einstein College of Medicine will present data from more than 50 studies that explore topics including obesity, asthma and autism at the annual meeting of the Pediatric Academic Societies.

29 Apr 2015

Emergency department-initiated treatment better than referrals for opioid-dependent patients

Yale researchers conducted the first known randomized trial comparing three treatment strategies for opioid-dependent patients receiving emergency care. They found that patients given the medication buprenorphine were more likely to engage in addiction treatment and reduce their illicit opioid use.

29 Apr 2015

Novel subdermal implant delivering potent ARV drugs shows promise in stopping HIV

Is the end of HIV near? Findings published this week in Antimicrobial Agents and Chemotherapy report that a novel, subdermal implant delivering potent antiretroviral (ARV) drugs shows extreme promise in stopping the spread of HIV.

29 Apr 2015

First new treatment authorised in a decade for advanced cervical cancer patients in the UK

The European Commission has licensed Avastin in combination with standard chemotherapy for the treatment of women with advanced cervical cancer. Until now, the treatment has been available ahead of licence to eligible patients in England via individual requests to the Cancer Drugs Fund (CDF).

28 Apr 2015

First patient enrolled in CryoLife's PerClot IDE clinical trial

CryoLife, Inc., a leading medical device and tissue processing company focused on cardiac and vascular surgery, announced today the enrollment of the first patient in its PerClot Investigational Device Exemption (IDE) clinical trial, the Company's pivotal clinical trial to gain approval to commercialize PerClot in the U.S.

28 Apr 2015

Preventive intervention improves knowledge, attitudes about sexual risk among adolescent boys than girls

Boys aged between 12-14 years old showed improved knowledge and attitudes about sexual risk after a preventive intervention, compared to girls of the same age, according to a study presented yesterday at the Pediatric Academic Societies Annual Meeting.

28 Apr 2015

Will new hepatitis C treatments strain payers’ budgets? An interview with Dr Chhatwal

Our analysis shows that these drugs would not save overall healthcare money, but would add to the budget. When something is cost effective, it does not necessarily mean it is going to save money. It essentially implies that we're willing to spend additional money to gain additional benefits...

28 Apr 2015

Efficacy News and Research

New approach to vaccine development is 97 per cent efficacious and could eliminate shingles

Pembrolizumab effective, well-tolerated in advanced melanoma patients

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

New research-based pharmaceutical industry report provides insights on how to slow down antimicrobial resistance (AMR) and boost antibiotic R&D

MR Solutions demonstrates preclinical multi-modality imaging systems in Toronto

Neurocrine reports net loss of $1.2 million for first quarter 2015

OncoGenex provides update on Phase 3 ENSPIRIT trial evaluating custirsen for treatment of NSCLC

UTHealth scientists use new methods to explore naturally occurring 'knockout humans'

Lung volume reduction surgery could improve lung function in emphysema patients

Researchers examine alternative antimicrobials to lower bacterial contamination in fresh produce

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Oncologists need to screen tumor patients for depression

Montefiore and Einstein researchers to present data on obesity, asthma and autism at PAS 2015

Emergency department-initiated treatment better than referrals for opioid-dependent patients

Novel subdermal implant delivering potent ARV drugs shows promise in stopping HIV

First new treatment authorised in a decade for advanced cervical cancer patients in the UK

First patient enrolled in CryoLife's PerClot IDE clinical trial

Preventive intervention improves knowledge, attitudes about sexual risk among adolescent boys than girls

Will new hepatitis C treatments strain payers’ budgets? An interview with Dr Chhatwal

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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