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Adimab initiates new independent research collaborations with Eli Lilly, Genentech, and Human Genome Sciences

Adimab, Inc., a technology leader in the discovery of fully human antibodies, today announced the initiation of three new independent research collaborations with Eli Lilly, Genentech, and Human Genome Sciences. Over the past 18 months Adimab has established collaborations with several leading Pharmaceutical companies including: Merck, Roche, Novartis, Pfizer, and now Eli Lilly, Genentech, and Human Genome Sciences.

16 Dec 2010

DeCODE Genetics identify SNPs to derive PSA threshold for diagnosing prostrate cancer

Scientists from deCODE genetics and academic colleagues from Iceland, the UK, US, Netherlands, Spain and Romania today report the discovery of a set of single-letter variations in the sequence of the human genome that impact individual baseline levels of prostate specific antigen, or PSA.

16 Dec 2010

Anoles key to medically applicable regeneration?

Anolis lizards first entered Arizona State University biologist Kenro Kusumi's life in 1980 when, as a member of a junior curator program, he recorded in his field notebook that he had found an Anolis egg on a field trip. Kusumi still has those notes, along with other memorabilia that document the influence that both his early life and more recent experiences have had on his current pursuits in developmental biology.

15 Dec 2010

Tumor suppressor p53 may serve as 'Guardian against Genome Reprogramming'

A close collaboration between researchers at the Salk Institute for Biological Studies and the Institute for Advanced Study found that the tumor suppressor p53, long thought of as the "Guardian of the Genome," may do more than thwart cancer-causing mutations. It may also prevent established cancer cells from sliding toward a more aggressive, stem-like state by serving as a "Guardian against Genome Reprogramming."

15 Dec 2010

Life Technologies announces launch of Ion Personal Genome Machine sequencer

Life Technologies Corporation, a provider of innovative life science solutions, today announced that it has launched its Ion Personal Genome Machine (PGM™) sequencer, the first product to use semiconductor sequencing technology. The sequencer is shipping to select sites in North America, Europe and Asia Pacific.

14 Dec 2010

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease.

14 Dec 2010

Novel labeling technique helps researchers to explore DNA chemical modification

Researchers at Emory University School of Medicine and the University of Chicago have developed a method for labeling and mapping a "sixth nucleotide," whose biological role scientists are only beginning to explore.

14 Dec 2010

Yissum introduces novel DNA profiling method for investigating complex crime scenes

Forensic DNA science has advanced significantly in the latest decade, and constitutes today the mainstay of forensic science. All serious crime scenes are routinely inspected for DNA evidence and many cases are solved by matching the DNA in the crime scene to that of a suspect. But often a crime scene will contain complex DNA mixtures (usually more than two individuals), and the detection of a particular DNA profile in such mixtures is challenging.

13 Dec 2010

ORNL's software scans molecular databases, may help scientists to develop new drug treatments

A quicker and cheaper technique to scan molecular databases developed at the Department of Energy's Oak Ridge National Laboratory could put scientists on the fast track to developing new drug treatments.

13 Dec 2010

Origin of Haiti cholera epidemic traced to South Asia

The strain of cholera currently sweeping through post-earthquake Haiti originated in South Asia, conclude scientists who did a rapid genetic analysis of bacteria collected from Haitian patients. The finding supports the notion that the cholera bacteria fueling the outbreak arrived on the island via recent visitors.

13 Dec 2010

Study finds Haitian cholera strain resembles one from South Asia, carries mutation that increases severity

"Detailed genetic tests confirm that the cholera strain that has killed more than 2,000 people in Haiti came from South Asia and most closely resembles a strain circulating in Bangladesh," according to a study published Thursday in the New England Journal of Medicine (NEJM), Reuters reports (12/9).

13 Dec 2010

Complete Genomics announces CNV and SV results as part of complete human genome sequencing service

Complete Genomics Inc. announced today that its customers will now receive copy number variation (CNV) and structural variation (SV) results as part of the CGA™ Service. This new enhancement includes additional types of variation data including quantitative, large-scale copy number measurements and larger inter- and intrachromosomal rearrangements.

10 Dec 2010

Ambry Genetics announces launch of Illumina HiSeq 2000 Next Generation Sequencing Services

Ambry Genetics, a global leader in genomic services to the healthcare and life sciences industries, announced today that it has officially launched their Illumina HiSeq 2000 Next Generation Sequencing Services. Ambry Genetics has been an early adapter of Illumina sequencing systems since 2007 and has extensive experience as a Certified Service Provider.

10 Dec 2010

Haitian cholera pathogen closely related to 'El Tor O1' variant from South Asia

Scientists from Pacific Biosciences of California, Inc. and Harvard Medical School have successfully employed single molecule, real-time (SMRT™) DNA sequencing technology to rapidly characterize the pathogen responsible for the recent deadly cholera epidemic in Haiti. Published online Thursday in the New England Journal of Medicine, the results provide the first whole genome sequence analysis and most detailed genetic profile to date of the Haitian Vibrio cholerae outbreak strain.

10 Dec 2010

VCP gene causes some instances of familial ALS: Researchers

Using a new gene sequencing method, a team of researchers led by scientists from Johns Hopkins and the National Institutes of Health has discovered a gene that appears to cause some instances of familial amyotrophic lateral sclerosis. The finding could lead to novel ways to treat the more common form of this fatal neurodegenerative disease, which kills the vast majority of the nearly 6,000 Americans diagnosed with ALS every year.

10 Dec 2010

Scientists determine 500 three-dimensional protein structures from bacterial and protozoan pathogens

Scientists at Seattle Biomedical Research Institute and Northwestern University Feinberg School of Medicine have reached a major milestone in the effort to wipe out some of the most lethal diseases on the planet.

9 Dec 2010

Walter and Eliza Hall Institute researcher awarded 2011 Gani Medal for Human Genetics

Major advances in our understanding of human evolution have seen Walter and Eliza Hall Institute researcher Dr Alicia Oshlack awarded the 2011 Gani Medal for Human Genetics by the Australian Academy of Science.

9 Dec 2010

Cellectis bioresearch announces winner of The Genome Customization Award

Cellectis bioresearch, a specialist in genome customization and a subsidiary of Cellectis (Alternext: ALCLS), has today announced the recipient of its post-doctoral fellowship award program. The Genome Customization Award (TGCA) is going to Dr Nelson Lau's research group, from the Department of Biology at the Brandeis University (Waltham, Massachusetts).

9 Dec 2010

OMT announces new human antibody platform using genetically engineered rats expressing human antibodies

Open Monoclonal Technology, Inc. (OMT) today announced its new human antibody platform using the first genetically engineered rats expressing a human antibody repertoire. The company, which also created the first targeted knockout rats in 2009, is now cross-breeding the knockout animals with the rats expressing human antibodies to finalize its platform.

9 Dec 2010

ChipDX validates genetic signature for early-stage colon cancer

ChipDX LLC, a New York-based online molecular diagnostics and personalized medicine company, discovered and validated a genetic signature for early-stage colon cancer and is developing an online screening application to enable clinicians to more accurately identify risk of recurrence. In the study, published in the December issue of the British Journal of Cancer, ChipDX demonstrates how the 163-gene signature stratifies colon cancer patients into high- and low-risk groups for recurrence with greater accuracy than current methods.

8 Dec 2010

Genome News and Research

Adimab initiates new independent research collaborations with Eli Lilly, Genentech, and Human Genome Sciences

DeCODE Genetics identify SNPs to derive PSA threshold for diagnosing prostrate cancer

Anoles key to medically applicable regeneration?

Tumor suppressor p53 may serve as 'Guardian against Genome Reprogramming'

Life Technologies announces launch of Ion Personal Genome Machine sequencer

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

Novel labeling technique helps researchers to explore DNA chemical modification

Yissum introduces novel DNA profiling method for investigating complex crime scenes

ORNL's software scans molecular databases, may help scientists to develop new drug treatments

Origin of Haiti cholera epidemic traced to South Asia

Study finds Haitian cholera strain resembles one from South Asia, carries mutation that increases severity

Complete Genomics announces CNV and SV results as part of complete human genome sequencing service

Ambry Genetics announces launch of Illumina HiSeq 2000 Next Generation Sequencing Services

Haitian cholera pathogen closely related to 'El Tor O1' variant from South Asia

VCP gene causes some instances of familial ALS: Researchers

Scientists determine 500 three-dimensional protein structures from bacterial and protozoan pathogens

Walter and Eliza Hall Institute researcher awarded 2011 Gani Medal for Human Genetics

Cellectis bioresearch announces winner of The Genome Customization Award

OMT announces new human antibody platform using genetically engineered rats expressing human antibodies

ChipDX validates genetic signature for early-stage colon cancer

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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