Immune System News and Research

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Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

An international team led by researchers from the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health, and Fred Hutchinson Cancer Research Center have used cutting edge genomic methods to uncover key biological insights that help explain the protective effects of the world's most advanced malaria vaccine candidate, RTS,S/AS01 (RTS,S).

22 Oct 2015

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

NHS Blood and Transplant will start producing stem cells for groundbreaking treatment aimed at combating one of the most serious health problems facing the NHS, diabetic kidney disease.

22 Oct 2015

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Dietary fatty acids affect the development and progression of autoimmune chronic-inflammatory diseases such as multiple sclerosis. In a collaborative study between the Departments of Neurology at the Ruhr-Universität Bochum (St. Josef-Hospital) and the Friedrich Alexander Universtiy Erlangen, researchers now found that long-chain fatty acids promote the development and propagation of CNS reactive immune cells in the intestinal wall. On the contrary, short-chain fatty acids promote the development and propagation of regulatory cells in the immune system.

22 Oct 2015

First primate model can help researchers to study mother-to-fetus CMV infections

Cytomegalovirus (CMV) is the leading infectious cause of birth defects worldwide, but scientists have been frustrated in their efforts to develop a vaccine to protect against infections.

20 Oct 2015

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

Scientists at The Scripps Research Institute have found a way to change leukemia cells into leukemia-killing immune cells. The surprise finding could lead to a powerful new therapy for leukemia and possibly other cancers.

20 Oct 2015

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Identifying a patient's genetic mutation led University of Arkansas for Medical Sciences (UAMS) physician-researcher Ling Gao, M.D., Ph.D., to an existing drug that eliminated the patient's stage IV Merkel-cell carcinoma. Gao's findings, made in collaboration with two other UAMS researchers, were published today in The New England Journal of Medicine.

19 Oct 2015

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

19 Oct 2015

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

19 Oct 2015

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

The key to immune-based cancer therapies lies in the ability to exploit some weakness within the tumor and its environment or to elude cancer's offenses. Writing in the journal Scientific Reports, researchers led by a group from the Roswell Park Cancer Institute Center for Immunotherapy have shared new insights about a subset of T cells that appear to do both those things, inhibiting cancer growth at the same time that they enhance the tumor-killing powers of other immune cells.

19 Oct 2015

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating blood cells and opens up a new avenue for reducing their progressive functional decline with age.

16 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.

16 Oct 2015

Genomic analysis confirms sexual transmission of Ebola virus in Liberia

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR).

16 Oct 2015

Sanofi Pasteur, IDRI establish Global Health Vaccine Center of Innovation

In an effort to accelerate timelines and decrease development costs of life-saving vaccines, the Infectious Disease Research Institute (IDRI) and Sanofi Pasteur today announce the establishment of the Global Health Vaccine Center of Innovation (GHVCI), to be headquartered at IDRI in Seattle.

16 Oct 2015

Researchers successfully convert skin cells into fully functional placenta-generating cells

Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs in the human body through cellular transplantation. Embryonic stem cells (ESCs) are pluripotent cells that are capable of long-term growth, self-renewal, and can give rise to every cell, tissue and organ in the fetus's body.

15 Oct 2015

Sleep deprivation can impact outcome of stem cell transplantation, study finds

Drowsy mice make poor stem cell donors, according to a new study by researchers at the Stanford University School of Medicine.

15 Oct 2015

Neutrophils kill invading microorganisms, starve microbes to death

The most frequent immune cells in the human blood, so-called neutrophils, efficiently kill invading microorganisms and slowly starve microbes to death by removing crucial trace elements. This is shown by researchers from Umeå University in Sweden in a study published in a special issue of Metallomics.

15 Oct 2015

Poorly-designed animal study threatens validity of preclinical research

Badly designed studies may lead to the efficacy of drugs being overestimated and money being wasted on trials that prove fruitless, according to new a study from McGill University in Canada.

15 Oct 2015

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

Human breast milk, which provides essential nutrients and antibodies to newborns, has long been known to play an important role in infant development and the immune system. In a new study published in Mucosal Immunology, researchers from Brigham and Women's Hospital report that human breast milk serves as a reservoir for bio-molecules that help to resolve inflammation and combat infection.

15 Oct 2015

OncoSec reports net loss of $6.5 million for fourth quarter of fiscal 2015

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced financial results for the fourth quarter and fiscal year ended July 31, 2015.

15 Oct 2015

Immune System News and Research

Researchers use cutting edge genomic methods to explain protective effects of malaria vaccine candidate

NHS to produce unique stem cells that could revolutionize treatment for diabetic kidney disease

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

First primate model can help researchers to study mother-to-fetus CMV infections

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

New research raises hope for novel cancer immunotherapy

Hiroshima University researchers demonstrate how Sendai virus escapes host immune system

Genomic analysis confirms sexual transmission of Ebola virus in Liberia

Sanofi Pasteur, IDRI establish Global Health Vaccine Center of Innovation

Researchers successfully convert skin cells into fully functional placenta-generating cells

Sleep deprivation can impact outcome of stem cell transplantation, study finds

Neutrophils kill invading microorganisms, starve microbes to death

Poorly-designed animal study threatens validity of preclinical research

Bio-molecules present in human breast milk can help resolve inflammation, combat infection

OncoSec reports net loss of $6.5 million for fourth quarter of fiscal 2015

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