Immune System News and Research

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Researchers develop novel computational approach to accelerate search for hepatitis C vaccine

Borrowing from several statistical science models, an interdisciplinary team of researchers from the University of Illinois at Urbana-Champaign has developed a novel computational approach for massively accelerating the search for a hepatitis C vaccine.

1 Dec 2015

Taking estriol along with conventional medications helps RRMS patients avoid relapses

Taking the pregnancy hormone estriol along with their conventional medications helped patients with relapsing-remitting multiple sclerosis (RRMS) avoid relapses, according to results of a Phase II randomized, placebo-controlled study led by UCLA researchers.

1 Dec 2015

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

A large multi-center clinical trial has found that a combination of antiviral medications can eradicate hepatitis C infection in more than 90 percent of patients with advanced liver disease. Known as the ASTRAL-4 trial, the study was co-led by investigators at Beth Israel Deaconess Medical Center and Intermountain Medical Center and published online Nov. 17 in The New England Journal of Medicine.

1 Dec 2015

Research sheds light on genetic factors involved in autoimmune diseases

A collaboration between researchers at the Babraham Institute and the University of Manchester has mapped the physical connections occurring in the genome to shed light on the parts of the genome involved in autoimmune diseases. Using a new technique, called Capture Hi-C, the team revealed novel insights into how changes in the genetic sequence have a biological effect and increase the risk of disease.

30 Nov 2015

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted approval for Empliciti (elotuzumab) in combination with two other therapies to treat people with multiple myeloma who have received one to three prior medications.

30 Nov 2015

Personalised peptide vaccination promising in bladder cancer

Metastatic bladder cancer patients who have progressed on first-line platinum-based chemotherapy could derive survival benefits from personalised peptide vaccination, according to phase II trial results.

27 Nov 2015

Incidence of HIV in Europe reaches record high

Results of recent surveillance conducted by the European Centre for Disease Prevention and Control (ECDC) and the WHO Regional Office for Europe indicate that the annual number of newly diagnosed HIV infections in Europe reached an all-time high in 2014.

27 Nov 2015

New combination approach to eradicate established tumors

A laboratory study conducted at Leiden University Medical Center in the Netherlands has found that immunotherapy can be efficiently combined with photodynamic therapy (PDT) to eradicate established tumors. The approach results in strong local tumor destruction and a robust systemic immune response against the disease.

27 Nov 2015

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. Researchers from the University and University Hospital Basel have now for the first time successfully combined such an antibody-drug conjugate with a therapy that stimulates the immune system to attack tumor cells.

26 Nov 2015

Study points to new avenue for developing potential strategies to thwart HIV virus

Nearly 37 million people worldwide are living with HIV. When the virus destroys so many immune cells that the body can't fight off infection, AIDS will develop. The disease took the lives of more than a million people last year.

26 Nov 2015

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Investigators at Montreal's Lady Davis Institute at the Jewish General Hospital and McGill University Health Centre have announced the start of a landmark clinical study aimed at restoring normal insulin secretion in people with longstanding type 1 diabetes.

26 Nov 2015

Purdue researchers develop products and processes to improve detection, treatment of diabetes

Food gatherings at Thanksgiving and Christmas require rigorous management by people affected by diabetes. Type 1 diabetes, also known as juvenile diabetes, is the result of the breakdown of insulin-producing cells in the pancreas. Type 2 diabetes can be the result of a combination of obesity, high caloric intake and a sedentary lifestyle.

26 Nov 2015

Seqirus announces FDA approval of Fluad for seasonal influenza

Seqirus announced today that the US Food and Drug Administration has approved Fluad (Influenza Vaccine, Adjuvanted) to help protect those aged 65 years and older against seasonal influenza. Fluad is the first adjuvanted seasonal influenza vaccine approved in the United States; it was specifically developed for the adult population aged 65 and older.

25 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

People with bipolar disorder have lower levels of certain omega-3 fatty acids that cross the blood-brain barrier compared to those who do not, according to researchers from Penn State College of Medicine and the National Institutes of Health. The finding could have implications for dietary interventions for the disorder.

25 Nov 2015

Risk of developing visceral leishmaniasis much higher in transplant patients

Researchers from Spain have analysed the prevalence of leishmaniasis among the population of organ transplant recipients. The findings of this study, published in the journal 'PLoS Neglected Tropical Disease', confirm that the risk of developing visceral leishmaniasis ‑the most severe form of the disease which can pose life-threatening complications‑ is more than one hundred times greater in transplant patients living in areas of disease outbreak.

25 Nov 2015

UF Health researcher finds simple way to treat immune-related disorder in mice

A University of Florida Health researcher has found a simple, rapid way to treat an immune-related disorder in mice, an approach that could eventually help multiple sclerosis patients after further research.

25 Nov 2015

Researchers offer novel solution to promote successful radiotherapy for cancer patients

Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal Nature Immunology, they offer a novel solution to promote successful radiotherapy for the millions of cancer patients who are treated with it.

25 Nov 2015

First seasonal influenza vaccine containing adjuvant now approved by FDA

The U.S. Food and Drug Administration today approved Fluad, the first seasonal influenza vaccine containing an adjuvant. Fluad, a trivalent vaccine produced from three influenza virus strains (two subtype A and one type B), is approved for the prevention of seasonal influenza in people 65 years of age and older.

25 Nov 2015

T1DM therapeutics market expected to reach $7.1 billion by 2021

Analysis from business intelligence provider GBI Research - Type 1 Diabetes Mellitus Therapeutics in Major Developed Markets to 2021 - states that the global market value for T1DM treatment will rise from $4.2 billion in 2014 to $7.1 billion by 2021, at a robust Compound Annual Growth Rate (CAGR) of 7.9%.

24 Nov 2015

Immune System News and Research

Researchers develop novel computational approach to accelerate search for hepatitis C vaccine

Taking estriol along with conventional medications helps RRMS patients avoid relapses

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

Research sheds light on genetic factors involved in autoimmune diseases

FDA grants approval for Empliciti (elotuzumab) to treat patients with multiple myeloma

Personalised peptide vaccination promising in bladder cancer

Incidence of HIV in Europe reaches record high

New combination approach to eradicate established tumors

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

Study points to new avenue for developing potential strategies to thwart HIV virus

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Purdue researchers develop products and processes to improve detection, treatment of diabetes

Seqirus announces FDA approval of Fluad for seasonal influenza

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

Risk of developing visceral leishmaniasis much higher in transplant patients

UF Health researcher finds simple way to treat immune-related disorder in mice

Researchers offer novel solution to promote successful radiotherapy for cancer patients

First seasonal influenza vaccine containing adjuvant now approved by FDA

T1DM therapeutics market expected to reach $7.1 billion by 2021

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