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Zika virus can mutate to become more infective and dangerous, finds study

LA JOLLA, CA - Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective - and potentially break through pre-existing immunity.

13 Apr 2022

Bioprinting for bone repair enhanced with two growth factor encoding genes

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

13 Apr 2022

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers demonstrated the evolution of multi-system inflammatory syndrome in children (MIS-C) following acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

12 Apr 2022

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S)-specific cluster of differentiation 8 (CD8+) T cell responses.

12 Apr 2022

PFAS exposure associated with increased risk of developing diabetes in midlife women

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that exposure to per- and polyfluoroalkyl substances (PFAS) - a large and diverse group of industrial chemicals found in many everyday products - is associated with an increased risk of developing diabetes in midlife women.

12 Apr 2022

Dysregulated retroelements associated with autoimmunity in COVID-19

Researchers investigate potential interactions between retro-elements shared between the human and coronavirus genomes.

12 Apr 2022

Harnessing electricity to treat certain types of cancer

Electricity has formed the basis of many aspects of the modern world, from providing reliable sources of light to powering home appliances and computers.

12 Apr 2022

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations.

12 Apr 2022

Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

Nemours Children's Health researchers have received two grants from the National Institutes of Health (NIH) totaling $5 million.

12 Apr 2022

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

CoVac-1, a new vaccine against SARS-CoV-2, induced T-cell immune responses in 93 percent of patients with B-cell deficiencies, including many patients with leukemia and lymphoma, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

12 Apr 2022

Researchers discover new way to inhibit key mutated gene underlying tumor growth

CU Boulder researchers have discovered a new way to inhibit the most commonly mutated gene underlying human tumor growth, opening the door to new therapeutic strategies for cancer and a host of other diseases.

12 Apr 2022

Aprotinin could inhibit virus replications by preventing SARS-CoV-2 entry into host cells

A clinical study from Spain recently confirmed laboratory experiments made by researchers of Goethe University Frankfurt and University of Kent who showed that the protease inhibitor aprotinin prevented cells to be infected by SARS-CoV2.

12 Apr 2022

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Researchers in Australia have evaluated the vaccine candidature of HexaPro S protein subunit vaccine against SARS-CoV-2.

12 Apr 2022

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

They might look like cells and act like cells. But a new potential COVID-19 treatment is actually a cleverly disguised trickster, which attracts viruses and binds them, rendering them inactive.

12 Apr 2022

Researchers construct first single-cell atlas of postnatal lung development in humans and mice

How do the lungs develop after taking their first breaths outside the womb? What cellular events and changes early in life give rise to lung malfunction and disease? To help answer these questions, scientists have constructed the first single-cell atlas of postnatal lung development in humans and mice.

12 Apr 2022

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

In a new study, researchers quantified the serological responses following the third dose of mRNA-based COVID-19 vaccines in patients with hematological malignancies.

12 Apr 2022

Researchers elucidate how ovarian tumors defy immunotherapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators at La Jolla Institute for Immunology and elsewhere, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.

12 Apr 2022

Experimental tool can precisely pick out interactions between immune cell and target antigen

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells' ability to recognize harmful microbes is critical to successfully fighting off infection.

12 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Researchers evaluated the immunogenicity of Pfizer’s BNT162b2 and Moderna’s mRNA-1273 vaccines offered as the fourth dose against SARS-CoV-2.

12 Apr 2022

B Cell News and Research

Zika virus can mutate to become more infective and dangerous, finds study

Bioprinting for bone repair enhanced with two growth factor encoding genes

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

PFAS exposure associated with increased risk of developing diabetes in midlife women

Dysregulated retroelements associated with autoimmunity in COVID-19

Harnessing electricity to treat certain types of cancer

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Nemours Children’s Health scientists receive two NIH grants to advance pediatric cancer research

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

Researchers discover new way to inhibit key mutated gene underlying tumor growth

Aprotinin could inhibit virus replications by preventing SARS-CoV-2 entry into host cells

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

Researchers construct first single-cell atlas of postnatal lung development in humans and mice

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

Researchers elucidate how ovarian tumors defy immunotherapy

Experimental tool can precisely pick out interactions between immune cell and target antigen

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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