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Study shows favorable cardiovascular health lowers risk of dementia

Genes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. researchers including Sudha Seshadri, MD, and Claudia Satizabal, PhD, of The University of Texas Health Science Center at San Antonio (UT Health San Antonio) reported July 20 in the journal Neurology.

21 Jul 2020

Ten major risk factors for Alzheimer's disease

Researchers have collated available scientific evidence on risk factors associated with Alzheimer's disease and come up with a list of ten important ones.

21 Jul 2020

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

20 Jul 2020

Researchers visualize DNA G-quadruplex formation in live cells for the first time

The formation of four-stranded DNA has been tracked in living human cells, allowing scientists to see how it works, and its possible role in cancer.

20 Jul 2020

Researchers identify underlying mechanism for metabolic memory and diabetic complications

For people with diabetes, vascular complications like kidney disease and atherosclerosis, which can lead to poor health and even death, are seen at increased rates.

20 Jul 2020

COVID-19 vaccine displays protective traits in nonhuman primates

A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus.

20 Jul 2020

Prostate tumors reactivate dormant molecular program during metastatic progression

When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute.

20 Jul 2020

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

A phase 2 trial of an Ad5 vectored COVID-19 vaccine candidate, conducted in China, has found that the vaccine is safe and induces an immune response, according to new research published in The Lancet.

20 Jul 2020

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet.

20 Jul 2020

Study shows feasibility of using cardiovascular risk screening tool in outpatient gynecology setting

A new study has shown that although 86% of women seen at an outpatient gynecology clinic had a cardiovascular risk factor and 40.1% had at least one cardiovascular symptom, the awareness of cardiovascular risk factors and symptoms was low.

20 Jul 2020

$Genetic markers can improve screening for osteoporotic fracture risk$

Genetic markers can improve screening for osteoporotic fracture risk

A new study shows that genetic pre-screening could reduce the number of screening tests needed to identify individuals at risk for osteoporotic fractures. Douglas P. Kiel, M.D., M.P.H., director of the Musculoskeletal Research Center in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, is an author on the report published this month in PLOS (Public Library of Science) Medicine.

20 Jul 2020

Developing a Better Understanding of Polycystic Ovary Syndrome (PCOS)

In this interview, Dr. Andrea Dunaif talks to News-Medical about their genetic analysis study which suggests there are different subtypes of PCOS.

20 Jul 2020

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Previous reports have shown that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), has been found in untreated wastewater. While the data is limited, there are no reported cases of a person becoming infected with the virus due to exposure to contaminated water.

20 Jul 2020

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

The coronavirus pandemic is still rapidly spreading across the globe, infecting more than 14.44 million people. With more than 188 countries and territories affected, scientists are racing to develop a vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

19 Jul 2020

How to decide whether or not to start treatment for prostate cancer?

You have been diagnosed with prostate cancer and your doctor gives you the option of not being treated, but of remaining under observation: is there any objective way you can decide to be treated or not treated? What should you do?

19 Jul 2020

Hybrid fungus involved in lung infections discovered

Aspergillus latus, a species of fungus previously found only in soil or plants, has been found for the first time in a hospital environment by an international group of researchers.

19 Jul 2020

Type 1 interferon deficiency as a biomarker for detecting patients at risk of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

17 Jul 2020

Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

A recently discovered hypercompact CRISPR enzyme found only in huge bacteriophages, and known as CRISPR-CasΦ, is functional, a new study by Patrick Pausch, Jennifer Doudna and colleagues reports, and it provides a powerful new tool in the CRISPR genome editing toolbox, including because it can target a wider range of genetic sequences compared to Cas9 and Cas12.

17 Jul 2020

New insight into the SARS-CoV-2 infection process

Canadian researchers from the Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, have found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be using a unique method to gain entry into the cells.

16 Jul 2020

Researchers unravel key mechanisms behind the mysteries of aging

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

16 Jul 2020

Genetic News and Research

Study shows favorable cardiovascular health lowers risk of dementia

Ten major risk factors for Alzheimer's disease

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

Researchers visualize DNA G-quadruplex formation in live cells for the first time

Researchers identify underlying mechanism for metabolic memory and diabetic complications

COVID-19 vaccine displays protective traits in nonhuman primates

Prostate tumors reactivate dormant molecular program during metastatic progression

China's Ad5 vectored COVID-19 vaccine safe and induces immune response

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Study shows feasibility of using cardiovascular risk screening tool in outpatient gynecology setting

Genetic markers can improve screening for osteoporotic fracture risk

Developing a Better Understanding of Polycystic Ovary Syndrome (PCOS)

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Oxford University and AstraZeneca to publish eagerly-anticipated COVID-19 trial results today

How to decide whether or not to start treatment for prostate cancer?

Hybrid fungus involved in lung infections discovered

Type 1 interferon deficiency as a biomarker for detecting patients at risk of severe COVID-19

Newly identified enzyme provides a new tool in CRISPR genome editing toolbox

New insight into the SARS-CoV-2 infection process

Researchers unravel key mechanisms behind the mysteries of aging

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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