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MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Massachusetts General Hospital investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer.

7 Jul 2016

Clinical trial to test low-dose heparin treatment for patients with ruptured brain aneurysm

A Louisville patient is the first to be enrolled in a national clinical trial to test a new treatment for patients who have suffered a ruptured brain aneurysm.

7 Jul 2016

Hippocampal inflammation linked to depressive symptoms in patients with multiple sclerosis

Patients with multiple sclerosis have higher rates of depression than the general population, including people with other life-long disabling diseases. Symptoms of multiple sclerosis arise from an abnormal response of the body's immune system.

7 Jul 2016

Research sheds new light on development of chronic inflammatory diseases

Research from life scientists at The University of Manchester has shone new light on the way cells tune in to different inflammatory signals to understand what is happening in the body.

7 Jul 2016

Daclizumab drug offers new treatment option for people living with relapsing forms of MS in the UK

A new, first-in-class treatment which is believed to use a double-action approach to fight MS by rebalancing the immune system, has today been authorised in the UK for people living with relapsing forms (the most common type) of the disease.

7 Jul 2016

Loyola among first health systems to offer absorbable stent to heart patients

Loyola Medicine will be among the first health systems in the country to offer heart patients a new stent that is absorbed by the body once it has served its purpose.

7 Jul 2016

Existing anti-inflammatory drugs may be effective in treating epilepsy

In epileptic patients, seizures lead to an increased level of inflammation-related proteins called chemokines in the brain, and systemic inflammation likely helps trigger and promote the recurrence of seizures, making inflammation a promising new target for anticonvulsant therapy.

6 Jul 2016

Sleep disturbances, long sleep duration linked to inflammatory illnesses

A new meta-analysis in Biological Psychiatry reports that sleep disturbances and long sleep duration are associated with increases in markers of inflammation.

6 Jul 2016

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

For more than five years, urine and cerebral-spinal fluid samples from patients with Parkinson's disease have been locked in freezers in the NINDS National Repository, stored with the expectation they might someday help unravel the still-hidden course of this slow-acting neurodegenerative disease.

6 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

Anaemia in heart failure may impact prognosis

Anaemia is common in patients with heart failure, regardless of the underlying phenotype, and is often associated with iron deficiency, UK researchers report.

6 Jul 2016

Scientists use novel brainstem model to determine how the brain controls breathing

Scientists from Karolinska Institutet, Sweden, have discovered how the brain controls our breathing in response to changing oxygen and carbon dioxide levels in the blood.

5 Jul 2016

Scientists identify genetic mutations linked to synchronous colorectal cancers

Researchers have identified genetic mutations affecting the immune system which may lead to the development of more than one bowel tumour at the same time. Understanding how these cancers develop could improve targeting of therapies, according to the study published in Nature Communications.

5 Jul 2016

Endometrial scratching in women appears to increase chance of clinical pregnancy, live birth

There is a much disputed claim that "injury" to the lining of the uterus - whether inadvertent or deliberate - increases the chance of embryo implantation and thus the chance of pregnancy in certain groups of women having IVF.

4 Jul 2016

Study finds link between copper exposure and prion protein neurotoxicity

Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion proteins.

4 Jul 2016

Inhalable ibuprofen holds potential to treat cystic fibrosis

Ibuprofen: You can buy it at any drug store, and it will help with that stabbing headache or sprained ankle. One of the ways it does so is by reducing inflammation, and it is this property that may also help patients with cystic fibrosis.

4 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

Scientists develop light-activated injectable device to stimulate nerve cells

In the campy 1966 science fiction movie "Fantastic Voyage," scientists miniaturize a submarine with themselves inside and travel through the body of a colleague to break up a potentially fatal blood clot. Right. Micro-humans aside, imagine the inflammation that metal sub would cause.

4 Jul 2016

Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

The secret ingredient is in the flour, but its impact lies within the gut. Adding resistant starch to the diets of people with metabolic syndrome can improve bacteria in the gut, according to research from South Dakota State University.

1 Jul 2016

Itaconate can suppress pro-inflammatory activity of macrophages

An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages - specific cells of immune system.

1 Jul 2016

Inflammation News and Research

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients

Clinical trial to test low-dose heparin treatment for patients with ruptured brain aneurysm

Hippocampal inflammation linked to depressive symptoms in patients with multiple sclerosis

Research sheds new light on development of chronic inflammatory diseases

Daclizumab drug offers new treatment option for people living with relapsing forms of MS in the UK

Loyola among first health systems to offer absorbable stent to heart patients

Existing anti-inflammatory drugs may be effective in treating epilepsy

Sleep disturbances, long sleep duration linked to inflammatory illnesses

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Anaemia in heart failure may impact prognosis

Scientists use novel brainstem model to determine how the brain controls breathing

Scientists identify genetic mutations linked to synchronous colorectal cancers

Endometrial scratching in women appears to increase chance of clinical pregnancy, live birth

Study finds link between copper exposure and prion protein neurotoxicity

Inhalable ibuprofen holds potential to treat cystic fibrosis

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

Scientists develop light-activated injectable device to stimulate nerve cells

Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

Itaconate can suppress pro-inflammatory activity of macrophages

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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