Antibodies News and Research

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PDL BioPharma's European patent claims upheld

PDL BioPharma has announced that the Opposition Division of the European Patent Office decided at an oral proceeding to uphold claims in the company's European Patent No. 0 451 216 ('216 patent) that are virtually identical to the claims remitted to the Opposition Division by the Board of Appeal.

25 Apr 2007

Gold nanoparticles for early detection of cancer

By attaching gold nanoparticles - like tiny balls or rods- to cancer cells, earlier detection will be possible.

24 Apr 2007

Chitin compound causes allergic inflammation

The beetle's back and the crab's shell owe their toughness to a common compound called chitin that now appears to trigger airway inflammation and possibly asthma, UCSF scientists have found.

24 Apr 2007

Key to understanding all biological processes is recognition

A human body has more than 10 to the power of 27 molecules with about one hundred thousand different shapes and functions.

24 Apr 2007

Study links Helicobacter pylori to asthma prevention

The stomach bacterium Helicobacter pylori, which causes stomach cancer and peptic ulcers, may not be all bad.

24 Apr 2007

Green tea may help protect against Sjogren's syndrome

They found significantly less salivary gland damage in a group treated with green tea extract, suggesting a reduction of the Sjogren's symptom commonly referred to as dry mouth. Dry mouth can also be caused by certain drugs, radiation and other diseases.

20 Apr 2007

Lexicon-Genentech reveals potential therapeutic targets

Lexicon Genetics Incorporated has announced that data was presented highlighting potential therapeutic targets related to its collaboration with Genentech, Inc. at the Society for Biomolecular Sciences 13th Annual Conference & Exhibition in Montreal, Canada.

19 Apr 2007

Novel method to expand the number of immune system "natural killer" cells from blood cells outside the body

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have devised a novel method to expand the number of immune system "natural killer (NK)" cells from blood cells outside the body.

19 Apr 2007

Method of mass-producing disease-fighting antibodies entirely within bacteria

The group led by Dr. George Georgiou developed the new antibody-production approach to improve upon processes used previously to identify new drugs.

19 Apr 2007

Vaccines to prevent or slow the growth of cancerous tumors

Mayo Clinic researchers have designed a new strategy in the promising field of cancer vaccine research that's proven to be successful in boosting T cells - the immune builders akin to a super defense force against cancer cells.

19 Apr 2007

Vaccine halts progression of pancreatic cancer in some patients

A dendritic cell-based therapeutic vaccine for pancreatic cancer developed by researchers at the University of Pittsburgh School of Medicine has successfully stalled the disease from progressing in a handful of patients three years post-vaccination.

18 Apr 2007

Immunomedics presents results on novel immunotoxin for prostate and lung cancers

Immunomedics has presented at the 2007 Annual Meeting of the American Association for Cancer Research results on the in vitro and in vivo evaluation of a novel immunotoxin, Rap-hRS7, for the potential treatment of prostate and lung cancers.

18 Apr 2007

FDA approves new bird flu vaccine from sanofi pasteur

The U.S. Food and Drug Administration (FDA) has announced the first approval in the United States of a vaccine for humans against the H5N1 influenza virus, commonly known as avian or bird flu.

18 Apr 2007

Scientists tackle cancer with different approaches

Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.

18 Apr 2007

Anadys Pharmaceuticals presents data showing ANA773 promotes anti-tumor activity of killer cells

Anadys Pharmaceuticals presented data from an in vitro study showing that the active metabolite of ANA773 promotes natural killer (NK) cell-mediated anti-tumor response by inducing cytokine secretion, cytolysis of tumor cells and enhanced antibody-dependent cellular cytotoxicity (ADCC), during a poster presentation at the Annual Meeting of the American Association of Cancer Research (AACR) in Los Angeles.

18 Apr 2007

High levels of antibodies - low levels of cancer!

Active immunisation can stimulate the body to produce highly efficient IgE antibodies that attack tumours.

17 Apr 2007

Peregrine's selective anti-VEGF antibodies shown to be as effective as Avastin

Peregrine Pharmaceuticals has reported that preclinical data presented at the Centennial Annual Meeting of the American Association for Cancer Research (AACR) showed that its monoclonal antibody 2C3, which selectively blocks vascular endothelial growth factor (VEGF) from binding to the second of the two VEGF receptors, demonstrates potent anti-cancer efficacy in a preclinical orthotopic model of pancreatic cancer.

17 Apr 2007

Investigational cancer 17-AAG drug targets critical proteins

A drug under study to treat various cancers selectively kills cancer cells because of its affinity for a modified version of a critical heat shock protein they contain, researchers have found.

16 Apr 2007

Abbott opens biotech facility in Puerto Rico

"This new facility is a key milestone for Abbott as we move to focus our resources and future growth on biologic and potent-drug manufacturing," said Lawrence Kraus, vice president of manufacturing, global pharmaceutical operations, Abbott.

11 Apr 2007

Combination Lyme disease vaccine proteins patented

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University have received U.S. Patent Number 7,179,448 for developing chimeric, or "combination," proteins that may advance the development of vaccines and diagnostic tests for Lyme disease.

9 Apr 2007