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Scientists discover new genetic variants linked to bowel cancer

Cancer Research UK-funded scientists have discovered four new genetic variants linked to bowel cancer by combining data from three major genome studies, reveals a study published in Nature Genetics.

16 Nov 2010

Spontaneous mutations can cause mental retardation

Dutch geneticists affiliated with the Radboud University Nijmegen Medical Centre present as a novel research paradigm that spontaneous mutations are an important cause of mental retardation.

15 Nov 2010

Scientists uncover DNA sequence variations associated with cardiac electrical activity

Scientists studying genetic data from nearly 50,000 people have uncovered several DNA sequence variations associated with the electrical impulses that make the heart beat. The findings, reported in Nature Genetics, may pave the way for a greater understanding of the mechanisms for abnormal heart rhythms and sudden cardiac death.

15 Nov 2010

Research on fruit flies reveal novel human pain gene

While it has become clear in recent years that susceptibility to pain has a strong inherited component, very little is known about actual "pain genes" and how they work. In the November 12th issue of Cell, researchers at Children's Hospital Boston and their collaborators report on a novel human pain gene. People with minor variations in this gene showed clear differences in susceptibility to acute heat pain and chronic back pain.

12 Nov 2010

German Genetic Diagnostics Act in need of amendment

Many aspects of the German Genetic Diagnostics Act (Gendiagnostikgesetz) are out of touch with the latest technology, almost impossible to implement in clinical practice, or even detrimental to the success of recognised screening tests, such as newborn screening. The Act, which came into force in February 2010, is in desperate need of amendment.

11 Nov 2010

New discovery can develop diagnostic test to identify gene mutation in AML

Decoding the DNA of a woman who died of acute myeloid leukemia (AML) has led researchers at Washington University School of Medicine in St. Louis to a gene that they found to be commonly altered in many patients who died quickly of the disease.

11 Nov 2010

Cognitive differences exist between modern humans, Neanderthals: Researchers

Whether cognitive differences exist between modern humans and Neanderthals is the subject of contentious disputes in anthropology and archaeology. Because the brain size range of modern humans and Neanderthals overlap, many researchers previously assumed that the cognitive capabilities of these two species were similar.

10 Nov 2010

NEWMEDS launches largest database to advance drug development for depressio, schizophrenia

In a remarkable and unprecedented collaboration NEWMEDS (Novel Methods leading to NeW MEdications in Depression and Schizophrenia) have pooled resources to bring together data of 23,401 anonymized patients from 67 trials on 11 compounds in over 25 countries to form the single largest database of clinical trial data ever amassed in psychiatric research.

10 Nov 2010

UC Davis researchers identify new pathway to repair oxidative-damaged DNA

UC Davis researchers have found a new pathway for repairing DNA damaged by oxygen radicals. The results are published this week in the journal Proceedings of the National Academy of Sciences.

10 Nov 2010

Genetic region linked to survival in patients with advanced bowel cancer

Scientists have discovered a genetic region linked to survival in patients with advanced bowel cancer, according to a study being presented at the National Cancer Research Institute (NCRI) Cancer Conference today (Tuesday).

9 Nov 2010

UC researchers receive four-year grant to study mechanism of malarial parasite replication in RBCs

Today, about half the world's population lives in areas at risk of malaria transmission. The disease is transmitted to humans through bites from mosquitoes, and each year causes hundreds of thousands of deaths worldwide, with about 1,500 of these in the United States.

8 Nov 2010

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Tiny variants in a protein that alerts the body to infection could explain how one in 300 HIV-infected people are able to resist the onset of AIDS for years without needing any treatment, researchers said Thursday in a study published online in the journal Science, Agence France-Presse reports

8 Nov 2010

Inviragen to present data on CHIKV vaccine at ASTMH meeting

Inviragen, a biotechnology company developing vaccines to protect against infectious diseases worldwide, together with investigators at the University of Texas Medical Branch (UTMB) and the Division of Vector Borne Diseases (DVBD) of the Centers for Disease Control and Prevention, will make an oral presentation today at the annual American Society of Tropical Medicine and Hygiene (ASTMH) meeting on preclinical results of the Company's experimental chikungunya virus (CHIKV) vaccine.

8 Nov 2010

New benchtop robotic workstation simplifies next-generation sequencing workflows

IntegenX, Inc. today at the 60th Annual American Society of Human Genetics Meeting announced the launch of their Apollo 324 System, a benchtop robotic workstation that automates the construction of DNA fragment libraries for next-generation sequencing.

8 Nov 2010

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

Agilent Technologies Inc. today announced a solution for exon analysis based on SurePrint G3 Exon Microarrays. The solution provides a major expansion of Agilent's portfolio of gene expression reagents, microarrays and bioinformatics systems. This new system, available in mid-November, enables researchers to examine alternately expressed exons according to recently updated content, providing a global picture of RNA expression.

4 Nov 2010

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics (ASHG) 60th Annual Meeting, on November 2-6, 2010, in Washington, D.C.

4 Nov 2010

Gene fusion prostate cancers susceptible to secondary mutations

Scientists at Weill Cornell Medical College have taken an important step toward a better understanding of prostate cancer by uncovering evidence that it is not one disease, as previously believed, but rather several factors which can be measured and, in the future, destroyed by targeted therapy.

4 Nov 2010

Affymetrix to contribute genotyping data to 1000 Genomes Project

Affymetrix, Inc. today announced that it will contribute genotyping data for a large set of validated rare and common genomic variants to the 1000 Genomes Project. This powerful data consists of genotyping information from more than 2 million single nucleotide polymorphisms (SNPs), and insertions/deletions (indels), many of which were not previously available from any source.

4 Nov 2010

New Ovation systems improve nucleic acid extraction from FFPE tissue samples

NuGEN Technologies, the provider of innovative RNA and DNA sample preparation solutions for genomic analysis, today announced the availability of the Ovation WGA FFPE System and the Ovation RNA-Seq FFPE System. These are the first commercially available products designed specifically to enable researchers to utilize next-generation sequencing (NGS) technologies to analyze nucleic acids extracted from Formalin-Fixed Paraffin-Embedded (FFPE) tissues.

3 Nov 2010

Study suggests heredity may play a role in determining infant's susceptibility to AOP

A potentially life-threatening challenge characterized by pauses in breathing that can last for more than 20 seconds, apnea of prematurity (AOP) affects more than 50 percent of premature infants and is almost universal in the smallest of preemies. Caused in part by an underdeveloped central nervous system that can't adequately regulate breathing outside of the womb, especially during sleep, AOP is not yet fully understood by scientists and remains a grave concern among neonatologists and parents alike.

3 Nov 2010

Genome News and Research

Scientists discover new genetic variants linked to bowel cancer

Spontaneous mutations can cause mental retardation

Scientists uncover DNA sequence variations associated with cardiac electrical activity

Research on fruit flies reveal novel human pain gene

German Genetic Diagnostics Act in need of amendment

New discovery can develop diagnostic test to identify gene mutation in AML

Cognitive differences exist between modern humans, Neanderthals: Researchers

NEWMEDS launches largest database to advance drug development for depressio, schizophrenia

UC Davis researchers identify new pathway to repair oxidative-damaged DNA

Genetic region linked to survival in patients with advanced bowel cancer

UC researchers receive four-year grant to study mechanism of malarial parasite replication in RBCs

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Inviragen to present data on CHIKV vaccine at ASTMH meeting

New benchtop robotic workstation simplifies next-generation sequencing workflows

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Gene fusion prostate cancers susceptible to secondary mutations

Affymetrix to contribute genotyping data to 1000 Genomes Project

New Ovation systems improve nucleic acid extraction from FFPE tissue samples

Study suggests heredity may play a role in determining infant's susceptibility to AOP

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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