Efficacy News and Research

RSS

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

National Institute of Standards and Technology researchers at the Institute for Bioscience and Biotechnology Research have demonstrated the most precise method yet to measure the structural configuration of monoclonal antibodies (mAbs), an important factor in determining the safety and efficacy of these biomolecules as medicines.

16 Apr 2015

UH Seidman Cancer Center uses SpaceOAR System to perform first-ever prostate cancer treatment

The radiation oncology team at UH Seidman Cancer Center at UH Geauga Medical Center performed the first-ever prostate cancer treatment on April 3 using a newly approved device. The device, called SpaceOAR System, enhances the efficacy of radiation treatment by protecting organs surrounding the prostate. The device, a temporary injectable gel, received FDA clearance on April 1.

16 Apr 2015

SELLAS inks exclusive global collaboration, license agreement with TrojanTec

SELLAS Life Sciences Group, a Swiss based, development-stage biopharmaceutical company with its main focus in developing innovative products for the treatment of various indications in Oncology and the Central Nervous System, today announced that it has signed an exclusive global collaboration and license agreement with TrojanTec Ltd, a UK-based Discovery Research and Development Company affiliated with Imperial College London, UK, for the development, marketing and commercialization of the innovative and proprietary TR-1 cancer therapeutic technology and drug.

15 Apr 2015

WHO issues public statement calling for transparency in medical research

WHO today issued a public statement calling for the disclosure of results from clinical trials for medical products, whatever the result.The move aims to ensure that decisions related to the safety and efficacy of vaccines, drugs and medical devices for use by populations are supported by the best available evidence.

15 Apr 2015

Cantab Connect CTIS-Abuse Liability product exceeds $1.5m sales in first 9 months

Cambridge Cognition Holdings plc,the developer of cognitive assessment software, announces that sales of Cantab Connect CTIS-Abuse Liability have exceeded £1m in its first 9 months from launch.

15 Apr 2015

Cardio3 BioSciences announces first patient enrollment in NKG2D CAR T-Cell Phase I clinical trial

Cardio3 BioSciences (C3BS), a leader in engineered cell-therapy treatments with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced the enrollment of the first patient in a Phase I clinical trial evaluating the Company’s lead CAR T-Cell therapy, NKG2D CAR T-Cell, in blood cancer patients with acute myeloid leukemia (AML) or multiple myeloma (MM).

15 Apr 2015

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

The Centers for Disease Control and Prevention (CDC), in partnership with the Sierra Leone College of Medicine and Allied Health Sciences and the Sierra Leone Ministry of Health and Sanitation, is now enrolling and vaccinating volunteers for the Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE).

15 Apr 2015

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

Genzyme, a Sanofi company, announced today that new longer-term data on its relapsing multiple sclerosis treatments, Aubagio (teriflunomide) and Lemtrada (alemtuzumab), will be featured during the 67th annual meeting of the American Academy of Neurology being held in Washington, D.C. April 18-25.

15 Apr 2015

Researchers call for earlier PAH diagnosis and treatment

A study has found that treatment of pulmonary arterial hypertension in patients younger than 55 years significantly improves their performance on the 6-minute walk test.

14 Apr 2015

NEFIGAN Trial of Nefecon for treatment of primary IgA nephropathy meets primary endpoint

Pharmalink AB, a specialty pharma company, today announces that the NEFIGAN Trial of Nefecon for the treatment of primary IgA nephropathy has fully met its primary efficacy endpoint at a planned interim analysis and been stopped early with respect to statistical analysis of the endpoint.

14 Apr 2015

Aeterna Zentaris plans to conduct Macrilen Phase 3 clinical study for AGHD

Aeterna Zentaris Inc. today announced plans to conduct a new, confirmatory Phase 3 clinical study to demonstrate the efficacy of Macrilen (macimorelin), a novel orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency ("AGHD"), as well as a dedicated thorough QT study to evaluate the effect of Macrilen on myocardial repolarization.

13 Apr 2015

ACA calls for 'conservative care first' approach to low-back pain

The American Chiropractic Association, in response to recent research calling into question the efficacy of acetaminophen in the management of spinal pain, strongly encourages patients and healthcare providers to consider the benefits of a conservative approach to back pain.

13 Apr 2015

VolitionRx adds three new laboratory automation systems to expedite sample analysis for its large ongoing clinical trials

Using its first installed robot, VolitionRx has recently completed the analysis of a first NuQ® assay on the complete set of 4,800 blood samples for its large retrospective, symptomatic population colorectal cancer study in collaboration with Hvidovre Hospital, University of Copenhagen, Denmark.

10 Apr 2015

Fewer patients take effective gout drug after steep price increase

Study finds that fewer patients with gout received useful colchicine drug after FDA actions led to 50x increase in price.

10 Apr 2015

Gratitude in heart attack patients improves cardiac health

Recognizing and giving thanks for the positive aspects of life can result in improved mental, and ultimately physical, health in patients with asymptomatic heart failure, according to research published by the American Psychological Association.

10 Apr 2015

Computer model provides policy prescription to optimize early HIV treatment

When a whole country's public health is at stake, making the wrong policy choices can cost lives and money. That's why researchers have worked to develop computer simulations of epidemics that can model individual behaviors and interactions to predict the spread of disease and the efficacy of interventions.

10 Apr 2015

Geneia, LVBCH partner to provide advanced health care analytics, insights to Pennsylvania employers

Geneia and the Lehigh Valley Business Coalition on Healthcare today announced a multi-year partnership to provide Pennsylvania employers with the advanced health care analytics and insights needed to manage the quality and cost of employee healthcare.

9 Apr 2015

National study comparing minimally invasive lumbar decompression (mild) with epidural steroid injections (ESIs) reaches full enrollment

Lumbar spinal stenosis is primarily a degenerative, age-related narrowing of the lower spinal canal resulting in compression of the nerve roots. MILD treats this compression by removing small portions of lamina and hypertrophic ligamentum flavum in a minimally invasive, outpatient procedure through an opening about the size of a baby aspirin...

9 Apr 2015

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Pharmacyclics, Inc. today announced longer-term data from a Phase II investigator-initiated study showing Waldenstrom's macroglobulinemia (WM) patients treated with IMBRUVICA (ibrutinib) experienced sustained disease control with an overall response rate (ORR) of 91% after a median of 19.1 months of treatment and a 2-year overall survival (OS) rate of 95%.

9 Apr 2015

Frontier Lifeline Hospital gets approval for cardiac stem cell research by the national Apex committee for stem cell research and clinical trial (heart regeneration)

Frontier Lifeline Hospital (FLL) has been already involved in cardiac stem cell therapy post the approval by Clinical Trial registry of India, Indian Council of Medical Research (ICMR) in 2010...

9 Apr 2015

Efficacy News and Research

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

UH Seidman Cancer Center uses SpaceOAR System to perform first-ever prostate cancer treatment

SELLAS inks exclusive global collaboration, license agreement with TrojanTec

WHO issues public statement calling for transparency in medical research

Cantab Connect CTIS-Abuse Liability product exceeds $1.5m sales in first 9 months

Cardio3 BioSciences announces first patient enrollment in NKG2D CAR T-Cell Phase I clinical trial

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

New longer-term data on Genzyme's relapsing MS treatments to be presented at AAN 2015

Researchers call for earlier PAH diagnosis and treatment

NEFIGAN Trial of Nefecon for treatment of primary IgA nephropathy meets primary endpoint

Aeterna Zentaris plans to conduct Macrilen Phase 3 clinical study for AGHD

ACA calls for 'conservative care first' approach to low-back pain

VolitionRx adds three new laboratory automation systems to expedite sample analysis for its large ongoing clinical trials

Fewer patients take effective gout drug after steep price increase

Gratitude in heart attack patients improves cardiac health

Computer model provides policy prescription to optimize early HIV treatment

Geneia, LVBCH partner to provide advanced health care analytics, insights to Pennsylvania employers

National study comparing minimally invasive lumbar decompression (mild) with epidural steroid injections (ESIs) reaches full enrollment

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Frontier Lifeline Hospital gets approval for cardiac stem cell research by the national Apex committee for stem cell research and clinical trial (heart regeneration)

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News