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Researchers discover FoxO1 protein interacts with macrophages to promote inflammatory response

Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly interacts with macrophages, promoting an inflammatory response that can lead to insulin resistance and diabetes. Contrarily, it also generates a negative feedback loop that can limit damage from excessive inflammation.

3 Nov 2010

Illumina, Expression Analysis support Cancer GWAS and Data Analysis Grant program

Expression Analysis today announced that it and Illumina, Inc. are jointly funding a Cancer GWAS (Genome-Wide Association Study) and Data Analysis Grant program to support cutting-edge projects that show promise in identifying genetic elements important to cancer research and treatment.

From Illumina, Inc. 3 Nov 2010

NanoString’s nCounter CNV CodeSets help detect genetic copy number variations

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the launch of a novel solution for detecting genetic copy number variations (CNVs) associated with disease susceptibility, drug response and cancer progression.

From NanoString Technologies 2 Nov 2010

Autism Consortium begins new therapeutic initiative on Translational Medicine

The Autism Consortium, an innovative Boston area collaboration of researchers, clinicians, funders and families dedicated to catalyzing research and enhancing clinical care for autism spectrum disorders (ASDs), announced that it will begin a new initiative on Translational Medicine and Autism Therapeutics. The new focus was introduced at the Consortium's fifth annual symposium held October 26th, 2010, at Harvard Medical School in Boston.

2 Nov 2010

ArcticDx develops test to determine inherited risk for AMD

Established in 2007 and based in Toronto, ArcticDx has developed a test, Macula Risk-, the first of its kind and specifically designed to determine one's inherited risk for age-related macular degeneration (AMD), the most common form of acquired blindness in the developed world, affecting over 10% of individuals. ArcticDx will use the PBDF investment to undertake studies in support of a planned filing for Food and Drug Administration (FDA) approval for Macula Risk.

2 Nov 2010

New algebraic model of DNA hybridization to measure cellular behavior

Researchers at New York University's Courant Institute of Mathematical Sciences have developed a novel algebraic model of DNA "hybridization," a process central to most biotechnology devices that monitor changes in cell's gene expression or characterize a cell's genome.

2 Nov 2010

Rubicon's PicoPlex kits provide DNA methylation profiling using next-generation sequencing

Rubicon Genomics today reported data demonstrating that its PicoPlex kits currently marketed for the analysis of single cells for research and diagnostic applications also provide important advantages for genetic and epigenetic profiling using next-generation sequencing (NGS).

2 Nov 2010

454 Life Sciences and DNA Electronics partner to develop high-throughput DNA sequencing system

454 Life Sciences, a Roche Company, announced today that it has entered an exclusive partnership with DNA Electronics for the development of a low-cost, high-throughput DNA sequencing system. As part of the agreement, Roche has signed a non-exclusive license for relevant IP from DNA Electronics' proprietary semiconductor technology portfolio, which enables sensitive detection of nucleotide incorporation during sequencing.

1 Nov 2010

Life Technologies announces launch of new sequencer to deliver genomic data

Life Technologies Corporation a provider of innovative life science solutions, today announced the launch of the 5500xl SOLiD Sequencer, a new instrument designed to deliver the industry's fastest and most accurate genomic data for cancer biology and genetic disease research.

1 Nov 2010

New NRNB center helps clinicians to study network biology

A new center called the National Resource for Network Biology (NRNB), based at the University of California, San Diego School of Medicine, will help clinicians analyze an ever-growing wealth of complex biological data and apply that knowledge to real problems and diseases.

30 Oct 2010

NIH director receives Mid-Atlantic Bio Lifetime Achievement Award

The 2010 Mid-Atlantic Bio Conference debuted yesterday with an opening reception during which National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, was honored with the Mid-Atlantic Bio Lifetime Achievement Award for his accomplishments in biomedical research and human services and his movement to increase translational work at NIH.

30 Oct 2010

North American children may be 'too clean'

Rising levels of allergic asthma and eczema in North American children have Canadian scientists wondering if there is such a thing as being "too clean." "We see auto-immune diseases like asthma and eczema increasing rapidly in North American children, but we don't see the same effect in children in the developing world," says Dr. B. Brett Finlay, a Professor in the Michael Smith Laboratories at the University of British Columbia.

29 Oct 2010

Life Technologies and BGI partner to offer whole human genome resequencing on SOLiD™ 4 System

Life Technologies Corporation and BGI (formerly Beijing Genomics Institute) announced today that they have partnered to offer whole human genome resequencing on the SOLiD™ 4 System. BGI, one of the world's largest genomic centers, has acquired 27 SOLiD 4 Systems, which will allow BGI to deliver 50 whole human genome sequences a month.

29 Oct 2010

EUCOMMTOOLS partners to receive 12 million euros research funding from European Commission

The findings will contribute to a better understanding of the pathogenesis of widespread diseases such as Alzheimer's, depression, diabetes, chronic lung diseases or cancer. Over the next five years, the eight EUCOMMTOOLS partners, coordinated by Professor Wolfgang Wurst of Helmholtz Zentrum M-nchen, will receive research funding amounting to approximately 12 million euros from the European Commission.

29 Oct 2010

University of Montreal contributes to '1000 Genomes Project'

Mutations in DNA are a normal part of life. Sometimes these variations give rise to unique and beneficial traits including the creation of a new species, other times they cause devastating diseases. We are now another step closer to capturing most of the DNA mutations in humans thanks to an international study cataloging all forms of DNA variation from five populations from Europe, East Asia, South Asia, West Africa and the Americas, in the "1000 Genomes Project".

29 Oct 2010

University of Maryland to establish major research enterprise for autoimmune diseases

With a new $45 million private gift from the family of a grateful patient, the University of Maryland School of Medicine is planning to establish the nation's only major research enterprise devoted to the study of autoimmune and inflammatory diseases such as celiac disease, multiple sclerosis, chronic obstructive pulmonary disease, asthma and Type 1 diabetes. The gift, from Indiana couple Ken and Shelia Cafferty, is the largest private donation in the history of the University System of Maryland.

29 Oct 2010

Study finds genetic variants that may modify breast cancer risk among women with BRCA2 mutation

An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer. The study was published today online in the open-access journal PLoS Genetics.

29 Oct 2010

International Congress at Spain highlights advances in neuroimmunological disease treatment

The complexity of the immune system and nervous system turn Neuroimmunology into one of the most exciting fields of modern biomedicine. Between October 26th and 30th takes place in Sitges (Barcelona, Spain) the X International Congress of Neuroimmunology of the International Society of Neuroimmunology.

29 Oct 2010

DiaGenic third quarter income increases from NOK -9.3 million to NOK -9.6 million

DiaGenic: The interim report for the third quarter 2010 was approved by the Board of Directors on 28 October 2010.

29 Oct 2010

Researchers depict new statistical algorithm to identify genetic variations for common diseases

A group of researchers at The Scripps Research Institute and the Scripps Translational Science Institute has published a paper that reviews new strategies for identifying collections of rare genetic variations that reveal whether people are predisposed to developing common conditions like diabetes and cancer.

29 Oct 2010

Genome News and Research

Researchers discover FoxO1 protein interacts with macrophages to promote inflammatory response

Illumina, Expression Analysis support Cancer GWAS and Data Analysis Grant program

NanoString’s nCounter CNV CodeSets help detect genetic copy number variations

Autism Consortium begins new therapeutic initiative on Translational Medicine

ArcticDx develops test to determine inherited risk for AMD

New algebraic model of DNA hybridization to measure cellular behavior

Rubicon's PicoPlex kits provide DNA methylation profiling using next-generation sequencing

454 Life Sciences and DNA Electronics partner to develop high-throughput DNA sequencing system

Life Technologies announces launch of new sequencer to deliver genomic data

New NRNB center helps clinicians to study network biology

NIH director receives Mid-Atlantic Bio Lifetime Achievement Award

North American children may be 'too clean'

Life Technologies and BGI partner to offer whole human genome resequencing on SOLiD™ 4 System

EUCOMMTOOLS partners to receive 12 million euros research funding from European Commission

University of Montreal contributes to '1000 Genomes Project'

University of Maryland to establish major research enterprise for autoimmune diseases

Study finds genetic variants that may modify breast cancer risk among women with BRCA2 mutation

International Congress at Spain highlights advances in neuroimmunological disease treatment

DiaGenic third quarter income increases from NOK -9.3 million to NOK -9.6 million

Researchers depict new statistical algorithm to identify genetic variations for common diseases

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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