Immune System News and Research

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Four types of gut bacteria can protect infants from asthma

New research by scientists at UBC and BC Children's Hospital finds that infants can be protected from getting asthma if they acquire four types of gut bacteria by three months of age.

1 Oct 2015

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

An experimental, biologic treatment, brodalumab, achieved 100 percent reduction in psoriasis symptoms in twice as many patients as a second, commonly used treatment, according to the results of a multicenter clinical trial led by Mount Sinai researchers and published online today in the New England Journal of Medicine.

1 Oct 2015

BiondVax to begin Phase IIb clinical trial of universal influenza vaccine in Europe

BiondVax Pharmaceuticals Ltd. announced today that it received regulatory clearance from the Hungarian Regulatory Authority (National Institute of Pharmacology and Nutrition, OGYEI) and the Central Ethics Committee in Budapest to initiate a Phase IIb clinical trial. The initiation meeting was scheduled for today, September 30, 2015, together with the partners from the UNISEC European Consortium.

30 Sep 2015

Novel portable device counts white blood cells in real time

A novel way to count white blood cells without a blood test, simply by applying a small device on the fingertip, is being developed by a team of young bioengineers. The technology, that combines an optical sensor with algorithms, has already three prototypes on the go and is specially designed to be used on chemotherapy patients, who could know their immune system levels in real time. It could also serve to detect serious infections.

30 Sep 2015

Leading cancer researchers address eight 'big questions'

Leading cancer researchers address eight of the "big questions" facing the field as part of the inaugural issue of Trends in Cancer, published by Cell Press.

30 Sep 2015

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

David Griggs, Ph.D., director of biology at Saint Louis University's Center for World Health & Medicine, has received a $1 million R01 grant from the National Institutes of Health to investigate the development of what could be a new class of drugs to treat bone diseases.

30 Sep 2015

New test identifies viruses that infect people and animals

A new test detects virtually any virus that infects people and animals, according to research at Washington University School of Medicine in St. Louis, where the technology was developed.

30 Sep 2015

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

A gene therapy approach to treating the progressive muscle wasting disorder Duchenne muscular dystrophy (DMD) that does not replace the mutated DMD gene but instead delivers the gene for ITGA7, a protein in skeletal muscle, led to reduced symptoms and significantly extended life span in a mouse model of severe DMD. Over-expression of ITGA7 did not elicit an immune reaction, further supporting its potential as a novel treatment for DMD, according to a new study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Sep 2015

Clinical trial shows nivolumab drug improves overall survival, quality of life in lung cancer patients

An international team of cancer researchers that included UT Southwestern Medical Center physicians announced "game-changing results" using the immunotherapy drug nivolumab to treat certain lung cancers that failed to respond to first-line therapies.

29 Sep 2015

Disruption of blood-CSF barrier may negatively affect progression of Alzheimer's disease

More and more data from preclinical and clinical studies strengthen the hypothesis that immune system-mediated actions contribute to and drive pathogenesis in Alzheimer's disease. The team of Roosmarijn Vandenbroucke in the Claude Libert Group (VIB/UGent) combined their knowledge and expertise related to inflammation with the expertise in Alzheimer's disease present in the Bart De Strooper Group (VIB/KU Leuven).

29 Sep 2015

Type-2 diabetes medication can affect the brain's reward system, reduce intake of food

Many studies have focused on how much we eat when we are hungry, but sometimes we eat just to feel better. A new dissertation at Sahlgrenska Academy shows that medication used for type-2 diabetes wich mimics the gut-brain hormone glucagon-like peptide-1, can affect the brain's reward system and reduce the intake of food.

29 Sep 2015

Duke Medicine scientists use transparent fish to show how Cryptococcal meningitis takes over the brain

Scientists at Duke Medicine are using transparent fish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,000 people worldwide each year.

29 Sep 2015

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Pregnant women with systemic lupus erythematosus (SLE), are at higher risk for adverse pregnancy outcomes, including preeclampsia, placental insufficiency, fetal death, miscarriages, and other complications.

29 Sep 2015

Phase II IMvigor 210 data shows atezolizumab may prevent progression of metastatic urothelial bladder cancer

Data presented today at the 2015 European Cancer Congress (ECC) demonstrates that the investigational immunotherapy atezolizumab may prevent progression of metastatic urothelial bladder cancer (mUBC) in all age groups by 2.1 months.

29 Sep 2015

Unique molecule can bind HIV-infected cells to killer T cells

A unique molecule developed at Duke Medicine, the University of North Carolina at Chapel Hill and MacroGenics, Inc., is able to bind HIV-infected cells to the immune system's killer T cells. It could become a key part of a shock-and-kill strategy being developed in the hope of one day clearing HIV infection.

29 Sep 2015

New drug works better than current treatments for advanced kidney cancer

A new drug has been found superior to current treatments in slowing the growth of advanced kidney cancer in patients who became resistant to the first-line therapies that had kept it in check, according to results from a clinical trial led by Dana-Farber Cancer Institute.

29 Sep 2015

New study broadens understanding of how the immune system responds to flu virus

A new study of influenza infection in an animal model broadens understanding of how the immune system responds to flu virus, showing that the process is more dynamic than usually described, engaging a broader array of biological pathways. The researchers say their findings may offer key insights for designing more effective vaccines in general.

29 Sep 2015

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

The National Institutes of Health has announced $46 million in research awards for the Human Placenta Project, an initiative to revolutionize understanding of the placenta. The awards will fund technology development and testing to assess placental function throughout pregnancy, with the ultimate goal of improving pregnancy outcomes and lifelong health.

29 Sep 2015

Occupational exposure to metalworking fluid associated with irreversible lung disease

Occupational exposure to fluid commonly used in metal machining operations may be related to a rare, irreversible lung disease, according to research presented at the European Respiratory Society's (ERS) International Congress today (28 September, 2015).

28 Sep 2015

Frequent infections in early life may increase risk factor for coeliac disease development in later life

Children with frequent infections in the first 18 months of life have a slightly increased risk of later developing coeliac disease compared with children who have few infections. This is the conclusion from a study by the Norwegian Institute of Public Health.

28 Sep 2015

Immune System News and Research

Four types of gut bacteria can protect infants from asthma

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

BiondVax to begin Phase IIb clinical trial of universal influenza vaccine in Europe

Novel portable device counts white blood cells in real time

Leading cancer researchers address eight 'big questions'

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

New test identifies viruses that infect people and animals

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

Clinical trial shows nivolumab drug improves overall survival, quality of life in lung cancer patients

Disruption of blood-CSF barrier may negatively affect progression of Alzheimer's disease

Type-2 diabetes medication can affect the brain's reward system, reduce intake of food

Duke Medicine scientists use transparent fish to show how Cryptococcal meningitis takes over the brain

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Phase II IMvigor 210 data shows atezolizumab may prevent progression of metastatic urothelial bladder cancer

Unique molecule can bind HIV-infected cells to killer T cells

New drug works better than current treatments for advanced kidney cancer

New study broadens understanding of how the immune system responds to flu virus

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

Occupational exposure to metalworking fluid associated with irreversible lung disease

Frequent infections in early life may increase risk factor for coeliac disease development in later life

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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