Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Neuroimaging for stroke patients may be unnecessarily costly and redundant

Neuroimaging for stroke patients may be unnecessarily costly and redundant, contributing to rising costs nationwide for stroke care, according to University of Michigan research.

6 Mar 2012

Scientists to investigate biochemical switch: P2X1 receptor

Scientists investigating a 'biochemical switch' linked to strokes and heart disease claim to have made an advance in understanding how it is 'turned on'.

6 Mar 2012

Scientists identify gene that causes adult-onset primary cervical dystonia

Researchers have identified a gene that causes adult-onset primary cervical dystonia, an often-painful condition in which patients' necks twist involuntarily.

5 Mar 2012

Merck fails to get FDA nod for new cholesterol lowering combo pill

The length of delay in approval is not clear yet as the FDA has called for additional study data on the compound. It combines generic Lipitor (Atorvastatin), the top-selling drug of all time, with Merck's cholesterol medicine Zetia (Ezetimibe).

5 Mar 2012

The Contraception Mandate is the end of individual liberty

In March 2010, the Democrat-controlled Congress forced the passage of the Patient Protection and Affordable Care Act (now known as ObamaCare) over the strong objections of the majority of Americans, most of whom were either already receiving taxpayer-funded health insurance or were satisfied with their private coverage.

5 Mar 2012

High blood pressure due to stress maybe due to the immune system

If stress is giving you high blood pressure, blame the immune system. T cells, helpful for fighting infections, are also necessary for mice to show an increase in blood pressure after a period of psychological stress, scientists have found.

5 Mar 2012

Inhalation of nitric oxide could help improve blood flow to ischemic brain

LMU researchers developed a new strategy for the treatment of stroke, which could help to improve blood flow to ischemic brain. Strokes are due to a localized reduction in the blood supply to the brain, mainly due to the blockage of a vessel by a blood clot.

5 Mar 2012

Thrombotech receives FDA IND approval for THR-18 Phase IIa clinical trial in stroke victims

Hadasit Bio-Holdings a publicly traded portfolio of biotech companies, all based on intellectual property developed and owned by Hadassah University Hospital, Israel's foremost medical research center, today announced Thrombotech Ltd., a portfolio company which Hadasit holds a 24% stake in, received an IND approval from the Food and Drug Administration enabling the initiation of a Phase IIa clinical trial in the U.S.

5 Mar 2012

Concert commences dosing in CTP-499 Phase 2 clinical trial for diabetic nephropathy

Concert Pharmaceuticals, Inc. today announced the initiation of dosing in a Phase 2 clinical trial evaluating CTP-499, an investigational drug for the treatment of diabetic nephropathy, the leading cause of chronic kidney disease (CKD) in the US.

5 Mar 2012

Concert, Fast Forward partner to advance new approach to treat spasticity and pain in MS

Concert Pharmaceuticals, Inc. and Fast Forward, LLC, the National Multiple Sclerosis Society's subsidiary devoted to bridging the gap between research and drug development, today announced a new collaboration to fund the preclinical advancement of C-21191, a deuterium-modified subtype-selective GABAA modulator developed by Concert with the therapeutic potential of treating spasticity and pain in multiple sclerosis (MS).

5 Mar 2012

FDA clears Covidien Solitaire FR revascularization device

Covidien, a leading global provider of healthcare products, today announced that the Solitaire FR revascularization device has been cleared by the U.S. Food and Drug Administration. The Solitaire FR device is intended to restore blood flow to the brain in patients suffering acute ischemic stroke by mechanically removing blood clots from blocked vessels.

5 Mar 2012

diaDexus introduces new PLAC Activity test in Europe

diaDexus, Inc., a company focused on the development and commercialization of proprietary cardiovascular diagnostic products, today announced the commercial launch of its CE-marked PLAC Test for Lp-PLA(2) Activity in Europe.

5 Mar 2012

New tool to map extent of traumatic brain injury

Traumatic brain injury among soldiers, sportsmen and women and accident survivors are common but may go undetected at the time of the event and manifest later in life. Now scientists are testing a tool that lights up the breaks these injuries leave deep in the brain's wiring, much like X-rays show broken bones.

4 Mar 2012

Early surgical intervention stops seizures and improves quality of life

While the thought of any type of surgery can be disconcerting, the thought of brain surgery can be downright frightening. But for people with a particular form of epilepsy, surgical intervention can literally be life-restoring.

3 Mar 2012

Union County Commission honors KF scientist with Women of Excellence Award

Helen Genova, PhD, research scientist at Kessler Foundation, received a Women of Excellence Award in Health Sciences from the Union County Commission on the Status of Women. In the Foundation's Neuropsychology and Neuroscience Laboratory, she investigates the effects of multiple sclerosis (MS) and traumatic brain injury on cognitive function with grant funding.

3 Mar 2012

Polymer-based medical implants can produce harmful free radicals

A polymer is a mesh of chains, which slowly break over time due to the pressure from ordinary wear and tear. When a polymer is squeezed, the pressure breaks chemical bonds and produces free radicals: ions with unpaired electrons, full of untapped energy. These molecules are responsible for aging, DNA damage and cancer in the human body.

3 Mar 2012

Trans fats raises stroke risk in women – aspirin lowers risk

A new study finds that older women who take in substantial amount of trans fats are more likely than their counterparts to suffer an ischemic stroke. However, the risk of stroke associated with trans fat intake was lower among women taking aspirin, according to the findings from University of North Carolina at Chapel Hill researchers. The report, “Trans Fat Intake, Aspirin and Ischemic Stroke Among Postmenopausal Women,” was published today online in the journal Annals of Neurology.

2 Mar 2012

FDA takes more time to decide on the fate of BMS & Pfizer’s joint venture anticlotting drug Eliquis

The U.S FDA have pushed back the deadline for deciding whether to approve an experimental anticlotting drug developed jointly by Pfizer Inc. and Bristol-Myers Squibb Co. The companies said late Wednesday that the Food and Drug Administration has set a new target date of June 28 for deciding whether to approve Eliquis. That’s three months later than originally scheduled.

2 Mar 2012

Pharmacological antagonist can inhibit body's response to cold

Researchers at St. Joseph's Hospital and Medical Center in Phoenix, Arizona, in collaboration with Amgen Inc. and several academic institutions, have discovered a way to block the body's response to cold using a drug. This finding could have significant implications in treating conditions such as stroke and cardiac arrest.

2 Mar 2012

First study to focus on platelet genetics in African Americans

Researchers, led by scientists from Johns Hopkins, have found five previously unknown gene mutations believed to be associated with elevated blood platelet counts in African-Americans, findings they say could someday lead to the development of new drugs to help prevent coronary artery disease.

2 Mar 2012