Antigen News and Research

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The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

Researchers evaluated the efficacy of low-dosage fluvoxamine (50 mg two times a day) over 10 days in the management of mild and moderate-SARS-CoV-2 infections in the US.

18 Jan 2023

The "Great Escape" by SARS-CoV-2 XBB.1

In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant of concern (VOC) Omicron, which emerged in late 2022.

17 Jan 2023

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

Researchers assess the risk of maternal, fetal, and neonatal morbidity and mortality in women diagnosed with COVID-19 during pregnancy.

17 Jan 2023

Future COVID-19 control will require vaccines that induce better mucosal immunity

In a recent study posted to the medRxiv* preprint server, researchers in France explored the relationship between long-term immunoglobulin (Ig)-A response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and taste and smell disorders.

17 Jan 2023

Researchers explore immune responses to mpox infections

In new research, researchers demonstrated that individuals recovering from mpox virus (MPXV) infection have neutralizing antibodies that target MPXV antigens A35R and H3L.

17 Jan 2023

What is the effectiveness of a multivalent exosome-based COVID-19 vaccine?

Researchers assessed the effectiveness of a multivalent exosome-based coronavirus disease 2019 (COVID-19) vaccine.

16 Jan 2023

What is the efficacy of the COVID-19 second booster versus the first booster with prior COVID-19 infections?

Researchers assessed the efficacy of the COVID-19 second booster vaccine compared to the first booster vaccine and the protection conferred by prior COVID-19 infection.

16 Jan 2023

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Researchers investigated how age-related T-cell defects impacted the effectiveness of mRNA-based COVID-19 vaccines.

16 Jan 2023

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

The leading cause of blindness in American adults is diabetic retinopathy, progressive damage to blood vessels in the light-sensitive tissue at the back of the eye.

14 Jan 2023

Recent findings on original antigenic sin and SARS-CoV-2

Researchers collated the findings of studies relating original antigenic sin with SARS-CoV-2 evolution.

13 Jan 2023

Discovery of a potential new target for new MPOX or broad pox vaccines

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and identification of antigens of MPXV IIa clade and IIb clade, in comparison to recipients of smallpox vaccines (ACAM2000 and IMVANEX).

12 Jan 2023

The impact of prior SARS-CoV-2 infection and vaccination on Omicron infection

researchers explored the effects of prior SARS-CoV-2 infection and vaccination on SARS-CoV-2 Omicron infection.

12 Jan 2023

Recent progress in the understanding of neuraminidase-specific antibodies for the development of universal influenza vaccines

A recent study published in Viruses reviewed the characteristics of neuraminidase with emphasis on the development of NA-based universal influenza vaccines.

12 Jan 2023

Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidly

A recent study posted to medRxiv* assessed the effectiveness of primary and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Netherlands.

11 Jan 2023

Researchers discover new structures on the surface of living B cells for the first time

Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly the function of their antigen receptors.

11 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Researchers investigated the efficacy of a booster dose of the bivalent mRNA COVID-19 vaccine in preventing severe outcomes during SARS-CoV-2 infections.

11 Jan 2023

Antigen News and Research

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

The "Great Escape" by SARS-CoV-2 XBB.1

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

Future COVID-19 control will require vaccines that induce better mucosal immunity

Researchers explore immune responses to mpox infections

What is the effectiveness of a multivalent exosome-based COVID-19 vaccine?

What is the efficacy of the COVID-19 second booster versus the first booster with prior COVID-19 infections?

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Study directly links gut leakage with retinopathy severity in people with Type 1 diabetes

Recent findings on original antigenic sin and SARS-CoV-2

Discovery of a potential new target for new MPOX or broad pox vaccines

The impact of prior SARS-CoV-2 infection and vaccination on Omicron infection

Recent progress in the understanding of neuraminidase-specific antibodies for the development of universal influenza vaccines

Study shows booster vaccinations against SARS-CoV-2 effective but protection wanes rapidly

Researchers discover new structures on the surface of living B cells for the first time

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

COVID-19 outcomes in Rituximab treated patients

Simple method increases the efficacy of T cell therapy by cytokine conjugation

2022: a year in MIS-C research

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

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